HK1211916A1 - Arylalkylamine compounds as calcium sensing receptor modulators - Google Patents

Arylalkylamine compounds as calcium sensing receptor modulators

Info

Publication number
HK1211916A1
HK1211916A1 HK15112739.4A HK15112739A HK1211916A1 HK 1211916 A1 HK1211916 A1 HK 1211916A1 HK 15112739 A HK15112739 A HK 15112739A HK 1211916 A1 HK1211916 A1 HK 1211916A1
Authority
HK
Hong Kong
Prior art keywords
receptor modulators
sensing receptor
calcium sensing
arylalkylamine compounds
arylalkylamine
Prior art date
Application number
HK15112739.4A
Other languages
English (en)
Chinese (zh)
Inventor
Manojkumar Ramprasad Shukla
Vinod Dinkar Chaudhari
Ankush Gangaram Sarde
Ramesh Dattatraya Phadtare
Mahadeo Bhaskar Tryambake
Dronamraju Prameela
Sanjeev Anant Kulkarni
Venkata P Palle
Rajender Kumar Kamboj
Original Assignee
Lupin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lupin Ltd filed Critical Lupin Ltd
Publication of HK1211916A1 publication Critical patent/HK1211916A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/02Formation of carboxyl groups in compounds containing amino groups, e.g. by oxidation of amino alcohols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/26Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK15112739.4A 2012-08-27 2015-12-28 Arylalkylamine compounds as calcium sensing receptor modulators HK1211916A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN988KO2012 2012-08-27
IN1031KO2012 2012-09-10
PCT/IB2013/056840 WO2014033604A1 (en) 2012-08-27 2013-08-23 Arylalkylamine compounds as calcium sensing receptor modulators

Publications (1)

Publication Number Publication Date
HK1211916A1 true HK1211916A1 (en) 2016-06-03

Family

ID=54203597

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15112739.4A HK1211916A1 (en) 2012-08-27 2015-12-28 Arylalkylamine compounds as calcium sensing receptor modulators

Country Status (10)

Country Link
US (3) US9227919B2 (xx)
EP (1) EP2888225A1 (xx)
JP (1) JP2015528462A (xx)
CN (1) CN104583177B (xx)
AU (1) AU2013308081A1 (xx)
CA (1) CA2882039A1 (xx)
HK (1) HK1211916A1 (xx)
IN (1) IN2015MN00421A (xx)
WO (1) WO2014033604A1 (xx)
ZA (1) ZA201501053B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015528462A (ja) 2012-08-27 2015-09-28 ルピン・リミテッドLupin Limited カルシウム感知受容体モジュレーターとしてのアリールアルキルアミン化合物
AU2014313835A1 (en) * 2013-08-28 2016-03-03 Lupin Atlantis Holdings Sa Substituted naphthalene compounds as calcium sensing receptor modulators
KR102614466B1 (ko) * 2016-11-14 2023-12-14 비온디스 비.브이. 단일-보호된 알파, 오메가-디아미노 알칸의 제조 방법
MX2022007939A (es) 2019-12-27 2022-07-27 Lupin Ltd Composiciones farmaceuticas de moduladores de casr y metodos y usos de las mismas.

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100558698C (zh) * 1994-10-21 2009-11-11 Nps药物有限公司 钙受体活性化合物
UA55374C2 (uk) * 1994-10-21 2003-04-15 Нпс Фармасьютікалз, Інк Сполуки, що мають активність по відношенню до рецепторів кальцію
FR2809396B1 (fr) 2000-05-24 2005-10-14 Centre Nat Rech Scient Nouvelles molecules possedant une activite calcimimetique et leur mode de preparation
FR2812875B1 (fr) 2000-08-08 2003-12-12 Centre Nat Rech Scient Nouvelles diamines possedant une activite modulatrice des casr et leur mode de preparation
US7176322B2 (en) * 2002-05-23 2007-02-13 Amgen Inc. Calcium receptor modulating agents
US6908935B2 (en) * 2002-05-23 2005-06-21 Amgen Inc. Calcium receptor modulating agents
WO2004069793A2 (en) 2003-01-28 2004-08-19 Bristol-Myers Squibb Company Novel 2-substituted cyclic amines as calcium sensing receptor modulators
AU2004232604C1 (en) * 2003-04-23 2008-06-05 Japan Tobacco Inc. CaSR antagonists
GB0309440D0 (en) * 2003-04-25 2003-06-04 Lilly Co Eli Quinolone derivatives
WO2004106280A1 (ja) 2003-05-28 2004-12-09 Japan Tobacco Inc. CaSRアンタゴニスト
CN101175724B (zh) 2005-05-19 2011-12-07 安斯泰来制药有限公司 吡咯烷衍生物或其盐
MX2009003673A (es) 2006-10-04 2009-04-22 Pfizer Prod Inc Derivados de piridido[4,3-d]pirimidin-4(3h)-ona como antagonistas de los receptores de calcio.
CA2669635A1 (en) 2006-11-16 2008-05-22 Astellas Pharma Inc. Piperidine derivative or salt thereof
KR20100108348A (ko) 2007-11-23 2010-10-06 레오 파마 에이/에스 질병 치료용의 신규한 사이클릭 탄화수소 화합물
KR101700152B1 (ko) 2008-10-03 2017-01-26 이에이 파마 가부시키가이샤 CaSR 효능제
WO2010042642A1 (en) 2008-10-08 2010-04-15 Amgen Inc. Calcium receptor modulating agents
WO2010136037A1 (en) 2009-05-27 2010-12-02 Leo Pharma A/S Novel calcium sensing receptor modulating compounds and pharmaceutical use thereof
WO2010150837A1 (ja) 2009-06-25 2010-12-29 第一三共株式会社 インドリン誘導体
US20130261132A1 (en) 2010-11-26 2013-10-03 Leo Pharma A/S Calcium-sensing receptor-active compounds
US20130245084A1 (en) 2010-11-26 2013-09-19 Leo Pharma A/S Calcium-sensing receptor-active compounds
JP2014500882A (ja) 2010-11-26 2014-01-16 レオ ファーマ アクティーゼルスカブ カルシウム感知受容体活性化合物
CA2828415A1 (en) 2011-03-10 2012-09-13 Lupin Limited Substituted morpholines as modulators for the calcium sensing receptor
JP6033835B2 (ja) * 2011-03-18 2016-11-30 ルピン アトランティス ホールディングス エスエー カルシウム感知受容体モジュレーターとしてのベンゾ[b][1,4]オキサジン誘導体
HUE046172T2 (hu) * 2012-02-24 2020-02-28 Lupin Ltd Szubsztituált krománvegyületek mint kalcium-szenzor receptor modulátorok
JP2015528462A (ja) * 2012-08-27 2015-09-28 ルピン・リミテッドLupin Limited カルシウム感知受容体モジュレーターとしてのアリールアルキルアミン化合物

Also Published As

Publication number Publication date
JP2015528462A (ja) 2015-09-28
CA2882039A1 (en) 2014-03-06
AU2013308081A1 (en) 2015-02-26
CN104583177A (zh) 2015-04-29
US9227919B2 (en) 2016-01-05
ZA201501053B (en) 2016-01-27
WO2014033604A1 (en) 2014-03-06
US9598371B2 (en) 2017-03-21
US20150239827A1 (en) 2015-08-27
IN2015MN00421A (xx) 2015-09-04
EP2888225A1 (en) 2015-07-01
CN104583177B (zh) 2016-09-07
US20160075655A1 (en) 2016-03-17
US20170137371A1 (en) 2017-05-18

Similar Documents

Publication Publication Date Title
IL237212A (en) Amino derivatives of benzoimidazole carboxylic acid as receptor modulators for apj
GB201213700D0 (en) Receptor antagnists II
IL232112A0 (en) Transduced imidazopyrimidines as modulators of 1gpbar receptors
IL251897A0 (en) X-receptor modulators of the liver
ZA201306576B (en) Substituted morpholines as modulators for the calcium sensing receptor
ZA201306223B (en) Heteroaryl derivatives as alpha7 nachir modulators
HK1205117A1 (en) Substituted chroman compounds as calcium sensing receptor modulators
HK1206333A1 (en) Liver receptor modulators
IL235557A0 (en) Modulators of 17 gpr receptors
HK1211916A1 (en) Arylalkylamine compounds as calcium sensing receptor modulators
GB201223053D0 (en) Receptor
PT2820010T (pt) Monitorização de minerais preciosos