HK1214589A1 - 硝羥喹啉碱加成鹽及其用途 - Google Patents
硝羥喹啉碱加成鹽及其用途Info
- Publication number
- HK1214589A1 HK1214589A1 HK16102445.9A HK16102445A HK1214589A1 HK 1214589 A1 HK1214589 A1 HK 1214589A1 HK 16102445 A HK16102445 A HK 16102445A HK 1214589 A1 HK1214589 A1 HK 1214589A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- nitroxoline
- addition salts
- base addition
- base
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361790059P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/030532 WO2014145723A1 (en) | 2013-03-15 | 2014-03-17 | Base addition salts of nitroxoline and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1214589A1 true HK1214589A1 (zh) | 2016-07-29 |
Family
ID=51538074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16102445.9A HK1214589A1 (zh) | 2013-03-15 | 2016-03-02 | 硝羥喹啉碱加成鹽及其用途 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9758484B2 (zh) |
| EP (1) | EP2970128B1 (zh) |
| JP (1) | JP6273349B2 (zh) |
| KR (1) | KR20160021077A (zh) |
| CN (1) | CN105228984B (zh) |
| AU (2) | AU2014232722B2 (zh) |
| BR (1) | BR112015022849B1 (zh) |
| CA (1) | CA2907338C (zh) |
| ES (1) | ES2766758T3 (zh) |
| HK (1) | HK1214589A1 (zh) |
| MX (1) | MX357888B (zh) |
| WO (1) | WO2014145723A1 (zh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4029518A1 (en) * | 2016-03-31 | 2022-07-20 | Jiangsu Yahong Meditech Co., Ltd. | Combinational uses of nitroxoline and its analogues with chemotherapies and immunotherapies in the treatment of cancers |
| JP2022502510A (ja) * | 2018-09-29 | 2022-01-11 | 江▲蘇▼▲亞▼虹医▲薬▼科技股▲フン▼有限公司Jiangsu Yahong Meditech Co., Ltd | ニトロキソリンプロドラッグ及びその使用 |
| CN112402388A (zh) * | 2019-08-05 | 2021-02-26 | 江苏亚虹医药科技股份有限公司 | 一种用于治疗膀胱癌的口服固体制剂及其制备方法 |
| US20230000853A1 (en) * | 2019-12-31 | 2023-01-05 | Jiangsu Yahong Meditech Co., Ltd. | Pharmaceutical composition containing nitroxoline, nitroxoline tablet, preparation method therefor and use thereof |
| CN111773193A (zh) * | 2020-07-03 | 2020-10-16 | 江苏亚虹医药科技有限公司 | 含硝羟喹啉赖氨酸盐的药物组合物及其制备方法和用途 |
| CN111960998A (zh) * | 2020-08-03 | 2020-11-20 | 江苏亚虹医药科技有限公司 | 硝羟喹啉衍生物及其制备方法和用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2745834A (en) * | 1953-02-09 | 1956-05-15 | Phillips Petroleum Co | Stabilization of certain vinyl-pyridines, vinyl quinolines and vinyl-isoquinolines |
| US2745832A (en) * | 1954-03-08 | 1956-05-15 | Nuodex Products Co Inc | Metal quinolinolates and methods of making the same |
| US3872128A (en) * | 1972-03-08 | 1975-03-18 | Union Carbide Corp | Antimicrobial hydroxy quinoline, ethylene-acrylic polymer compositions |
| JPS5768831A (en) | 1980-10-17 | 1982-04-27 | Fuji Photo Film Co Ltd | Heat developable photosensitive material |
| JPS57101835A (en) | 1980-12-17 | 1982-06-24 | Fuji Photo Film Co Ltd | Thermodevelopable photosensitive material |
| US4329185A (en) | 1981-01-21 | 1982-05-11 | Dso "Pharmachim" | Method for the preparation of a biologically active polyamide net |
| US5242892A (en) | 1984-07-27 | 1993-09-07 | The Board Of Trustees Of The University Of Illinois | Chlorophyll biosynthesis modulators |
| JPH03284734A (ja) | 1990-03-31 | 1991-12-16 | Toshiba Corp | 有機非線形光学材料 |
| IT1317735B1 (it) | 2000-01-26 | 2003-07-15 | Nicox Sa | Sali di agenti antimicrobici. |
| JP2007514775A (ja) * | 2003-12-19 | 2007-06-07 | ライジェル ファーマシューティカルズ， インコーポレイテッド | １−（２，４−ピリミジンジアミノ）−２−シクロペンタンカルボキサイミド合成中間体の立体異性体および立体異性体混合物 |
| TWI328006B (en) * | 2003-12-26 | 2010-08-01 | Nissan Chemical Ind Ltd | Crystal form of quinoline compound and process for its production |
| US20080207673A1 (en) | 2005-05-04 | 2008-08-28 | Michel Xilinas | Method for Treating Cancer, Coronary, Inflammatory and Macular Disease, Combining the Modulation of Zinc-and/or Copper Dependent Proteins |
| ES2353814T3 (es) | 2005-05-11 | 2011-03-07 | Eth Zuerich | Proteinas n-glicosiladas recombinantes de celulas procariotas. |
| EP1892248A1 (en) | 2006-08-21 | 2008-02-27 | Eidgenössische Technische Hochschule Zürich | Specific and high affinity binding proteins comprising modified SH3 domains of FYN kinase |
| CN102239149B (zh) * | 2008-10-06 | 2015-05-13 | 约翰·霍普金斯大学 | 喹啉化合物作为血管新生、人类甲硫氨酰氨肽酶、以及sirt1的抑制剂,以及治疗病症的方法 |
| WO2010136105A2 (en) * | 2009-05-28 | 2010-12-02 | Merck Patent Gmbh | Ammoniumcarboxylates |
| JP2010070557A (ja) | 2009-12-17 | 2010-04-02 | Anacor Pharmaceuticals Inc | 加水分解抵抗性ホウ素含有治療薬および使用法 |
| EP2353599A1 (en) | 2010-01-28 | 2011-08-10 | University of Ljubljana | 8-hydroxyquinolines as inhibitors of cathepsin B |
| WO2013006105A1 (en) * | 2011-07-07 | 2013-01-10 | Telefonaktiebolaget L M Ericsson (Publ) | A method in a base station of a communication system for making a handover decision, base station, computer programs, and computer program products |
-
2014
- 2014-03-17 US US14/777,185 patent/US9758484B2/en active Active
- 2014-03-17 MX MX2015012720A patent/MX357888B/es active IP Right Grant
- 2014-03-17 WO PCT/US2014/030532 patent/WO2014145723A1/en active Application Filing
- 2014-03-17 CA CA2907338A patent/CA2907338C/en active Active
- 2014-03-17 KR KR1020157028976A patent/KR20160021077A/ko active Search and Examination
- 2014-03-17 EP EP14762230.2A patent/EP2970128B1/en active Active
- 2014-03-17 CN CN201480025681.5A patent/CN105228984B/zh active Active
- 2014-03-17 ES ES14762230T patent/ES2766758T3/es active Active
- 2014-03-17 JP JP2016503414A patent/JP6273349B2/ja active Active
- 2014-03-17 AU AU2014232722A patent/AU2014232722B2/en active Active
- 2014-03-17 BR BR112015022849-6A patent/BR112015022849B1/pt active IP Right Grant
-
2016
- 2016-03-02 HK HK16102445.9A patent/HK1214589A1/zh unknown
-
2017
- 2017-02-07 AU AU2017200820A patent/AU2017200820A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN105228984B (zh) | 2018-03-23 |
| EP2970128A4 (en) | 2016-11-30 |
| CA2907338C (en) | 2019-09-17 |
| US9758484B2 (en) | 2017-09-12 |
| EP2970128B1 (en) | 2019-12-04 |
| US20160031819A1 (en) | 2016-02-04 |
| EP2970128A1 (en) | 2016-01-20 |
| BR112015022849A2 (pt) | 2017-12-26 |
| JP2016514705A (ja) | 2016-05-23 |
| AU2014232722A1 (en) | 2015-09-24 |
| ES2766758T3 (es) | 2020-06-15 |
| BR112015022849B1 (pt) | 2020-02-18 |
| MX2015012720A (es) | 2016-06-21 |
| MX357888B (es) | 2018-07-27 |
| JP6273349B2 (ja) | 2018-01-31 |
| AU2014232722B2 (en) | 2017-03-09 |
| CA2907338A1 (en) | 2014-09-18 |
| WO2014145723A1 (en) | 2014-09-18 |
| CN105228984A (zh) | 2016-01-06 |
| AU2017200820A1 (en) | 2017-03-02 |
| KR20160021077A (ko) | 2016-02-24 |
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