HK1246781A1 - 呼吸道合胞病毒抑制劑 - Google Patents

呼吸道合胞病毒抑制劑

Info

Publication number
HK1246781A1
HK1246781A1 HK18106131.7A HK18106131A HK1246781A1 HK 1246781 A1 HK1246781 A1 HK 1246781A1 HK 18106131 A HK18106131 A HK 18106131A HK 1246781 A1 HK1246781 A1 HK 1246781A1
Authority
HK
Hong Kong
Prior art keywords
respiratory syncytial
syncytial virus
virus inhibitors
inhibitors
respiratory
Prior art date
Application number
HK18106131.7A
Other languages
English (en)
Inventor
S‧艾若莎
K‧爾斯馬克
G‧卡拉亞諾夫
M‧雷約翰馬可
L‧薩爾瓦多奧登
H‧韋斯特利德
H‧瓦赫林格
M‧伯特蘭
C‧布洛楚
E‧吉羅
C‧庫恩
C‧斯圖里諾
J‧拜朗德
F‧斯奇古戈曼布林
Original Assignee
美迪維爾公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 美迪維爾公司 filed Critical 美迪維爾公司
Publication of HK1246781A1 publication Critical patent/HK1246781A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
HK18106131.7A 2015-07-30 2018-05-11 呼吸道合胞病毒抑制劑 HK1246781A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1551051 2015-07-30
SE1650843 2016-06-15
PCT/SE2016/050733 WO2017018924A1 (en) 2015-07-30 2016-07-28 Respiratory syncytial virus inhibitors

Publications (1)

Publication Number Publication Date
HK1246781A1 true HK1246781A1 (zh) 2018-09-14

Family

ID=57884956

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18106131.7A HK1246781A1 (zh) 2015-07-30 2018-05-11 呼吸道合胞病毒抑制劑

Country Status (10)

Country Link
US (1) US20190002436A1 (zh)
EP (1) EP3328859B1 (zh)
JP (1) JP6739516B2 (zh)
CN (1) CN107922407B (zh)
AU (1) AU2016298355A1 (zh)
BR (1) BR112018001726A2 (zh)
CA (1) CA2993144A1 (zh)
HK (1) HK1246781A1 (zh)
MX (1) MX2018001317A (zh)
WO (1) WO2017018924A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018038667A1 (en) * 2016-08-25 2018-03-01 Medivir Ab Respiratory syncytial virus inhibitors
WO2018038668A1 (en) * 2016-08-25 2018-03-01 Medivir Ab Respiratory syncytial virus inhibitors
CN108358832A (zh) * 2017-12-29 2018-08-03 上海艾康睿医药科技有限公司 一种合成4-[(2-氨基-4-氯)苯基]-氨基-n-哌啶甲酸乙酯的方法
CN114269747B (zh) * 2019-11-18 2023-04-18 苏州恩华生物医药科技有限公司 一种1’,2’-二氢-3’h-螺[环丁烷1,4’-异喹啉]-3’-酮衍生物及其应用
US11351149B2 (en) 2020-09-03 2022-06-07 Pfizer Inc. Nitrile-containing antiviral compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016535043A (ja) * 2013-10-29 2016-11-10 メディヴィル・アクチエボラーグ キナゾリンベースの呼吸器合胞体ウイルス阻害剤
WO2015065336A1 (en) * 2013-10-29 2015-05-07 Medivir Ab Respiratory syncytial virus inhibitors
CN104693211A (zh) * 2013-12-10 2015-06-10 南京明德新药研发股份有限公司 作为抗病毒剂的咪唑衍生物及其制药用途

Also Published As

Publication number Publication date
MX2018001317A (es) 2018-04-30
BR112018001726A2 (pt) 2018-09-18
EP3328859A1 (en) 2018-06-06
CN107922407B (zh) 2020-09-25
JP6739516B2 (ja) 2020-08-12
EP3328859B1 (en) 2020-06-03
US20190002436A1 (en) 2019-01-03
WO2017018924A1 (en) 2017-02-02
CN107922407A (zh) 2018-04-17
JP2018525372A (ja) 2018-09-06
EP3328859A4 (en) 2019-03-13
CA2993144A1 (en) 2017-02-02
AU2016298355A1 (en) 2018-02-08

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