HK1211919A1 - 抗病毒化合物的合成 - Google Patents
抗病毒化合物的合成Info
- Publication number
- HK1211919A1 HK1211919A1 HK15112626.0A HK15112626A HK1211919A1 HK 1211919 A1 HK1211919 A1 HK 1211919A1 HK 15112626 A HK15112626 A HK 15112626A HK 1211919 A1 HK1211919 A1 HK 1211919A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- synthesis
- antiviral compound
- antiviral
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261684543P | 2012-08-17 | 2012-08-17 | |
| US13/801,039 US8759544B2 (en) | 2012-08-17 | 2013-03-13 | Synthesis of an antiviral compound |
| PCT/US2013/054405 WO2014028342A1 (en) | 2012-08-17 | 2013-08-09 | Synthesis of an antiviral compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1211919A1 true HK1211919A1 (zh) | 2016-06-03 |
Family
ID=50100499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15112626.0A HK1211919A1 (zh) | 2012-08-17 | 2015-12-23 | 抗病毒化合物的合成 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8759544B2 (zh) |
| EP (1) | EP2885294B1 (zh) |
| JP (1) | JP6118412B2 (zh) |
| AU (1) | AU2013302913B2 (zh) |
| CA (1) | CA2882115A1 (zh) |
| ES (1) | ES2613552T3 (zh) |
| HK (1) | HK1211919A1 (zh) |
| PT (1) | PT2885294T (zh) |
| TW (1) | TW201420587A (zh) |
| WO (1) | WO2014028342A1 (zh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8841340B2 (en) | 2012-08-17 | 2014-09-23 | Gilead Sciences, Inc. | Solid forms of an antiviral compound |
| WO2016057931A1 (en) | 2014-10-10 | 2016-04-14 | The Research Foundation For The State University Of New York | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration |
| EP3454856A4 (en) | 2016-05-10 | 2019-12-25 | C4 Therapeutics, Inc. | HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
| EP3455218A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | C3 CARBON-BASED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
| WO2017197036A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
| JP7312882B2 (ja) | 2020-03-31 | 2023-07-21 | 本田技研工業株式会社 | 情報表示装置 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5861421A (en) | 1995-12-21 | 1999-01-19 | Smithkline Beecham Corporation | 4,4-(disubstituted) cyclohexan-1-one monomers and related compounds |
| US20020002199A1 (en) | 1998-03-12 | 2002-01-03 | Lone Jeppesen | Modulators of protein tyrosine phosphatases (ptpases) |
| US20050119332A1 (en) | 1998-03-12 | 2005-06-02 | Lone Jeppesen | Substituted thiophene compounds as modulators of protein tyrosine phosphatases (PTPases) |
| EP2206709A3 (en) | 2001-06-11 | 2011-06-29 | Virochem Pharma Inc. | Thiophene derivatives as antiviral agents for flavivirus infection |
| WO2002100846A1 (en) | 2001-06-11 | 2002-12-19 | Shire Biochem Inc. | Compounds and methods for the treatment or prevention of flavivirus infections |
| MXPA05006196A (es) | 2002-12-10 | 2006-01-27 | Virochem Pharma Inc | Compuestos y metodos para el tratamiento o prevencion de infecciones por flavivirus. |
| KR101058696B1 (ko) | 2002-12-10 | 2011-08-22 | 바이로켐 파마 인코포레이티드 | 후라비바이러스 감염의 치료 또는 예방을 위한 화합물과방법 |
| DE10359791A1 (de) | 2003-12-19 | 2005-07-21 | Bayer Healthcare Ag | Substituierte Thiophene |
| WO2005081954A2 (en) | 2004-02-25 | 2005-09-09 | Wyeth | Inhibitors of protein tyrosine phosphatase 1b |
| JP2007531757A (ja) | 2004-03-30 | 2007-11-08 | カイロン コーポレイション | 抗癌剤としての置換チオフェン誘導体 |
| DE102005028077A1 (de) | 2004-12-22 | 2006-07-13 | Aicuris Gmbh & Co. Kg | Alkinyl-substituierte Thiophene |
| DE102004061746A1 (de) | 2004-12-22 | 2006-07-06 | Bayer Healthcare Ag | Alkinyl-substituierte Thiophene |
| AP2007004245A0 (en) | 2005-05-13 | 2007-12-31 | Virochem Pharma Inc | Compounds and methods for the treatment or prevention of flavivirus infections |
| JP2009526794A (ja) | 2006-02-15 | 2009-07-23 | サノフィ−アベンティス | 新規なアミノアルコール置換アリールチエノピリミジノン、それらの製造方法及び薬剤としてそれらの使用 |
| EA201101492A1 (ru) | 2006-11-15 | 2012-09-28 | Вирокем Фарма Инк. | Аналоги тиофена для лечения или предупреждения флавивирусных инфекций |
| JP2010510191A (ja) | 2006-11-17 | 2010-04-02 | スミスクライン ビーチャム コーポレーション | 抗ウイルス剤としての２−カルボキシチオフェン誘導体 |
| KR20110098779A (ko) | 2008-12-03 | 2011-09-01 | 프레시디오 파마슈티칼스, 인코포레이티드 | Ｈｃｖ ｎｓ5ａ의 억제제 |
| AU2010276441B2 (en) | 2009-07-21 | 2015-07-02 | Gilead Sciences, Inc. | Inhibitors of Flaviviridae viruses |
| KR20120081123A (ko) | 2009-09-09 | 2012-07-18 | 길리애드 사이언시즈, 인코포레이티드 | 플라비비리대 바이러스의 억제제 |
| AU2010326225A1 (en) | 2009-11-25 | 2012-06-07 | Vertex Pharmaceuticals Incorporated | 5-alkynyl-thiophene-2-carboxylic acid derivatives and their use for the treatment or prevention of flavivirus infections |
| ES2543105T3 (es) | 2010-01-15 | 2015-08-14 | Gilead Sciences, Inc. | Inhibidores de virus flaviviridae |
| SG10201500298PA (en) | 2010-01-15 | 2015-03-30 | Gilead Sciences Inc | Inhibitors of flaviviridae viruses |
| WO2012006070A1 (en) * | 2010-06-28 | 2012-01-12 | Vertex Pharmaceuticals Incorporated | Compounds and methods for the treatment or prevention of flavivirus infections |
| AU2011276526A1 (en) | 2010-06-28 | 2013-01-10 | Vertex Pharmaceuticals Incorporated | Compounds and methods for the treatment or prevention of Flavivirus infections |
| WO2012087596A1 (en) | 2010-12-20 | 2012-06-28 | Gilead Sciences, Inc. | Combinations for treating hcv |
| EP2734515B1 (en) | 2011-07-13 | 2015-11-04 | Gilead Sciences, Inc. | Thiophen-2-carboxylic acid derivatives useful as inhibitors of flaviviridae viruses |
| US8927741B2 (en) | 2012-08-17 | 2015-01-06 | Gilead Sciences, Inc. | Synthesis of an antiviral compound |
| US8841340B2 (en) | 2012-08-17 | 2014-09-23 | Gilead Sciences, Inc. | Solid forms of an antiviral compound |
-
2013
- 2013-03-13 US US13/801,039 patent/US8759544B2/en active Active
- 2013-08-09 JP JP2015527505A patent/JP6118412B2/ja active Active
- 2013-08-09 CA CA2882115A patent/CA2882115A1/en not_active Abandoned
- 2013-08-09 ES ES13750249.8T patent/ES2613552T3/es active Active
- 2013-08-09 PT PT137502498T patent/PT2885294T/pt unknown
- 2013-08-09 WO PCT/US2013/054405 patent/WO2014028342A1/en active Application Filing
- 2013-08-09 AU AU2013302913A patent/AU2013302913B2/en not_active Ceased
- 2013-08-09 EP EP13750249.8A patent/EP2885294B1/en active Active
- 2013-08-13 TW TW102128977A patent/TW201420587A/zh unknown
-
2014
- 2014-05-06 US US14/271,216 patent/US9045462B2/en active Active
-
2015
- 2015-12-23 HK HK15112626.0A patent/HK1211919A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW201420587A (zh) | 2014-06-01 |
| JP2015530993A (ja) | 2015-10-29 |
| US8759544B2 (en) | 2014-06-24 |
| US20140051867A1 (en) | 2014-02-20 |
| ES2613552T3 (es) | 2017-05-24 |
| WO2014028342A1 (en) | 2014-02-20 |
| PT2885294T (pt) | 2017-02-09 |
| CA2882115A1 (en) | 2014-02-20 |
| US20140275570A1 (en) | 2014-09-18 |
| JP6118412B2 (ja) | 2017-04-19 |
| AU2013302913A1 (en) | 2015-02-05 |
| EP2885294B1 (en) | 2016-11-30 |
| US9045462B2 (en) | 2015-06-02 |
| AU2013302913B2 (en) | 2017-03-16 |
| EP2885294A1 (en) | 2015-06-24 |
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