HK1223957A1 - 獲取 結合肽的方法,產生該肽的過程,用所述方法/過程獲取的 結合肽以及該肽的用途 - Google Patents
獲取 結合肽的方法,產生該肽的過程,用所述方法/過程獲取的 結合肽以及該肽的用途Info
- Publication number
- HK1223957A1 HK1223957A1 HK16112331.5A HK16112331A HK1223957A1 HK 1223957 A1 HK1223957 A1 HK 1223957A1 HK 16112331 A HK16112331 A HK 16112331A HK 1223957 A1 HK1223957 A1 HK 1223957A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- april
- binding peptides
- peptides
- producing
- obtaining
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/525—Tumor necrosis factor [TNF]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL2011406A NL2011406C2 (en) | 2013-09-06 | 2013-09-06 | Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides. |
PCT/NL2014/050612 WO2015034364A1 (en) | 2013-09-06 | 2014-09-05 | Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1223957A1 true HK1223957A1 (zh) | 2017-08-11 |
Family
ID=50190641
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16112331.5A HK1223957A1 (zh) | 2013-09-06 | 2016-10-26 | 獲取 結合肽的方法,產生該肽的過程,用所述方法/過程獲取的 結合肽以及該肽的用途 |
Country Status (10)
Country | Link |
---|---|
US (3) | US10107821B2 (zh) |
EP (1) | EP3041867B1 (zh) |
JP (3) | JP2016538319A (zh) |
CN (1) | CN105531290B (zh) |
AU (1) | AU2014315744B2 (zh) |
CA (1) | CA2923494C (zh) |
ES (1) | ES2763428T3 (zh) |
HK (1) | HK1223957A1 (zh) |
NL (1) | NL2011406C2 (zh) |
WO (1) | WO2015034364A1 (zh) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2845927A1 (en) | 2013-09-04 | 2015-03-11 | Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO | Electrochemical production of hydrogen peroxide |
NL2011406C2 (en) | 2013-09-06 | 2015-03-10 | Bionovion Holding B V | Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides. |
DK3380522T3 (da) | 2015-11-25 | 2024-01-22 | Visterra Inc | Antistofmolekyler til april og anvendelser deraf |
IL259931B2 (en) | 2015-12-16 | 2024-02-01 | Gritstone Bio Inc | Identification of neo-antigens, preparation, and use |
WO2019036055A2 (en) | 2017-08-18 | 2019-02-21 | Ignite Biosciences, Inc. | METHODS OF SELECTING BINDING REAGENTS |
AU2018348165A1 (en) | 2017-10-10 | 2020-05-21 | Gritstone Bio, Inc. | Neoantigen identification using hotspots |
KR20200090855A (ko) | 2017-11-22 | 2020-07-29 | 그릿스톤 온콜로지, 인코포레이티드 | 신생항원에 대한 접합 에피토프 제시 감소 |
US20240092921A1 (en) | 2022-04-25 | 2024-03-21 | Visterra, Inc. | Antibody molecules to april and uses thereof |
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US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
ATE87659T1 (de) | 1986-09-02 | 1993-04-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
WO1988007089A1 (en) | 1987-03-18 | 1988-09-22 | Medical Research Council | Altered antibodies |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
AU658374B2 (en) * | 1990-09-14 | 1995-04-13 | Biosite Diagnostics Incorporated | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
ATE297465T1 (de) | 1991-11-25 | 2005-06-15 | Enzon Inc | Verfahren zur herstellung von multivalenten antigenbindenden proteinen |
EP0792278B1 (en) | 1994-11-07 | 2007-06-13 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
US6171787B1 (en) | 1997-06-26 | 2001-01-09 | Abbott Laboratories | Member of the TNF family useful for treatment and diagnosis of disease |
CA2303615A1 (en) * | 1997-09-12 | 1999-03-18 | Jurg Tschopp | April- a novel protein with growth effects |
WO2001060397A1 (en) | 2000-02-16 | 2001-08-23 | Genentech, Inc. | Uses of agonists and antagonists to modulate activity of tnf-related molecules |
UA74798C2 (uk) | 1999-10-06 | 2006-02-15 | Байоджен Айдек Ма Інк. | Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами |
MXPA02011130A (es) | 2000-05-12 | 2003-03-10 | Amgen Inc | Metodos y composiciones de materia que se refieren a april/g70, bcma, blys/agp-3, y taci. |
WO2001096528A2 (en) | 2000-06-15 | 2001-12-20 | Human Genome Sciences, Inc. | Human tumor necrosis factor delta and epsilon |
US7189820B2 (en) * | 2001-05-24 | 2007-03-13 | Human Genome Sciences, Inc. | Antibodies against tumor necrosis factor delta (APRIL) |
CN1636067A (zh) | 2001-08-03 | 2005-07-06 | 杰南技术公司 | TACls和BR3多肽及其用途 |
WO2003080672A1 (en) | 2002-03-22 | 2003-10-02 | Aprogen, Inc. | Humanized antibody and process for preparing same |
WO2003086310A2 (en) | 2002-04-12 | 2003-10-23 | Ramot At Tel Aviv University Ltd. | Prevention of brain inflammation as a result of induced autoimmune response |
CA2554526A1 (en) | 2004-01-29 | 2005-08-18 | Genentech, Inc. | Variants of the extracellular domain of bcma and uses thereof |
WO2005120571A2 (en) | 2004-06-07 | 2005-12-22 | Ramot At Tel Aviv University Ltd. | Method of passive immunization against disease or disorder characterized by amyloid aggregation with diminished risk of neuroinflammation |
ATE407751T1 (de) | 2004-07-15 | 2008-09-15 | Sidel Participations | Verfahren zum sortieren von behältern |
MX2007000998A (es) | 2004-07-30 | 2007-07-11 | Rinat Neuroscience Corp | Anticuerpos dirigidos peptido beta-amiloide y procedimientos que usan los mismos. |
ATE500275T1 (de) * | 2005-09-26 | 2011-03-15 | Enzo Life Sciences Els Ag | Antikörper gegen april als biomarker zur frühen prognose in lymphompatienten |
US9168286B2 (en) | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
UY30776A1 (es) | 2006-12-21 | 2008-07-03 | Medarex Inc | Anticuerpos cd44 |
WO2008119042A2 (en) | 2007-03-27 | 2008-10-02 | Zymogenetics, Inc. | Combination of blys inhibition and/or april inhibition and immunnosuppressants for treatment of autoimmune disease |
US8003335B2 (en) * | 2008-04-30 | 2011-08-23 | Universite Paris-SUD11 | Levels of APRIL in serum and use in diagnostic methods |
EA201170028A1 (ru) | 2008-07-02 | 2011-12-30 | Эмерджент Продакт Дивелопмент Сиэтл, Ллс | СВЯЗЫВАЮЩИЕ НЕСКОЛЬКО МИШЕНЕЙ БЕЛКИ, ОБЛАДАЮЩИЕ АНТАГОНИСТИЧЕСКИМ ДЕЙСТВИЕМ TNF-α |
CN102239180B (zh) | 2008-08-18 | 2014-12-31 | 辉瑞大药厂 | 抗ccr2抗体 |
MX2011002838A (es) | 2008-09-19 | 2011-07-29 | Medimmune Llc | Anticuerpos contra homologos sonic hedgehog y usos de los mismos. |
EP2403528B1 (en) | 2009-03-02 | 2016-04-20 | Aduro Biotech Holdings, Europe B.V. | Antibodies against a proliferating inducing ligand (april) |
CN101928345B (zh) | 2010-06-21 | 2012-08-29 | 中国科学技术大学 | 一种人源化抗体及其人源化改造方法 |
NL2011406C2 (en) | 2013-09-06 | 2015-03-10 | Bionovion Holding B V | Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides. |
NL2014108B1 (en) | 2015-01-09 | 2016-09-30 | Aduro Biotech Holdings Europe B V | Altered april binding antibodies. |
AU2016343993A1 (en) | 2015-10-28 | 2018-05-10 | Aduro Biotech, Inc. | Compositions and methods for activating "stimulator of interferon gene"-dependent signalling |
DK3380522T3 (da) | 2015-11-25 | 2024-01-22 | Visterra Inc | Antistofmolekyler til april og anvendelser deraf |
TWI797073B (zh) | 2016-01-25 | 2023-04-01 | 德商安美基研究(慕尼黑)公司 | 包含雙特異性抗體建構物之醫藥組合物 |
US11034768B2 (en) | 2017-10-30 | 2021-06-15 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an IL-4R antagonist |
CN110464842B (zh) | 2018-05-11 | 2022-10-14 | 信达生物制药(苏州)有限公司 | 包含抗pcsk9抗体的制剂及其用途 |
WO2020144535A1 (en) | 2019-01-08 | 2020-07-16 | Aduro Biotech Holdings, Europe B.V. | Methods and compositions for treatment of multiple myeloma |
BR112022024262A2 (pt) | 2020-05-29 | 2023-02-23 | Chinook Therapeutics Inc | Métodos de tratamento de nefropatia por iga com um anticorpo de ligação a april |
-
2013
- 2013-09-06 NL NL2011406A patent/NL2011406C2/en not_active IP Right Cessation
-
2014
- 2014-09-05 EP EP14777903.7A patent/EP3041867B1/en active Active
- 2014-09-05 ES ES14777903T patent/ES2763428T3/es active Active
- 2014-09-05 JP JP2016540838A patent/JP2016538319A/ja not_active Ceased
- 2014-09-05 WO PCT/NL2014/050612 patent/WO2015034364A1/en active Application Filing
- 2014-09-05 CN CN201480049300.7A patent/CN105531290B/zh active Active
- 2014-09-05 AU AU2014315744A patent/AU2014315744B2/en active Active
- 2014-09-05 US US14/916,962 patent/US10107821B2/en active Active
- 2014-09-05 CA CA2923494A patent/CA2923494C/en active Active
-
2016
- 2016-10-26 HK HK16112331.5A patent/HK1223957A1/zh unknown
-
2018
- 2018-09-11 US US16/128,416 patent/US11047864B2/en active Active
- 2018-11-01 JP JP2018206560A patent/JP6724105B2/ja active Active
-
2020
- 2020-06-24 JP JP2020108855A patent/JP2020182466A/ja active Pending
-
2021
- 2021-06-28 US US17/360,719 patent/US11959924B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US11047864B2 (en) | 2021-06-29 |
EP3041867B1 (en) | 2019-10-16 |
JP2020182466A (ja) | 2020-11-12 |
CN105531290B (zh) | 2020-05-22 |
US11959924B2 (en) | 2024-04-16 |
JP2016538319A (ja) | 2016-12-08 |
US20160202267A1 (en) | 2016-07-14 |
JP6724105B2 (ja) | 2020-07-15 |
US20190170766A1 (en) | 2019-06-06 |
NL2011406C2 (en) | 2015-03-10 |
JP2019055957A (ja) | 2019-04-11 |
US20210325404A1 (en) | 2021-10-21 |
AU2014315744B2 (en) | 2020-02-27 |
CN105531290A (zh) | 2016-04-27 |
EP3041867A1 (en) | 2016-07-13 |
CA2923494C (en) | 2023-03-14 |
US10107821B2 (en) | 2018-10-23 |
ES2763428T3 (es) | 2020-05-28 |
CA2923494A1 (en) | 2015-03-12 |
WO2015034364A1 (en) | 2015-03-12 |
AU2014315744A1 (en) | 2016-03-17 |
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