HK1246171A1 - 用於治療或改善與內源性類視黃醇缺乏有關的視覺障礙的治療方案和方法 - Google Patents

用於治療或改善與內源性類視黃醇缺乏有關的視覺障礙的治療方案和方法

Info

Publication number
HK1246171A1
HK1246171A1 HK18105673.3A HK18105673A HK1246171A1 HK 1246171 A1 HK1246171 A1 HK 1246171A1 HK 18105673 A HK18105673 A HK 18105673A HK 1246171 A1 HK1246171 A1 HK 1246171A1
Authority
HK
Hong Kong
Prior art keywords
treating
disorders associated
therapeutic regimen
visual disorders
endogenous retinoid
Prior art date
Application number
HK18105673.3A
Other languages
English (en)
Inventor
H‧A‧斯特朗
S‧卡登
Original Assignee
Retinagenix Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Retinagenix Therapeutics Inc filed Critical Retinagenix Therapeutics Inc
Publication of HK1246171A1 publication Critical patent/HK1246171A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18105673.3A 2010-04-19 2013-06-25 用於治療或改善與內源性類視黃醇缺乏有關的視覺障礙的治療方案和方法 HK1246171A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32576310P 2010-04-19 2010-04-19
US40743610P 2010-10-27 2010-10-27
US201161447611P 2011-02-28 2011-02-28

Publications (1)

Publication Number Publication Date
HK1246171A1 true HK1246171A1 (zh) 2018-09-07

Family

ID=44788663

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105673.3A HK1246171A1 (zh) 2010-04-19 2013-06-25 用於治療或改善與內源性類視黃醇缺乏有關的視覺障礙的治療方案和方法

Country Status (18)

Country Link
US (3) US9173856B2 (zh)
EP (1) EP2563350B1 (zh)
JP (4) JP6250389B2 (zh)
KR (2) KR101851249B1 (zh)
CN (2) CN102939081A (zh)
AU (3) AU2011244024B2 (zh)
BR (1) BR112012026939A2 (zh)
CA (1) CA2796991A1 (zh)
CL (1) CL2012002942A1 (zh)
CO (1) CO6640227A2 (zh)
HK (1) HK1246171A1 (zh)
IL (1) IL222567A (zh)
MX (1) MX339834B (zh)
NO (1) NO20121362A1 (zh)
NZ (1) NZ603331A (zh)
RU (1) RU2622763C2 (zh)
SG (2) SG184971A1 (zh)
WO (1) WO2011132084A2 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011034551A2 (en) 2009-09-15 2011-03-24 Qlt Inc. Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle
KR101851249B1 (ko) 2010-04-19 2018-06-20 노벨리언 테라퓨틱스 인코포레이티드 내인성 레티노이드 결핍과 연관된 시각 장애의 치료 또는 완화를 위한 치료용 조성물, 제형 및 키트
NZ629267A (en) * 2012-03-01 2016-11-25 Quadra Logic Tech Inc Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency
WO2015023902A2 (en) * 2013-08-14 2015-02-19 Qlt Inc. Therapeutic regimens and methods for improving visual function in visual disorders associated with impaired dark adaptation and/or impaired low luminance vision
US11845951B2 (en) 2017-09-29 2023-12-19 Toolgen Incorporated Gene manipulation for treatment of retinal dysfunction disorder

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3196078A (en) 1962-01-30 1965-07-20 Ortho Pharma Corp Process for combating retinits pigmentosa
US3517067A (en) 1964-02-11 1970-06-23 Eastman Kodak Co Syntheses of quaternary phosphonium salts
DE2300107C2 (de) 1973-01-03 1982-03-11 Basf Ag, 6700 Ludwigshafen Vitamin A-Säureanilid-4-carbonsäureäthylester, Verfahren zu seiner Herstellung und diesen enthaltende Zubereitungen
CH590222A5 (zh) 1973-08-21 1977-07-29 Hoffmann La Roche
US4022913A (en) 1973-09-13 1977-05-10 Hoffmann-La Roche Inc. High potency vitamin A compositions
DE2456959A1 (de) 1974-12-03 1976-06-16 Basf Ag 4-(e)- und 4-(z)-7-methyl-9-(2,6,6trimethyl-1-cyclohexen-1-yl)-nona-2,4,6,8tetraencarbonsaeure, ihre derivate und diese enthaltende zubereitungen
US4532133A (en) 1983-05-24 1985-07-30 Basf Wyandotte Corporation Low temperature stable, emulsifiable vitamin A concentrates
CA1282326C (en) 1984-12-14 1991-04-02 Paul J. Jarosz Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient
JPS61275266A (ja) 1985-05-28 1986-12-05 Taisho Pharmaceut Co Ltd レチノイド誘導体
CZ282548B6 (cs) 1992-01-22 1997-08-13 F. Hoffmann-La Roche Ag Farmaceutický přípravek
US5310764A (en) 1992-05-08 1994-05-10 Steven Baranowitz Treatment of age related macular degeneration with beta-carotene
JPH06340525A (ja) 1993-06-02 1994-12-13 Lion Corp 安定な低眼刺激性ビタミンａ類可溶化点眼剤
EP0754046A1 (en) 1994-04-04 1997-01-22 FREEMAN, William R. Use of phosphonylmethoxyalkyl nucleosides for the treatment of raised intraocular pressure
US5425560A (en) 1994-04-21 1995-06-20 Strattec Security Corporation Squeeze latch
RU2106843C1 (ru) 1994-06-29 1998-03-20 Красноярская государственная медицинская академия Способ лечения близорукости
JPH08198746A (ja) 1995-01-18 1996-08-06 Lion Corp 可溶化点眼剤
US5837728A (en) 1995-01-27 1998-11-17 Molecular Design International 9-cis retinoic acid esters and amides and uses thereof
US5489611A (en) 1995-02-10 1996-02-06 Warner-Lambert Company Method for lowering plasma levels of lipoprotein (a)
US5620970A (en) 1995-06-05 1997-04-15 Alcon Laboratories, Inc. Topical ophthalmic carbonic anhydrase inhibitor formulations
AU6390096A (en) 1995-07-20 1997-02-18 Pharmacia & Upjohn Company Stable clear solutions of non-steroidal anti-inflammatory drugs for incorporation into gelatin capsules
US5716627A (en) 1996-04-25 1998-02-10 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester
EP0908179A1 (en) 1997-08-23 1999-04-14 Werner Bollag Treatment of cell-mediated immune diseases
ZA989513B (en) 1997-10-21 1999-04-21 Alcon Lab Inc Compositions containing histamine H2 agonists and methods of use in treating dry eye
US6391924B1 (en) 1997-12-10 2002-05-21 Hampar Karageozian Taurine derivatives useable in the treatment of ophthalmic disorders
US6552009B2 (en) 1998-07-16 2003-04-22 Gentrix Llc Compositions and methods of treating abnormal cell proliferation
US6267985B1 (en) 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
US6372463B1 (en) 1999-05-06 2002-04-16 The President & Fellows Of Harvard College Mutations in nucleic acid molecules encoding 11-CIS retinol dehydrogenase, the mutated proteins, and uses thereof
US6300328B1 (en) 1999-08-06 2001-10-09 Alcon Universal Ltd. Selective inhibitors of adenosine monophosphate deaminase for the treatment of optic nerve and retinal damage
US20020028849A1 (en) 2000-04-18 2002-03-07 Godkin James D. Use of retinol in assisted-reproduction protocols
US6696069B2 (en) 2000-06-30 2004-02-24 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Skin care cosmetic compositions containing phosphates and/or sulfates of branched alcohols and/or ethoxylates thereof
US20040077604A1 (en) 2001-12-19 2004-04-22 Lenard Lichtenberger Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity
JP4210115B2 (ja) 2001-01-11 2009-01-14 チェビジェン・インコーポレイテッド 新規レチノール誘導体および製造方法および用途
EP1381276A4 (en) 2001-04-13 2005-02-02 Univ Pennsylvania METHOD FOR TREATMENT OR DEVELOPMENT SLUDGE DEGRADATION
ITMI20012366A1 (it) 2001-11-09 2003-05-09 Farmatron Ltd Sistemi terapeutici stabilizzati a rilascio immediato e/o modificato per la somministrazione orale di principi attivi e/o eccipienti e/o ali
US7875728B2 (en) 2001-11-30 2011-01-25 Valocor Therapeutics, Inc. Hydrazonopyrazole derivatives and their use as therapeutics
EP1476147A4 (en) 2002-01-18 2005-03-09 Tatton Technologies Llc METHODS OF TREATING VIEW DISORDERS
US20030215413A1 (en) 2002-03-22 2003-11-20 L'oreal Compositions containing stabilized retinoid
US20040097587A1 (en) 2002-03-27 2004-05-20 Arbiser Jack L Compositions and methods of treatment of ulcerating diseases, burns, and related conditions
US20030228277A1 (en) 2002-03-29 2003-12-11 Gehlsen Kurt R. Use of ROM production and release inhibitors to treat and prevent intraocular damage
JP3854524B2 (ja) * 2002-04-01 2006-12-06 ピアス株式会社 油溶性成分安定化組成物及びその組成物を配合した化粧料、並びに油溶性成分の安定化方法
EP1527774A1 (en) 2003-11-03 2005-05-04 Basilea Pharmaceutica AG New formulation for retinoid-containing soft gelatin capsules
AU2004222279B2 (en) * 2003-03-14 2010-01-21 University Of Washington Retinoid replacements and opsin agonists and methods for the use thereof
EP1510133A1 (en) 2003-09-01 2005-03-02 Belovo S.A., Egg Science & Technology Balanced oil composition
EP2412304B1 (en) 2003-09-04 2016-08-03 The UAB Research Foundation Method and apparatus for the detection of impaired dark adaptation
US7706863B2 (en) 2004-01-21 2010-04-27 University Of Washington Methods for assessing a physiological state of a mammalian retina
KR20060135819A (ko) 2004-02-17 2006-12-29 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 황반변성을 포함하는 안과질환의 관리
AU2005221283C1 (en) 2004-03-17 2011-02-03 Lars Michael Larsen Prevention of retinopathy by inhibition of the visual cycle
US7951841B2 (en) 2004-06-18 2011-05-31 University Of Washington Retinal derivatives and methods for the use thereof for the treatment of visual disorders
EP1768657B1 (en) * 2004-06-23 2008-08-13 Sirion Therapeutics, Inc. Methods and compositions for treating ophthalmic conditions with retinyl derivates
US20060240098A1 (en) 2004-07-14 2006-10-26 Aphios Corporation Formulations for hyperforin-enriched hypericum fractions
AU2005287343A1 (en) 2004-08-18 2006-03-30 Sirion Therapeutics, Inc. Combination compositions comprising 13-cis-retinyl derivatives and uses thereof to treat opthalmic disorders
WO2006039551A2 (en) * 2004-09-30 2006-04-13 The Regents Of The University Of California Local administration of retinoids to treat deficiencies in dark adaptation
US20060177392A1 (en) 2005-02-10 2006-08-10 William Walden Oil-based composition for acne
JP2009514890A (ja) 2005-11-07 2009-04-09 マーティ・ファーマシューティカルズ・インク テトラヒドロカンナビノールの改良された送達
US8202541B2 (en) 2006-02-07 2012-06-19 U.S. Nutraceuticals, LLC Dietary supplement composition for blood lipid health
WO2008013983A2 (en) 2006-07-27 2008-01-31 University Of Florida Research Foundation, Inc. Opsin stabilizing compounds and methods of use
CN107652212B (zh) 2007-01-15 2019-11-15 于崇曦 维生素a酸类和类维生素a酸化合物的前药
US8877809B2 (en) 2007-09-12 2014-11-04 The Trustees Of Columbia University In The City Of New York Compositions and methods for treating macular degeneration
CA2714530C (en) * 2008-02-11 2018-09-25 University Of Washington Methods for the treatment and prevention of age-related retinal dysfunction
WO2011034551A2 (en) 2009-09-15 2011-03-24 Qlt Inc. Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle
KR101851249B1 (ko) 2010-04-19 2018-06-20 노벨리언 테라퓨틱스 인코포레이티드 내인성 레티노이드 결핍과 연관된 시각 장애의 치료 또는 완화를 위한 치료용 조성물, 제형 및 키트
NZ629267A (en) 2012-03-01 2016-11-25 Quadra Logic Tech Inc Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency

Also Published As

Publication number Publication date
IL222567A0 (en) 2012-12-31
KR20180043846A (ko) 2018-04-30
CA2796991A1 (en) 2011-10-27
NO20121362A1 (no) 2012-11-19
JP2019178162A (ja) 2019-10-17
KR101851249B1 (ko) 2018-06-20
BR112012026939A2 (pt) 2016-07-12
US20190029986A1 (en) 2019-01-31
SG184971A1 (en) 2012-11-29
RU2622763C2 (ru) 2017-06-19
JP2016014047A (ja) 2016-01-28
IL222567A (en) 2017-06-29
JP2017222721A (ja) 2017-12-21
CO6640227A2 (es) 2013-03-22
AU2011244024A1 (en) 2012-11-08
EP2563350A4 (en) 2013-09-18
WO2011132084A3 (en) 2012-02-16
RU2012148812A (ru) 2014-05-27
EP2563350A2 (en) 2013-03-06
KR20130054961A (ko) 2013-05-27
WO2011132084A2 (en) 2011-10-27
US9987245B2 (en) 2018-06-05
CN107308143A (zh) 2017-11-03
AU2017268684A1 (en) 2017-12-21
CL2012002942A1 (es) 2013-04-12
AU2016201432A1 (en) 2016-03-24
MX2012012199A (es) 2013-02-11
CN102939081A (zh) 2013-02-20
NZ603331A (en) 2015-02-27
SG10201507819VA (en) 2015-10-29
JP6250389B2 (ja) 2017-12-20
AU2011244024B2 (en) 2015-12-10
EP2563350B1 (en) 2020-10-14
JP2013527844A (ja) 2013-07-04
US20110257266A1 (en) 2011-10-20
US9173856B2 (en) 2015-11-03
MX339834B (es) 2016-06-14
US20170087114A1 (en) 2017-03-30

Similar Documents

Publication Publication Date Title
HK1225939A1 (zh) 用於測量和治療解剖結構的裝置和方法
HK1204271A1 (zh) 在接受抑制素治療的受試者中降低心血管事件風險的方法
HK1210978A1 (zh) 皮膚病學治療的方法和裝置
EP2736474A4 (en) DEVICE AND METHOD FOR NEUROMUSCULAR THERAPY
EP2670733A4 (en) HDAC HEMMER AND THERAPY PROCESS THEREFOR
GB2509271B (en) Patient-specific sacroiliac guides and associated methods
GB2492597B (en) Transformer with an inverter system and an inverter system comprising the transformer
EP2788075A4 (en) DEVICE AND METHOD FOR REDUCING THE TRANSTHORACOID IMPEDANCE OF A PATIENT
IL232734A0 (en) A method and device for verifying persistence in the treatment of a dental device
EP2827935A4 (en) DEVICES AND METHODS FOR ENDOVASCULAR ACCESS AND THERAPY
ZA201304334B (en) Methods for diagnosing and treating eye-length related disorders
EP2731509A4 (en) APPARATUS AND METHOD FOR REPOSITIONING A BODY PART
HK1205469A1 (zh) 用於在與內源性維甲酸類缺乏相關的視覺障礙中改善視覺功能的治療方案和方法
HK1214274A1 (zh) 用於治療肝臟疾病和心血管疾病的脂肽
EP2890317A4 (en) METHOD AND APPARATUS FOR DERMATOLOGICAL TREATMENT
EP2781104A4 (en) DISPLAY DEVICE AND CONTENT PROCESS FOR THIS
EP2745530A4 (en) DISPLAY DEVICE AND CONTENT PROVIDING METHOD USING THE SAME
EP2872216A4 (en) METHOD AND APPARATUS FOR DERMATOLOGICAL TREATMENT
EP2688585A4 (en) METHOD AND COMPOSITIONS FOR IMPROVING ANTIANGIOGEN THERAPY WITH ANTIINTEGRINES
HK1246171A1 (zh) 用於治療或改善與內源性類視黃醇缺乏有關的視覺障礙的治療方案和方法
HK1192118A1 (zh) 低卡路里發酵乳及其製造方法
EP2858554A4 (en) METHOD AND SYSTEM FOR IN VIVO HYDROGEN PEROXIDE DETECTION WITH ULTRASOUND
HK1176403A1 (zh) 聯合療法和用於評估對治療的抗性的方法
EP2640397A4 (en) METHODS OF TREATING FIBROMYALGIA AND CHRONIC FATIGUE SYNDROME
PT2630475T (pt) Método de diagnóstico e tratamento