HK1212897A1 - 使用穿心蓮內酯對阿爾茨海默氏病和認知缺損的治療 - Google Patents

使用穿心蓮內酯對阿爾茨海默氏病和認知缺損的治療

Info

Publication number
HK1212897A1
HK1212897A1 HK16100880.5A HK16100880A HK1212897A1 HK 1212897 A1 HK1212897 A1 HK 1212897A1 HK 16100880 A HK16100880 A HK 16100880A HK 1212897 A1 HK1212897 A1 HK 1212897A1
Authority
HK
Hong Kong
Prior art keywords
andrographolides
alzheimers
treatment
cognitive impairment
cognitive
Prior art date
Application number
HK16100880.5A
Other languages
English (en)
Inventor
Nibaldo C Inestrosa
Orozco Juan L Hankcke
Original Assignee
Innobioscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innobioscience Llc filed Critical Innobioscience Llc
Publication of HK1212897A1 publication Critical patent/HK1212897A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK16100880.5A 2013-04-22 2016-01-27 使用穿心蓮內酯對阿爾茨海默氏病和認知缺損的治療 HK1212897A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361814445P 2013-04-22 2013-04-22
PCT/US2014/034758 WO2014176149A1 (en) 2013-04-22 2014-04-21 Treatment of alzheimer's and cognitive impairment with andrographolides

Publications (1)

Publication Number Publication Date
HK1212897A1 true HK1212897A1 (zh) 2016-06-24

Family

ID=51792315

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16100880.5A HK1212897A1 (zh) 2013-04-22 2016-01-27 使用穿心蓮內酯對阿爾茨海默氏病和認知缺損的治療

Country Status (6)

Country Link
US (1) US20150352075A1 (zh)
EP (1) EP2897608B1 (zh)
ES (1) ES2702619T3 (zh)
HK (1) HK1212897A1 (zh)
PL (1) PL2897608T3 (zh)
WO (1) WO2014176149A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104861010B (zh) * 2014-11-27 2016-06-29 江西省药品检验检测研究院 一种新的劳丹烷型二萜苷化合物及其制备方法和用途
MY176459A (en) * 2016-05-23 2020-08-10 Univ Putra Malaysia Extract of andrographis paniculata for cognitive enhancement
CN109824655B (zh) * 2019-04-08 2021-09-24 沈阳药科大学 穿心莲内酯化合物及其制备方法和用途
US20220409573A1 (en) * 2021-06-11 2022-12-29 Innobioscience, Llc Hippocampus Regeneration And Memory Recovery

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001051659A2 (en) * 2000-01-13 2001-07-19 Genset Biallelic markers derived from genomic regions carrying genes involved in central nervous system disorders
KR20070026398A (ko) * 2004-02-03 2007-03-08 우니베르시다드 오스뜨랄 데 칠레 Ｐｐａｒ-감마 수용체의 활성화에 의한 자가면역 질환 및알츠하이머병의 치료에 유용한, 천심련으로부터 추출된랍단 디테르펜을 포함하는 조성물
CN1666985A (zh) * 2004-03-11 2005-09-14 和记黄埔医药企业有限公司 穿心莲内酯及其衍生物、类似物的医药用途
EP2066355A2 (en) * 2006-09-19 2009-06-10 Braincells, Inc. Combination comprising a peroxisome proliferator activated receptor agent and a second neurogenic agent for treating a nervous system disorder, increasing neurodifferentiation and increasing neurogenesis
US7601854B2 (en) * 2006-10-25 2009-10-13 Kang Jian Biotech Corp., Ltd. Diterpenes from the fruiting body of Antrodia camphorata and pharmaceutical compositions thereof
CN101371832B (zh) * 2007-08-20 2012-05-09 烟台靶点药物研究有限公司 三乙酰穿心莲内酯作为炎性细胞因子抑制剂的医药用途
IT1397386B1 (it) * 2010-01-12 2013-01-10 Indena Spa Composizioni a base di estratti di andrographis paniculata combinati con estratti di ginkgo biloba complessati con fosfolipidi e loro uso.
CN103224492B (zh) * 2013-04-15 2016-01-13 南京工业大学 14-芳基醚穿心莲內酯衍生物及其制备方法和应用

Also Published As

Publication number Publication date
WO2014176149A4 (en) 2014-12-04
ES2702619T3 (es) 2019-03-04
EP2897608B1 (en) 2018-08-22
US20150352075A1 (en) 2015-12-10
EP2897608A1 (en) 2015-07-29
EP2897608A4 (en) 2016-04-13
PL2897608T3 (pl) 2019-07-31
WO2014176149A1 (en) 2014-10-30

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