HK1223957A1 - 獲取 結合肽的方法,產生該肽的過程,用所述方法/過程獲取的 結合肽以及該肽的用途 - Google Patents

獲取 結合肽的方法,產生該肽的過程,用所述方法/過程獲取的 結合肽以及該肽的用途

Info

Publication number
HK1223957A1
HK1223957A1 HK16112331.5A HK16112331A HK1223957A1 HK 1223957 A1 HK1223957 A1 HK 1223957A1 HK 16112331 A HK16112331 A HK 16112331A HK 1223957 A1 HK1223957 A1 HK 1223957A1
Authority
HK
Hong Kong
Prior art keywords
april
binding peptides
peptides
producing
obtaining
Prior art date
Application number
HK16112331.5A
Other languages
English (en)
Inventor
Eenennaam Hans Van
Elsas Andrea Van
Lilian Driessen
Jan Paul Medema
Original Assignee
Aduro Biotech Holdings Europe B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aduro Biotech Holdings Europe B V filed Critical Aduro Biotech Holdings Europe B V
Publication of HK1223957A1 publication Critical patent/HK1223957A1/zh

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/525Tumor necrosis factor [TNF]
HK16112331.5A 2013-09-06 2016-10-26 獲取 結合肽的方法,產生該肽的過程,用所述方法/過程獲取的 結合肽以及該肽的用途 HK1223957A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL2011406A NL2011406C2 (en) 2013-09-06 2013-09-06 Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides.
PCT/NL2014/050612 WO2015034364A1 (en) 2013-09-06 2014-09-05 Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides

Publications (1)

Publication Number Publication Date
HK1223957A1 true HK1223957A1 (zh) 2017-08-11

Family

ID=50190641

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16112331.5A HK1223957A1 (zh) 2013-09-06 2016-10-26 獲取 結合肽的方法,產生該肽的過程,用所述方法/過程獲取的 結合肽以及該肽的用途

Country Status (10)

Country Link
US (3) US10107821B2 (zh)
EP (1) EP3041867B1 (zh)
JP (3) JP2016538319A (zh)
CN (1) CN105531290B (zh)
AU (1) AU2014315744B2 (zh)
CA (1) CA2923494C (zh)
ES (1) ES2763428T3 (zh)
HK (1) HK1223957A1 (zh)
NL (1) NL2011406C2 (zh)
WO (1) WO2015034364A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2845927A1 (en) 2013-09-04 2015-03-11 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Electrochemical production of hydrogen peroxide
NL2011406C2 (en) 2013-09-06 2015-03-10 Bionovion Holding B V Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides.
DK3380522T3 (da) 2015-11-25 2024-01-22 Visterra Inc Antistofmolekyler til april og anvendelser deraf
IL259931B2 (en) 2015-12-16 2024-02-01 Gritstone Bio Inc Identification of neo-antigens, preparation, and use
WO2019036055A2 (en) 2017-08-18 2019-02-21 Ignite Biosciences, Inc. METHODS OF SELECTING BINDING REAGENTS
AU2018348165A1 (en) 2017-10-10 2020-05-21 Gritstone Bio, Inc. Neoantigen identification using hotspots
KR20200090855A (ko) 2017-11-22 2020-07-29 그릿스톤 온콜로지, 인코포레이티드 신생항원에 대한 접합 에피토프 제시 감소
US20240092921A1 (en) 2022-04-25 2024-03-21 Visterra, Inc. Antibody molecules to april and uses thereof

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
ATE87659T1 (de) 1986-09-02 1993-04-15 Enzon Lab Inc Bindungsmolekuele mit einzelpolypeptidkette.
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
WO1988007089A1 (en) 1987-03-18 1988-09-22 Medical Research Council Altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
AU658374B2 (en) * 1990-09-14 1995-04-13 Biosite Diagnostics Incorporated Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
ATE297465T1 (de) 1991-11-25 2005-06-15 Enzon Inc Verfahren zur herstellung von multivalenten antigenbindenden proteinen
EP0792278B1 (en) 1994-11-07 2007-06-13 Human Genome Sciences, Inc. Tumor necrosis factor-gamma
US6171787B1 (en) 1997-06-26 2001-01-09 Abbott Laboratories Member of the TNF family useful for treatment and diagnosis of disease
CA2303615A1 (en) * 1997-09-12 1999-03-18 Jurg Tschopp April- a novel protein with growth effects
WO2001060397A1 (en) 2000-02-16 2001-08-23 Genentech, Inc. Uses of agonists and antagonists to modulate activity of tnf-related molecules
UA74798C2 (uk) 1999-10-06 2006-02-15 Байоджен Айдек Ма Інк. Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами
MXPA02011130A (es) 2000-05-12 2003-03-10 Amgen Inc Metodos y composiciones de materia que se refieren a april/g70, bcma, blys/agp-3, y taci.
WO2001096528A2 (en) 2000-06-15 2001-12-20 Human Genome Sciences, Inc. Human tumor necrosis factor delta and epsilon
US7189820B2 (en) * 2001-05-24 2007-03-13 Human Genome Sciences, Inc. Antibodies against tumor necrosis factor delta (APRIL)
CN1636067A (zh) 2001-08-03 2005-07-06 杰南技术公司 TACls和BR3多肽及其用途
WO2003080672A1 (en) 2002-03-22 2003-10-02 Aprogen, Inc. Humanized antibody and process for preparing same
WO2003086310A2 (en) 2002-04-12 2003-10-23 Ramot At Tel Aviv University Ltd. Prevention of brain inflammation as a result of induced autoimmune response
CA2554526A1 (en) 2004-01-29 2005-08-18 Genentech, Inc. Variants of the extracellular domain of bcma and uses thereof
WO2005120571A2 (en) 2004-06-07 2005-12-22 Ramot At Tel Aviv University Ltd. Method of passive immunization against disease or disorder characterized by amyloid aggregation with diminished risk of neuroinflammation
ATE407751T1 (de) 2004-07-15 2008-09-15 Sidel Participations Verfahren zum sortieren von behältern
MX2007000998A (es) 2004-07-30 2007-07-11 Rinat Neuroscience Corp Anticuerpos dirigidos peptido beta-amiloide y procedimientos que usan los mismos.
ATE500275T1 (de) * 2005-09-26 2011-03-15 Enzo Life Sciences Els Ag Antikörper gegen april als biomarker zur frühen prognose in lymphompatienten
US9168286B2 (en) 2005-10-13 2015-10-27 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive disease
UY30776A1 (es) 2006-12-21 2008-07-03 Medarex Inc Anticuerpos cd44
WO2008119042A2 (en) 2007-03-27 2008-10-02 Zymogenetics, Inc. Combination of blys inhibition and/or april inhibition and immunnosuppressants for treatment of autoimmune disease
US8003335B2 (en) * 2008-04-30 2011-08-23 Universite Paris-SUD11 Levels of APRIL in serum and use in diagnostic methods
EA201170028A1 (ru) 2008-07-02 2011-12-30 Эмерджент Продакт Дивелопмент Сиэтл, Ллс СВЯЗЫВАЮЩИЕ НЕСКОЛЬКО МИШЕНЕЙ БЕЛКИ, ОБЛАДАЮЩИЕ АНТАГОНИСТИЧЕСКИМ ДЕЙСТВИЕМ TNF-α
CN102239180B (zh) 2008-08-18 2014-12-31 辉瑞大药厂 抗ccr2抗体
MX2011002838A (es) 2008-09-19 2011-07-29 Medimmune Llc Anticuerpos contra homologos sonic hedgehog y usos de los mismos.
EP2403528B1 (en) 2009-03-02 2016-04-20 Aduro Biotech Holdings, Europe B.V. Antibodies against a proliferating inducing ligand (april)
CN101928345B (zh) 2010-06-21 2012-08-29 中国科学技术大学 一种人源化抗体及其人源化改造方法
NL2011406C2 (en) 2013-09-06 2015-03-10 Bionovion Holding B V Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides.
NL2014108B1 (en) 2015-01-09 2016-09-30 Aduro Biotech Holdings Europe B V Altered april binding antibodies.
AU2016343993A1 (en) 2015-10-28 2018-05-10 Aduro Biotech, Inc. Compositions and methods for activating "stimulator of interferon gene"-dependent signalling
DK3380522T3 (da) 2015-11-25 2024-01-22 Visterra Inc Antistofmolekyler til april og anvendelser deraf
TWI797073B (zh) 2016-01-25 2023-04-01 德商安美基研究(慕尼黑)公司 包含雙特異性抗體建構物之醫藥組合物
US11034768B2 (en) 2017-10-30 2021-06-15 Sanofi Biotechnology Methods for treating or preventing asthma by administering an IL-4R antagonist
CN110464842B (zh) 2018-05-11 2022-10-14 信达生物制药(苏州)有限公司 包含抗pcsk9抗体的制剂及其用途
WO2020144535A1 (en) 2019-01-08 2020-07-16 Aduro Biotech Holdings, Europe B.V. Methods and compositions for treatment of multiple myeloma
BR112022024262A2 (pt) 2020-05-29 2023-02-23 Chinook Therapeutics Inc Métodos de tratamento de nefropatia por iga com um anticorpo de ligação a april

Also Published As

Publication number Publication date
US11047864B2 (en) 2021-06-29
EP3041867B1 (en) 2019-10-16
JP2020182466A (ja) 2020-11-12
CN105531290B (zh) 2020-05-22
US11959924B2 (en) 2024-04-16
JP2016538319A (ja) 2016-12-08
US20160202267A1 (en) 2016-07-14
JP6724105B2 (ja) 2020-07-15
US20190170766A1 (en) 2019-06-06
NL2011406C2 (en) 2015-03-10
JP2019055957A (ja) 2019-04-11
US20210325404A1 (en) 2021-10-21
AU2014315744B2 (en) 2020-02-27
CN105531290A (zh) 2016-04-27
EP3041867A1 (en) 2016-07-13
CA2923494C (en) 2023-03-14
US10107821B2 (en) 2018-10-23
ES2763428T3 (es) 2020-05-28
CA2923494A1 (en) 2015-03-12
WO2015034364A1 (en) 2015-03-12
AU2014315744A1 (en) 2016-03-17

Similar Documents

Publication Publication Date Title
IL291446A (en) Anti-trop2 antibodies and methods for their production
IL245132A0 (en) Composite material, heat absorbing component and method for manufacturing the composite material
EP3135488C0 (en) COMPOSITE MATERIAL AND METHOD FOR PRODUCING THEREOF
PL3002322T3 (pl) Kompozyt grafenowy i sposób jego wytwarzania
EP3006415A4 (en) PROCESS FOR PRODUCING NANOCEMENT AND NANOCEMENT
EP2987649A4 (en) TIRES AND METHOD FOR THE PRODUCTION OF TIRES
EP2957316A4 (en) MICRO-NEEDLE DRUG CARRIER ASSEMBLY, AND METHOD OF MANUFACTURING THE SAME
EP2987650A4 (en) TIRE AND METHOD FOR PRODUCING THE SAME
EP2969998A4 (en) AERATED COMPOSITE MATERIALS, PROCESSES FOR THEIR PRODUCTION AND USES
HK1223957A1 (zh) 獲取 結合肽的方法,產生該肽的過程,用所述方法/過程獲取的 結合肽以及該肽的用途
HK1217314A1 (zh) 多層管及其製造方法
EP3023391A4 (en) COMPOSITE NICKEL MANGANIC OXIDE HYDROXIDE, MANUFACTURING METHOD AND USE THEREOF
HK1209324A1 (zh) 納米酶、製備納米酶的方法、以及使用納米酶的方法
SG11201509964UA (en) Retainer, method for producing same and use thereof
EP3045511A4 (en) Near-infrared mechanoluminescent material, near-infrared mechanoluminescent object, and process for producing near-infrared mechanoluminescent material
EP2990413A4 (en) POROUS POLYPEPTIDE BODY AND PROCESS FOR PRODUCING THE SAME
EP2941451A4 (en) POLYMERS, ARTICLES WITH POLYMERS AND METHOD FOR THE PRODUCTION AND USE THEREOF
HUE053223T2 (hu) L-izoleucint termelõ mikroorganizmus és eljárás L-izoleucin elõállítására annak alkalmazásával
PL3040074T3 (pl) Preparat iniekcyjny i sposób jego wytwarzania
IL250451A0 (en) Anti-vasa antibodies, and methods for their preparation and use
SI2978793T1 (sl) Ognjeodporen poliamid, postopek za njegovo pripravo, kot tudi njegova uporaba
SG11201610858RA (en) Metallic microstructures with reduced-visibility and methods for producing same
HK1220727A1 (zh) 使用綿羊 細胞產生抗體的方法及其用途
EP2965774A4 (en) METHOD FOR PRODUCING AN OUTER TUBE EQUIPPED WITH A NEEDLE AND OUTER TUBE EQUIPPED WITH A NEEDLE
PL3124026T3 (pl) Preparat iniekcyjny i sposób jego wytwarzania