HK1216189A1 - 脂肪肝疾病的生物標誌物及其用法 - Google Patents

脂肪肝疾病的生物標誌物及其用法

Info

Publication number
HK1216189A1
HK1216189A1 HK16104033.3A HK16104033A HK1216189A1 HK 1216189 A1 HK1216189 A1 HK 1216189A1 HK 16104033 A HK16104033 A HK 16104033A HK 1216189 A1 HK1216189 A1 HK 1216189A1
Authority
HK
Hong Kong
Prior art keywords
biomarkers
methods
same
liver disease
fatty liver
Prior art date
Application number
HK16104033.3A
Other languages
English (en)
Inventor
Berger Alvin
Hu Yunfu
C Kalhan Satish
J Jr Mccreedy Bruce
Original Assignee
Metabolon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolon Inc filed Critical Metabolon Inc
Publication of HK1216189A1 publication Critical patent/HK1216189A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/08—Hepato-biliairy disorders other than hepatitis
    • G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/16—Phosphorus containing
    • Y10T436/163333—Organic [e.g., chemical warfare agents, insecticides, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
HK16104033.3A 2007-11-02 2016-04-08 脂肪肝疾病的生物標誌物及其用法 HK1216189A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98494207P 2007-11-02 2007-11-02
US4245908P 2008-04-04 2008-04-04

Publications (1)

Publication Number Publication Date
HK1216189A1 true HK1216189A1 (zh) 2016-10-21

Family

ID=40591773

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16104033.3A HK1216189A1 (zh) 2007-11-02 2016-04-08 脂肪肝疾病的生物標誌物及其用法

Country Status (6)

Country Link
US (3) US20100279956A1 (zh)
EP (3) EP2546649B1 (zh)
JP (1) JP5270684B2 (zh)
ES (1) ES2402142T3 (zh)
HK (1) HK1216189A1 (zh)
WO (1) WO2009059150A2 (zh)

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US8597875B2 (en) 2008-05-28 2013-12-03 Basf Se Method for diagnosing liver toxicity with sex specific biomarkers
WO2009153131A1 (en) * 2008-05-28 2009-12-23 Basf Se Means and methods for assessing liver enzyme induction
US20110256561A1 (en) * 2008-12-24 2011-10-20 The University Of Tokyo Liver disease marker, method and apparatus for measuring the same, and method for assaying pharmaceutical preparation
AU2010294193B2 (en) * 2009-09-11 2014-09-25 The Chinese University Of Hong Kong Methods for assessing liver pathologies
JP2011232164A (ja) * 2010-04-27 2011-11-17 Keio Gijuku 肝臓疾患マーカー、その測定方法、装置及び医薬品の検定方法
EP2863227B1 (en) 2010-06-10 2017-09-27 Metanomics Health GmbH Means and methods for metabolic differentiation of non-alcoholic steatohepatitis from liver disease
KR101867808B1 (ko) * 2010-06-18 2018-06-18 각고호우징 게이오기주크 간장질환 마커, 그 측정방법, 장치 및 의약품의 검정방법
US8728824B2 (en) 2011-06-22 2014-05-20 Quest Diagnostics Investments Inc. Mass spectrometric determination of fatty acids
JP6260275B2 (ja) * 2011-06-30 2018-01-17 味の素株式会社 脂肪肝の評価方法、脂肪肝評価装置、脂肪肝評価方法、脂肪肝評価プログラム、脂肪肝評価システム、および端末装置
WO2014043793A1 (en) * 2012-09-21 2014-03-27 The Governing Council Of The University Of Toronto Cmpf as a biomarker for diabetes and associated methods
CN107076753B (zh) * 2014-09-30 2019-01-18 深圳华大基因科技有限公司 肥胖人群特异性生物标志组合物及其用途
US20170370954A1 (en) * 2014-11-19 2017-12-28 Metabolon, Inc. Biomarkers for Fatty Liver Disease and Methods Using the Same
RU2617236C1 (ru) * 2015-12-02 2017-04-24 государственное бюджетное образовательное учреждение высшего профессионального образования "Северо-Западный государственный медицинский университет им. И.И. Мечникова" Министерства здравоохранения Российской Федерации Способ определения целесообразности проведения иммунологического обследования у пациентов неалкогольной жировой болезнью печени
WO2017210147A1 (en) * 2016-05-29 2017-12-07 Wei Jia Liver disease-related biomarkers and methods of use thereof
EP3502703A1 (en) 2017-12-22 2019-06-26 Metanomics Health GmbH Method for the assessment of nafld
CN109060977A (zh) * 2018-07-13 2018-12-21 深圳市绘云生物科技有限公司 用于肝纤维化和肝硬化诊断的生物标志物和试剂盒及使用方法
US11693005B2 (en) 2018-08-07 2023-07-04 Florida Atlantic University Board Of Trustees Methods for identifying treatments that reduce the actions of substances of abuse and addiction
WO2020066162A1 (ja) * 2018-09-26 2020-04-02 株式会社島津製作所 非アルコール性脂肪肝疾患の検出方法、非アルコール性脂肪肝疾患検出用キットおよび非アルコール性脂肪肝疾患検出用バイオマーカー
US20200241005A1 (en) * 2019-01-25 2020-07-30 Viscient Biosciences, Inc. Compositions and methods for the diagnosis and treatment of diseases of the liver
WO2021226042A1 (en) * 2020-05-04 2021-11-11 University Of Florida Research Foundation, Incorporated Biomarkers for assessing liver disease
US11754536B2 (en) 2021-11-01 2023-09-12 Matterworks Inc Methods and compositions for analyte quantification
CN116165385B (zh) * 2023-04-25 2023-07-18 南方医科大学南方医院 用于肝癌诊断的血清代谢标志物及其筛选方法和应用

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Also Published As

Publication number Publication date
JP2011503547A (ja) 2011-01-27
EP2546649A2 (en) 2013-01-16
EP2227689B1 (en) 2012-12-26
EP2930512A2 (en) 2015-10-14
US9977034B2 (en) 2018-05-22
EP2546649A3 (en) 2013-03-27
ES2402142T3 (es) 2013-04-29
EP2546649B1 (en) 2015-02-25
US20190120855A1 (en) 2019-04-25
EP2227689A4 (en) 2011-03-30
EP2227689A2 (en) 2010-09-15
EP2930512A3 (en) 2015-12-02
WO2009059150A3 (en) 2009-06-18
WO2009059150A2 (en) 2009-05-07
US20100279956A1 (en) 2010-11-04
US20150377910A1 (en) 2015-12-31
JP5270684B2 (ja) 2013-08-21
EP2930512B1 (en) 2018-01-31

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