HK1217912A1 - 控釋肽製劑 - Google Patents

控釋肽製劑

Info

Publication number
HK1217912A1
HK1217912A1 HK16105940.2A HK16105940A HK1217912A1 HK 1217912 A1 HK1217912 A1 HK 1217912A1 HK 16105940 A HK16105940 A HK 16105940A HK 1217912 A1 HK1217912 A1 HK 1217912A1
Authority
HK
Hong Kong
Prior art keywords
controlled
peptide formulations
released peptide
released
formulations
Prior art date
Application number
HK16105940.2A
Other languages
English (en)
Inventor
Burton Kevin
Woehr Torsten
R Tice Thomas
Ayoub Mimoun
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of HK1217912A1 publication Critical patent/HK1217912A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HK16105940.2A 2008-08-29 2016-05-24 控釋肽製劑 HK1217912A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9325808P 2008-08-29 2008-08-29

Publications (1)

Publication Number Publication Date
HK1217912A1 true HK1217912A1 (zh) 2017-01-27

Family

ID=41266659

Family Applications (2)

Application Number Title Priority Date Filing Date
HK11111624.8A HK1157212A1 (zh) 2008-08-29 2011-10-27 控制釋放肽配方
HK16105940.2A HK1217912A1 (zh) 2008-08-29 2016-05-24 控釋肽製劑

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK11111624.8A HK1157212A1 (zh) 2008-08-29 2011-10-27 控制釋放肽配方

Country Status (14)

Country Link
US (2) US8951973B2 (zh)
EP (2) EP2331075B1 (zh)
JP (2) JP2012509251A (zh)
KR (1) KR101688666B1 (zh)
CN (2) CN102958512B (zh)
BR (1) BRPI0918820A2 (zh)
CA (1) CA2735581C (zh)
ES (1) ES2550308T3 (zh)
HK (2) HK1157212A1 (zh)
IL (2) IL211407A (zh)
MX (1) MX2011002255A (zh)
PL (1) PL2331075T3 (zh)
RU (2) RU2014150367A (zh)
WO (1) WO2010025435A2 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013406174B2 (en) * 2013-11-27 2017-06-15 Landmark Graphics Corporation Lumped data modeling of tool joint effects in underbalanced drilling
US20160106804A1 (en) 2014-10-15 2016-04-21 Yuhua Li Pharmaceutical composition with improved stability
JP6800372B2 (ja) * 2017-09-27 2020-12-16 ノベルファーマ株式会社Ｎｏｖｅｌ Ｐｈａｒｍａ Ｉｎｃ． 持続型パルミチン酸結合ＧｎＲＨ誘導体及びこれを含む薬剤学的組成物
AU2019437315B2 (en) 2019-03-26 2022-10-06 Novel Pharma Inc. Long-acting fatty acid-binding GnRH derivative and pharmaceutical composition comprising same
WO2022119401A1 (ko) * 2020-12-03 2022-06-09 바이오센서연구소 주식회사 경피 약물전달 효능이 향상된 펩타이드, 펩타이드 변형 방법 및 이에 의해 변형된 펩타이드를 포함하는 경피 약물전달용 조성물

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2209937B (en) 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
US5538739A (en) * 1989-07-07 1996-07-23 Sandoz Ltd. Sustained release formulations of water soluble peptides
JP3628713B2 (ja) 1993-06-07 2005-03-16 帝國製薬株式会社 生理学的に活性なペプチドを含有する膣投与製剤
JP2690276B2 (ja) * 1995-01-10 1997-12-10 科学技術振興事業団 静電結合型高分子ミセル薬物担体とその薬剤
US6515016B2 (en) 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
KR100321854B1 (ko) 1998-12-30 2002-08-28 동국제약 주식회사 루테이나이징 호르몬 릴리싱 호르몬 동족체를 함유하는 장기 서방출성 미립구 및 그의 제조방법
AU775905B2 (en) 1999-12-31 2004-08-19 Rutgers, The State University Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release
AU2000202A (en) 2000-10-31 2002-05-15 Pr Pharmaceuticals Inc Methods and compositions for enhanced delivery of bioactive molecules
US20040022861A1 (en) * 2001-01-30 2004-02-05 Williams Robert O. Process for production of nanoparticles and microparticles by spray freezing into liquid
DE10227232A1 (de) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
CA2533592C (en) 2003-07-23 2015-11-10 Pr Pharmaceuticals, Inc. Controlled release compositions
JP2006199590A (ja) * 2003-09-04 2006-08-03 Nano Career Kk 水溶性の塩基性薬物内包ナノ粒子含有組成物
US7291598B2 (en) * 2005-01-04 2007-11-06 Gp Medical, Inc. Nanoparticles for protein drug delivery
US20090326196A1 (en) * 2006-01-17 2009-12-31 Trustees Of Tufts College Proteins Containing a Fluorinated Amino Acid, and Methods of Using Same
DK1984009T3 (da) * 2006-01-18 2013-01-28 Qps Llc Farmaceutiske sammensætninger med forbedret stabilitet
CN106519025B (zh) * 2007-09-26 2021-04-23 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法

Also Published As

Publication number Publication date
CA2735581C (en) 2017-05-30
MX2011002255A (es) 2011-05-25
EP2331075B1 (en) 2015-07-29
US20150148295A1 (en) 2015-05-28
JP2012509251A (ja) 2012-04-19
CA2735581A1 (en) 2010-03-04
CN102958512B (zh) 2015-04-29
RU2543327C2 (ru) 2015-02-27
HK1157212A1 (zh) 2012-06-29
CN104873979A (zh) 2015-09-02
PL2331075T3 (pl) 2016-04-29
EP2946770A1 (en) 2015-11-25
IL236486A0 (en) 2015-02-26
CN102958512A (zh) 2013-03-06
IL211407A (en) 2016-11-30
WO2010025435A2 (en) 2010-03-04
KR20110070850A (ko) 2011-06-24
US20120027805A1 (en) 2012-02-02
IL211407A0 (en) 2011-05-31
RU2011111707A (ru) 2012-10-10
RU2014150367A (ru) 2015-06-27
ES2550308T3 (es) 2015-11-06
JP5945581B2 (ja) 2016-07-05
WO2010025435A3 (en) 2011-11-24
BRPI0918820A2 (pt) 2016-06-14
EP2331075A2 (en) 2011-06-15
KR101688666B1 (ko) 2016-12-21
US8951973B2 (en) 2015-02-10
JP2015057418A (ja) 2015-03-26

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