HK1219476A1 - -山梨醇、 -脫氧- 二甲胺基 -、 -氨基- -二氟吡啶- -基 -氯- -氟- -二氫- -羥基氮雜環丁烷- -基 -氧代-喹啉羧酸的晶型 - Google Patents

-山梨醇、 -脫氧- 二甲胺基 -、 -氨基- -二氟吡啶- -基 -氯- -氟- -二氫- -羥基氮雜環丁烷- -基 -氧代-喹啉羧酸的晶型

Info

Publication number
HK1219476A1
HK1219476A1 HK16107424.3A HK16107424A HK1219476A1 HK 1219476 A1 HK1219476 A1 HK 1219476A1 HK 16107424 A HK16107424 A HK 16107424A HK 1219476 A1 HK1219476 A1 HK 1219476A1
Authority
HK
Hong Kong
Prior art keywords
quinolinecarboxylate
difluoropyridine
hydroxyazetidin
glucitol
deoxy
Prior art date
Application number
HK16107424.3A
Other languages
English (en)
Inventor
Hansenlmann Roger
M Reeve Maxwell
Original Assignee
Melinta Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melinta Therapeutics Inc filed Critical Melinta Therapeutics Inc
Publication of HK1219476A1 publication Critical patent/HK1219476A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK16107424.3A 2013-03-08 2016-06-24 -山梨醇、 -脫氧- 二甲胺基 -、 -氨基- -二氟吡啶- -基 -氯- -氟- -二氫- -羥基氮雜環丁烷- -基 -氧代-喹啉羧酸的晶型 HK1219476A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361775089P 2013-03-08 2013-03-08
PCT/US2014/021946 WO2014138639A1 (en) 2013-03-08 2014-03-07 Crystalline forms of d-glucitol, 1-deoxy-1-(methylamino)-, 1-(6-amino-3, 5-difluoropyridine-2-yl)-8-chloro-6-fluoro-1, 4-dihydro-7-(3-hydroxyazetidin-1-yl)-4-oxo-3-quinolinecarboxylate

Publications (1)

Publication Number Publication Date
HK1219476A1 true HK1219476A1 (zh) 2017-04-07

Family

ID=51492015

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16107424.3A HK1219476A1 (zh) 2013-03-08 2016-06-24 -山梨醇、 -脫氧- 二甲胺基 -、 -氨基- -二氟吡啶- -基 -氯- -氟- -二氫- -羥基氮雜環丁烷- -基 -氧代-喹啉羧酸的晶型

Country Status (14)

Country Link
US (1) US20160046603A1 (zh)
EP (1) EP2964652A4 (zh)
JP (1) JP2016511273A (zh)
CN (1) CN105189513A (zh)
AR (1) AR095203A1 (zh)
AU (1) AU2014225392A1 (zh)
BR (1) BR112015021725A2 (zh)
CA (1) CA2903755A1 (zh)
EA (1) EA201591668A1 (zh)
HK (1) HK1219476A1 (zh)
IL (1) IL241045A0 (zh)
MX (1) MX2015011651A (zh)
TW (1) TW201514165A (zh)
WO (1) WO2014138639A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105693695A (zh) * 2014-11-24 2016-06-22 重庆医药工业研究院有限责任公司 一种德拉沙星葡甲胺盐的晶型及其制备方法
CN105017223B (zh) * 2015-07-08 2017-08-01 扬子江药业集团有限公司 德拉沙星葡甲胺晶型i及其制备方法
CN105017224A (zh) * 2015-07-10 2015-11-04 扬子江药业集团有限公司 一种德拉沙星葡甲胺晶型的制备方法
CN106916142A (zh) * 2015-12-25 2017-07-04 江苏奥赛康药业股份有限公司 一种制备高纯度德拉沙星的方法
CN110467600A (zh) * 2018-05-10 2019-11-19 上海度德医药科技有限公司 一种德拉沙星葡甲胺盐晶型l及其制备方法
CN113018268B (zh) * 2019-12-25 2024-02-02 鲁南制药集团股份有限公司 一种注射用德拉沙星葡甲胺冻干制剂及其制备方法
WO2022240897A1 (en) * 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57134482A (en) * 1981-02-13 1982-08-19 Dainippon Pharmaceut Co Ltd 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8- naphthyridine-3-carboxylic acid-3/2 hydrate and its preparation
HUE056718T2 (hu) * 2004-10-08 2022-03-28 Abbvie Inc Hatóanyag (delafloxacin) meglumin sója és ennek kristályos formái
US20070238719A1 (en) * 2005-05-10 2007-10-11 Hopkins Scott J Method for reducing the risk of or preventing infection due to surgical or invasive medical procedures
US8129533B2 (en) * 2005-09-28 2012-03-06 Dalichi Sankyo Company, Limited Method for production of quinolone-containing lyophilized preparation
WO2008085913A1 (en) * 2007-01-04 2008-07-17 Rib-X Pharmaceuticals, Inc. Methods for treating, preventing, or reducing the risk of opthalmic, otic, and nasal infections
JP6063123B2 (ja) * 2008-11-15 2017-01-18 メリンタ セラピューティクス、インク 抗菌性組成物

Also Published As

Publication number Publication date
AU2014225392A1 (en) 2015-09-24
CN105189513A (zh) 2015-12-23
MX2015011651A (es) 2016-08-08
BR112015021725A2 (pt) 2017-07-18
TW201514165A (zh) 2015-04-16
EP2964652A4 (en) 2016-10-12
CA2903755A1 (en) 2014-09-12
EP2964652A1 (en) 2016-01-13
US20160046603A1 (en) 2016-02-18
IL241045A0 (en) 2015-11-30
WO2014138639A1 (en) 2014-09-12
JP2016511273A (ja) 2016-04-14
EA201591668A1 (ru) 2016-02-29
AR095203A1 (es) 2015-09-30

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