HK1212212A1 - 抑制缺氧誘導型轉錄因子復合體的活性的組合物和方法及其治療腫瘤的用途 - Google Patents

抑制缺氧誘導型轉錄因子復合體的活性的組合物和方法及其治療腫瘤的用途

Info

Publication number
HK1212212A1
HK1212212A1 HK16100091.0A HK16100091A HK1212212A1 HK 1212212 A1 HK1212212 A1 HK 1212212A1 HK 16100091 A HK16100091 A HK 16100091A HK 1212212 A1 HK1212212 A1 HK 1212212A1
Authority
HK
Hong Kong
Prior art keywords
hypoxia
tumors
compositions
treatment
methods
Prior art date
Application number
HK16100091.0A
Other languages
English (en)
Inventor
Bogdan Z Olenyuk
Ramin Dubey
Michael D Levin
Original Assignee
Univ Southern California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Southern California filed Critical Univ Southern California
Publication of HK1212212A1 publication Critical patent/HK1212212A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK16100091.0A 2012-08-29 2016-01-06 抑制缺氧誘導型轉錄因子復合體的活性的組合物和方法及其治療腫瘤的用途 HK1212212A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261694717P 2012-08-29 2012-08-29
PCT/US2013/032523 WO2014035484A1 (en) 2012-08-29 2013-03-15 Compositions and methods for inhibiting activity of hypoxia-inducible transcription factor complex and its use for treatment of tumors

Publications (1)

Publication Number Publication Date
HK1212212A1 true HK1212212A1 (zh) 2016-06-10

Family

ID=50184084

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16100091.0A HK1212212A1 (zh) 2012-08-29 2016-01-06 抑制缺氧誘導型轉錄因子復合體的活性的組合物和方法及其治療腫瘤的用途

Country Status (9)

Country Link
US (1) US9416145B2 (zh)
EP (2) EP3354655A1 (zh)
JP (1) JP6309523B2 (zh)
CN (1) CN104755084B (zh)
AU (1) AU2013309515B2 (zh)
CA (1) CA2883904C (zh)
ES (1) ES2655990T3 (zh)
HK (1) HK1212212A1 (zh)
WO (1) WO2014035484A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015095821A1 (en) * 2013-12-20 2015-06-25 Globavir Biosciences, Inc. Epidithiodiketopiperazine compounds, compositions, and methods
CN106974741B (zh) * 2017-03-23 2019-04-05 首都医科大学附属北京安贞医院 间歇性低氧系统在胸主动脉瘤治疗装置中的用途
KR102091730B1 (ko) * 2017-07-05 2020-03-23 바스테라 주식회사 에피디티오디옥소피페라진 화합물 또는 이의 유도체, 또는 이들의 약학적으로 허용가능한 염을 포함하는 폐동맥고혈압 예방 또는 치료용 약학적 조성물
US20220323453A1 (en) * 2019-08-28 2022-10-13 Vasthera Co. Ltd. Pharmaceutical composition for prevention or treatment of solid cancer comprising epidithiodioxopiperazine derivative or pharmaceutically acceptable salt thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728830A (en) 1993-09-22 1998-03-17 Kyowa Hakko Kogyo Co., Ltd. Farnesyltransferase inhibitor
GB9921477D0 (en) * 1999-09-10 1999-11-17 Inst Biomar Sa New active marine alkaloids
ITMI20042477A1 (it) * 2004-12-23 2005-03-23 Cell Therapeutics Europe Srl Uso di antibiotici a strutura dichetoditiopiperazinica per la preparazione di composizioni farmaceutiche antiangiogeniche
US20090264421A1 (en) * 2007-10-05 2009-10-22 Bible Keith C Methods and Compositions for Treating Cancer
CA2714226C (en) * 2008-02-07 2017-03-28 Marquette University Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings
US20090264427A1 (en) * 2008-04-16 2009-10-22 Wyeth 3-Cyanoquinolines, Methods for Preparation and Use as Insulin-like Growth Factor Inhibitors

Also Published As

Publication number Publication date
US20150246933A1 (en) 2015-09-03
ES2655990T3 (es) 2018-02-22
EP2890382B1 (en) 2017-10-25
JP2015526516A (ja) 2015-09-10
EP2890382A4 (en) 2016-03-23
CN104755084A (zh) 2015-07-01
CA2883904A1 (en) 2014-03-06
EP2890382A1 (en) 2015-07-08
WO2014035484A1 (en) 2014-03-06
AU2013309515B2 (en) 2018-06-28
CA2883904C (en) 2019-09-24
EP3354655A1 (en) 2018-08-01
CN104755084B (zh) 2018-04-03
JP6309523B2 (ja) 2018-04-11
US9416145B2 (en) 2016-08-16
AU2013309515A1 (en) 2015-03-19

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