HK1219094A1 - 氟內酯衍生物配製過程 - Google Patents
氟內酯衍生物配製過程Info
- Publication number
- HK1219094A1 HK1219094A1 HK16105636.1A HK16105636A HK1219094A1 HK 1219094 A1 HK1219094 A1 HK 1219094A1 HK 16105636 A HK16105636 A HK 16105636A HK 1219094 A1 HK1219094 A1 HK 1219094A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- fluorolacton
- derivative
- preparation
- fluorolacton derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013070413 | 2013-01-14 | ||
| PCT/EP2014/050439 WO2014108525A1 (en) | 2013-01-14 | 2014-01-13 | Process for the preparation of a fluorolacton derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1219094A1 true HK1219094A1 (zh) | 2017-03-24 |
Family
ID=49989697
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16102911.4A HK1215020A1 (zh) | 2013-01-14 | 2016-03-14 | 製備氟代內酯衍生物的方法 |
| HK16105636.1A HK1219094A1 (zh) | 2013-01-14 | 2016-05-17 | 氟內酯衍生物配製過程 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16102911.4A HK1215020A1 (zh) | 2013-01-14 | 2016-03-14 | 製備氟代內酯衍生物的方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9624183B2 (zh) |
| EP (1) | EP2943475B1 (zh) |
| JP (1) | JP6317367B2 (zh) |
| KR (2) | KR20200138424A (zh) |
| AR (1) | AR094466A1 (zh) |
| BR (1) | BR112015016647A2 (zh) |
| CA (1) | CA2896253C (zh) |
| ES (1) | ES2655851T3 (zh) |
| HK (2) | HK1215020A1 (zh) |
| IL (1) | IL239697A (zh) |
| MX (1) | MX2015008661A (zh) |
| PT (1) | PT2943475T (zh) |
| RU (1) | RU2656600C2 (zh) |
| SG (1) | SG11201505455VA (zh) |
| WO (1) | WO2014108525A1 (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1633766B1 (en) | 2003-05-30 | 2019-03-06 | Gilead Pharmasset LLC | Modified fluorinated nucleoside analogues |
| AR094466A1 (es) | 2013-01-14 | 2015-08-05 | Hoffmann La Roche | Proceso para la obtención de un derivado de fluorlactona |
| CN105111169A (zh) * | 2015-07-08 | 2015-12-02 | 重庆沃肯精细化工有限公司 | 一种索菲布韦关键中间体的简便制备方法 |
| US10611739B2 (en) | 2016-08-16 | 2020-04-07 | Pharmaresources (Shanghai) Co., Ltd. | Process for preparation of lactone derivatives and intermediates thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101336247B (zh) | 2005-12-09 | 2013-01-23 | 豪夫迈·罗氏有限公司 | 抗病毒核苷 |
| CA2671856C (en) * | 2006-12-18 | 2015-02-10 | F. Hoffmann-La Roche Ag | Process for preparing 3,5-di-omicron-acyl-2-fluoro-2-c-methyl-d-ribono-gamma-lactone |
| WO2008090046A1 (en) * | 2007-01-23 | 2008-07-31 | F. Hoffmann-La Roche Ag | Alternate process for preparing 3,5-di-omicron-acyl-2-fluoro-2-c-methyl-d-ribono-gamma-lactone |
| AR094466A1 (es) | 2013-01-14 | 2015-08-05 | Hoffmann La Roche | Proceso para la obtención de un derivado de fluorlactona |
-
2014
- 2014-01-10 AR ARP140100100A patent/AR094466A1/es unknown
- 2014-01-13 KR KR1020207034457A patent/KR20200138424A/ko not_active Application Discontinuation
- 2014-01-13 WO PCT/EP2014/050439 patent/WO2014108525A1/en active Application Filing
- 2014-01-13 MX MX2015008661A patent/MX2015008661A/es unknown
- 2014-01-13 EP EP14700590.4A patent/EP2943475B1/en active Active
- 2014-01-13 KR KR1020157021634A patent/KR102187280B1/ko active IP Right Grant
- 2014-01-13 BR BR112015016647A patent/BR112015016647A2/pt not_active Application Discontinuation
- 2014-01-13 PT PT147005904T patent/PT2943475T/pt unknown
- 2014-01-13 RU RU2015130337A patent/RU2656600C2/ru not_active IP Right Cessation
- 2014-01-13 JP JP2015552063A patent/JP6317367B2/ja active Active
- 2014-01-13 CA CA2896253A patent/CA2896253C/en active Active
- 2014-01-13 ES ES14700590.4T patent/ES2655851T3/es active Active
- 2014-01-13 SG SG11201505455VA patent/SG11201505455VA/en unknown
-
2015
- 2015-06-29 IL IL239697A patent/IL239697A/en not_active IP Right Cessation
- 2015-07-14 US US14/798,879 patent/US9624183B2/en active Active
-
2016
- 2016-03-14 HK HK16102911.4A patent/HK1215020A1/zh unknown
- 2016-05-17 HK HK16105636.1A patent/HK1219094A1/zh unknown
-
2017
- 2017-03-09 US US15/454,561 patent/US9845299B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20170183317A1 (en) | 2017-06-29 |
| RU2015130337A (ru) | 2017-02-20 |
| AR094466A1 (es) | 2015-08-05 |
| CA2896253A1 (en) | 2014-07-17 |
| WO2014108525A1 (en) | 2014-07-17 |
| IL239697A (en) | 2017-12-31 |
| US9624183B2 (en) | 2017-04-18 |
| IL239697A0 (en) | 2015-08-31 |
| US20150315165A1 (en) | 2015-11-05 |
| EP2943475A1 (en) | 2015-11-18 |
| KR102187280B1 (ko) | 2020-12-07 |
| ES2655851T3 (es) | 2018-02-21 |
| BR112015016647A2 (pt) | 2017-07-11 |
| SG11201505455VA (en) | 2015-08-28 |
| MX2015008661A (es) | 2015-10-05 |
| KR20200138424A (ko) | 2020-12-09 |
| KR20150104205A (ko) | 2015-09-14 |
| RU2656600C2 (ru) | 2018-06-06 |
| HK1215020A1 (zh) | 2016-08-12 |
| US9845299B2 (en) | 2017-12-19 |
| JP6317367B2 (ja) | 2018-04-25 |
| PT2943475T (pt) | 2018-01-17 |
| EP2943475B1 (en) | 2017-10-25 |
| CA2896253C (en) | 2021-01-12 |
| JP2016508154A (ja) | 2016-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CHRG | Changes in the register |
Free format text: CORRECTION OF THE NAME OF APPLICANT FROM GILEAD SCIENCES, INC. TO GILEAD PHARMASSET LLC |