HK1221954A1 - β- -吡喃葡糖基 -吲哚化合物 - Google Patents

β- -吡喃葡糖基 -吲哚化合物

Info

Publication number
HK1221954A1
HK1221954A1 HK16110149.1A HK16110149A HK1221954A1 HK 1221954 A1 HK1221954 A1 HK 1221954A1 HK 16110149 A HK16110149 A HK 16110149A HK 1221954 A1 HK1221954 A1 HK 1221954A1
Authority
HK
Hong Kong
Prior art keywords
glucopyranosyl
beta
indole compounds
indole
compounds
Prior art date
Application number
HK16110149.1A
Other languages
English (en)
Inventor
Todd Fields
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HK1221954A1 publication Critical patent/HK1221954A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044—Pyrrole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HK16110149.1A 2013-10-17 2016-08-25 β- -吡喃葡糖基 -吲哚化合物 HK1221954A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361891995P 2013-10-17 2013-10-17
PCT/US2014/060882 WO2015057953A1 (en) 2013-10-17 2014-10-16 1 -(beta-d-glucopyranosyl)-1h-indole compounds

Publications (1)

Publication Number Publication Date
HK1221954A1 true HK1221954A1 (zh) 2017-06-16

Family

ID=51871285

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16110149.1A HK1221954A1 (zh) 2013-10-17 2016-08-25 β- -吡喃葡糖基 -吲哚化合物

Country Status (10)

Country Link
US (1) US9145435B2 (zh)
EP (1) EP3057971B1 (zh)
JP (1) JP6153670B2 (zh)
CN (1) CN105593229B (zh)
AR (1) AR097890A1 (zh)
CA (1) CA2923763C (zh)
ES (1) ES2711906T3 (zh)
HK (1) HK1221954A1 (zh)
TW (1) TWI633113B (zh)
WO (1) WO2015057953A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110128493B (zh) * 2018-02-08 2021-01-12 亚宝药业集团股份有限公司 吡喃糖取代杂环化合物的盐及其制备方法和用途
CN113121537B (zh) * 2021-04-13 2022-11-08 南通药明康德医药科技有限公司 一种2,8-二氮杂螺[4.5]癸烷-8-甲酸叔丁酯的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7425448B2 (en) 2001-07-12 2008-09-16 Geron Corporation Cardiomyocyte precursors from human embryonic stem cells
US20080139484A1 (en) * 2004-09-29 2008-06-12 Kissei Pharmaceutical Co., Ltd. 1(Beta-D-Glycopyranosyl)-3-Substituted Nitrogenous Heterocyclic Compound, Medicinal Composition Containing the Same, and Medicinal Use Thereof
TWI418556B (zh) 2006-07-27 2013-12-11 Mitsubishi Tanabe Pharma Corp 吲哚衍生物
UA113086C2 (xx) 2012-05-10 2016-12-12 Піразольні сполуки як інгібітори sglt1
TW201425326A (zh) * 2012-10-05 2014-07-01 Lilly Co Eli 新穎脲化合物

Also Published As

Publication number Publication date
TWI633113B (zh) 2018-08-21
CN105593229A (zh) 2016-05-18
EP3057971B1 (en) 2018-12-12
CA2923763A1 (en) 2015-04-23
WO2015057953A1 (en) 2015-04-23
CA2923763C (en) 2017-08-29
US9145435B2 (en) 2015-09-29
JP2016536355A (ja) 2016-11-24
EP3057971A1 (en) 2016-08-24
ES2711906T3 (es) 2019-05-08
CN105593229B (zh) 2017-07-25
US20150111846A1 (en) 2015-04-23
JP6153670B2 (ja) 2017-06-28
AR097890A1 (es) 2016-04-20
TW201605884A (zh) 2016-02-16

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