HK1214772A1 - 生產二酮基呱嗪和含有二酮基呱嗪的組合物的方法 - Google Patents

生產二酮基呱嗪和含有二酮基呱嗪的組合物的方法 Download PDF

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Publication number
HK1214772A1
HK1214772A1 HK16102846.4A HK16102846A HK1214772A1 HK 1214772 A1 HK1214772 A1 HK 1214772A1 HK 16102846 A HK16102846 A HK 16102846A HK 1214772 A1 HK1214772 A1 HK 1214772A1
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HK
Hong Kong
Prior art keywords
dkp
albumin
diketopiperazines
methods
compositions
Prior art date
Application number
HK16102846.4A
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English (en)
Chinese (zh)
Inventor
David Bar-Or
Original Assignee
Ampio Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ampio Pharmaceuticals, Inc. filed Critical Ampio Pharmaceuticals, Inc.
Publication of HK1214772A1 publication Critical patent/HK1214772A1/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • A61K38/385Serum albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/06Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biomedical Technology (AREA)
HK16102846.4A 2013-02-01 2014-02-03 生產二酮基呱嗪和含有二酮基呱嗪的組合物的方法 HK1214772A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361759922P 2013-02-01 2013-02-01
US61/759,922 2013-02-01
PCT/US2014/014478 WO2014121210A1 (en) 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines

Publications (1)

Publication Number Publication Date
HK1214772A1 true HK1214772A1 (zh) 2016-08-05

Family

ID=51263032

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16102846.4A HK1214772A1 (zh) 2013-02-01 2014-02-03 生產二酮基呱嗪和含有二酮基呱嗪的組合物的方法

Country Status (15)

Country Link
US (1) US20150366932A1 (https=)
EP (1) EP2950811A4 (https=)
JP (1) JP6387019B2 (https=)
KR (1) KR20150114984A (https=)
CN (1) CN105188737A (https=)
AU (1) AU2014212095B2 (https=)
BR (1) BR112015017958A2 (https=)
CA (1) CA2900050A1 (https=)
EA (1) EA030414B1 (https=)
HK (1) HK1214772A1 (https=)
IL (1) IL240125A0 (https=)
MX (1) MX2015009908A (https=)
PH (1) PH12015501705A1 (https=)
SG (2) SG11201505715RA (https=)
WO (1) WO2014121210A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100553636C (zh) 2000-08-04 2009-10-28 Dmi生物科学公司 二酮基哌嗪和包含它们的组合物的使用方法
EP2517718B1 (en) 2003-05-15 2016-03-02 Ampio Pharmaceuticals, Inc. Treatment of T-cell mediated diseases
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ,インコーポレイテッド ジケトピペラジンを用いた医薬組成物
MY172699A (en) 2011-10-10 2019-12-10 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
EA028343B1 (ru) 2011-10-10 2017-11-30 Ампио Фармасьютикалз, Инк. Лечение дегенеративного заболевания сустава
EP2771007B1 (en) 2011-10-28 2018-04-04 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
BR112015020469A2 (pt) 2013-03-15 2020-01-28 Ampio Pharmaceuticals Inc Usos de da-dkp, composição e método para fornecimento de células-tronco a umindivíduo
RU2736513C2 (ru) 2014-08-18 2020-11-17 Ампио Фармасьютикалз, Инк. Лечение патологических состояний суставов
EP3310375A4 (en) 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES
US10426796B2 (en) * 2016-06-13 2019-10-01 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
US10456423B2 (en) 2016-06-13 2019-10-29 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
WO2021016186A1 (en) * 2019-07-19 2021-01-28 University Of Utah Research Foundation Rapid sperm separation based on sperm morphology and motility
US20230074374A1 (en) * 2020-02-16 2023-03-09 PUR Biologics, Inc Methods of manufacturing extracellular matrix using aspartyl alanyl diketopiperazine (da-dkp)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092556A5 (https=) * 1970-04-02 1972-01-21 Snam Progetti
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
US5811241A (en) * 1995-09-13 1998-09-22 Cortech, Inc. Method for preparing and identifying N-substitued 1,4-piperazines and N-substituted 1,4-piperazinediones
JP2000005569A (ja) * 1998-06-24 2000-01-11 Asahi Chem Ind Co Ltd 直列多段濾過法
CN100553636C (zh) * 2000-08-04 2009-10-28 Dmi生物科学公司 二酮基哌嗪和包含它们的组合物的使用方法
EP2517718B1 (en) * 2003-05-15 2016-03-02 Ampio Pharmaceuticals, Inc. Treatment of T-cell mediated diseases
CN1791420A (zh) * 2003-05-15 2006-06-21 Dmi生物科学公司 T-细胞介导的疾病的治疗
US7790039B2 (en) * 2003-11-24 2010-09-07 Northwest Biotherapeutics, Inc. Tangential flow filtration devices and methods for stem cell enrichment
US20050197496A1 (en) * 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
BRPI0514435B8 (pt) * 2004-08-20 2021-05-25 American Nat Red Cross isolamento sequêncial de proteínas e esquemas de purificação através de cromatografia por afinidade
EP2493921B1 (en) * 2009-10-30 2018-09-26 Albumedix Ltd Albumin variants
WO2012174472A1 (en) * 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
MY172699A (en) * 2011-10-10 2019-12-10 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
EA028343B1 (ru) * 2011-10-10 2017-11-30 Ампио Фармасьютикалз, Инк. Лечение дегенеративного заболевания сустава
EP2771007B1 (en) * 2011-10-28 2018-04-04 Ampio Pharmaceuticals, Inc. Treatment of rhinitis

Also Published As

Publication number Publication date
CA2900050A1 (en) 2014-08-07
EA201500783A1 (ru) 2016-05-31
AU2014212095B2 (en) 2018-07-26
SG10201706213RA (en) 2017-09-28
SG11201505715RA (en) 2015-08-28
WO2014121210A1 (en) 2014-08-07
US20150366932A1 (en) 2015-12-24
MX2015009908A (es) 2015-09-24
BR112015017958A2 (pt) 2017-07-11
AU2014212095A1 (en) 2015-09-10
KR20150114984A (ko) 2015-10-13
PH12015501705A1 (en) 2015-10-12
JP2016511238A (ja) 2016-04-14
EP2950811A1 (en) 2015-12-09
JP6387019B2 (ja) 2018-09-05
IL240125A0 (en) 2015-09-24
CN105188737A (zh) 2015-12-23
EA030414B1 (ru) 2018-08-31
EP2950811A4 (en) 2016-06-08

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