HK1247101A1 - 用於治療神經肌肉、神經變性、自身免疫、發育和/或代謝疾病的腦源性神經營養因子(bdnf)的誘導表達 - Google Patents

用於治療神經肌肉、神經變性、自身免疫、發育和/或代謝疾病的腦源性神經營養因子(bdnf)的誘導表達

Info

Publication number
HK1247101A1
HK1247101A1 HK18106712.4A HK18106712A HK1247101A1 HK 1247101 A1 HK1247101 A1 HK 1247101A1 HK 18106712 A HK18106712 A HK 18106712A HK 1247101 A1 HK1247101 A1 HK 1247101A1
Authority
HK
Hong Kong
Prior art keywords
bdnf
neuromuscular
developmental
neurodegenerative
autoimmune
Prior art date
Application number
HK18106712.4A
Other languages
English (en)
Inventor
Robert Alonso
John Gerard Geisler
Original Assignee
Mitochon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitochon Pharmaceuticals Inc filed Critical Mitochon Pharmaceuticals Inc
Publication of HK1247101A1 publication Critical patent/HK1247101A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • A61K31/06Phenols the aromatic ring being substituted by nitro groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
HK18106712.4A 2015-01-22 2018-05-24 用於治療神經肌肉、神經變性、自身免疫、發育和/或代謝疾病的腦源性神經營養因子(bdnf)的誘導表達 HK1247101A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562106365P 2015-01-22 2015-01-22
PCT/US2016/014312 WO2016118741A1 (en) 2015-01-22 2016-01-21 Induced expression of brain derived neurotrophic factor (bdnf) for treatment of neuromuscular, neurodegenerative, autoimmune, developmental and/or metabolic diseases

Publications (1)

Publication Number Publication Date
HK1247101A1 true HK1247101A1 (zh) 2018-09-21

Family

ID=55310938

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18106712.4A HK1247101A1 (zh) 2015-01-22 2018-05-24 用於治療神經肌肉、神經變性、自身免疫、發育和/或代謝疾病的腦源性神經營養因子(bdnf)的誘導表達

Country Status (13)

Country Link
US (6) US9763896B2 (zh)
EP (2) EP4306167A3 (zh)
JP (3) JP6951976B2 (zh)
KR (1) KR102690198B1 (zh)
CN (2) CN116617195A (zh)
AU (2) AU2016209255B2 (zh)
BR (1) BR112017015721A2 (zh)
CA (1) CA2974092A1 (zh)
ES (1) ES2961334T3 (zh)
HK (1) HK1247101A1 (zh)
MX (2) MX2017009402A (zh)
PT (1) PT3247340T (zh)
WO (1) WO2016118741A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102690198B1 (ko) * 2015-01-22 2024-07-30 미토콘 파마슈티칼스, 인크. 신경근육, 신경퇴행, 자가면역, 발달 및/또는 대사 질환의 치료를 위한 뇌 유도된 신경친화성 인자(bdnf)의 유도된 발현
SI3565806T1 (sl) 2017-01-06 2022-07-29 Rivus Pharmaceuticals, Inc. Novi fenilni derivati
JP2020506231A (ja) * 2017-01-31 2020-02-27 パオロ エル マンフレディ 神経系の障害並びにその症状及び徴候の処置又は予防のため並びに疾患及び細胞の老化並びにその症状及び徴候に対する細胞保護のための化合物
US10278960B2 (en) 2017-06-23 2019-05-07 Enzo Biochem, Inc. Sphingosine pathway modulating compounds for the treatment of cancers
US10660879B2 (en) 2017-06-23 2020-05-26 Enzo Biochem, Inc. Sphingosine pathway modulating compounds for the treatment of cancers
US20230363418A1 (en) * 2020-09-29 2023-11-16 Cefo Co., Ltd. Composition for preventing or treating neuropsychologic disease, comprising manf
WO2023205625A2 (en) * 2022-04-18 2023-10-26 Mitochon Pharmaceuticals, Inc. 2,4 dnp and prodrugs thereof for treatment of pulmonary and autoimmune diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6664297B1 (en) * 2000-10-18 2003-12-16 Universidade Federal Do Rio De Janeiro Methods for inhibition and dissolution of amyloidoses by administration of compositions comprising 2,4-dinitrophenol
US7135575B2 (en) * 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
US20100130597A1 (en) 2007-07-06 2010-05-27 The United State Of America, As Represented By The Secretary Of The Dept Of Health And Human Service Dna-pkcs modulates energy regulation and brain function
WO2015031756A1 (en) * 2013-08-30 2015-03-05 Yale University Novel 2,4-dinitrophenol formulations and methods using same
KR102690198B1 (ko) * 2015-01-22 2024-07-30 미토콘 파마슈티칼스, 인크. 신경근육, 신경퇴행, 자가면역, 발달 및/또는 대사 질환의 치료를 위한 뇌 유도된 신경친화성 인자(bdnf)의 유도된 발현

Also Published As

Publication number Publication date
AU2016209255A1 (en) 2017-08-10
JP2021080286A (ja) 2021-05-27
KR102690198B1 (ko) 2024-07-30
US11717497B2 (en) 2023-08-08
CN107405315A (zh) 2017-11-28
EP4306167A2 (en) 2024-01-17
MX2022005937A (es) 2022-06-29
US9974755B2 (en) 2018-05-22
WO2016118741A1 (en) 2016-07-28
JP7440092B2 (ja) 2024-02-28
EP4306167A3 (en) 2024-03-20
JP6951976B2 (ja) 2021-10-20
EP3247340A1 (en) 2017-11-29
ES2961334T3 (es) 2024-03-11
PT3247340T (pt) 2023-10-31
US10220006B2 (en) 2019-03-05
US10864173B2 (en) 2020-12-15
US20180125794A1 (en) 2018-05-10
US20190142765A1 (en) 2019-05-16
JP2022173519A (ja) 2022-11-18
US20170065536A1 (en) 2017-03-09
JP2018502898A (ja) 2018-02-01
EP3247340B1 (en) 2023-08-02
AU2021240120A1 (en) 2021-10-28
US20160213625A1 (en) 2016-07-28
US9763896B2 (en) 2017-09-19
AU2016209255B2 (en) 2021-07-01
US20210052513A1 (en) 2021-02-25
BR112017015721A2 (pt) 2018-04-10
US20240156750A1 (en) 2024-05-16
CN116617195A (zh) 2023-08-22
MX2017009402A (es) 2017-12-04
CA2974092A1 (en) 2016-07-28
KR20170104597A (ko) 2017-09-15

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