HK1210625A1 - Method for obtaining immuno-stimulatory dendritic cells - Google Patents

Method for obtaining immuno-stimulatory dendritic cells

Info

Publication number
HK1210625A1
HK1210625A1 HK15111384.4A HK15111384A HK1210625A1 HK 1210625 A1 HK1210625 A1 HK 1210625A1 HK 15111384 A HK15111384 A HK 15111384A HK 1210625 A1 HK1210625 A1 HK 1210625A1
Authority
HK
Hong Kong
Prior art keywords
dendritic cells
stimulatory dendritic
obtaining immuno
immuno
obtaining
Prior art date
Application number
HK15111384.4A
Other languages
English (en)
Chinese (zh)
Inventor
Karsten Henco
Gnter Bauer
Justin Duckworth
Adrian Hayday
Richard Edelson
Robert Tigelaar
Michael Girardi
Original Assignee
Transimmune Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transimmune Ag filed Critical Transimmune Ag
Publication of HK1210625A1 publication Critical patent/HK1210625A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/15Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4615Dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643Vertebrate antigens
    • A61K39/4644Cancer antigens
    • A61K39/464499Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/11Coculture with; Conditioned medium produced by blood or immune system cells
    • C12N2502/115Platelets, megakaryocytes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
    • C12N2506/115Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells from monocytes, from macrophages
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2521/00Culture process characterised by the use of hydrostatic pressure, flow or shear forces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2529/00Culture process characterised by the use of electromagnetic stimulation
    • C12N2529/10Stimulation by light

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK15111384.4A 2013-01-03 2015-11-18 Method for obtaining immuno-stimulatory dendritic cells HK1210625A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361748546P 2013-01-03 2013-01-03
GBGB1300049.2A GB201300049D0 (en) 2013-01-03 2013-01-03 Method for obtaining immuno-stimulatory dendritic cells
PCT/EP2014/050010 WO2014106629A1 (en) 2013-01-03 2014-01-02 Method for obtaining immuno-stimulatory dendritic cells

Publications (1)

Publication Number Publication Date
HK1210625A1 true HK1210625A1 (en) 2016-04-29

Family

ID=47747911

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15111384.4A HK1210625A1 (en) 2013-01-03 2015-11-18 Method for obtaining immuno-stimulatory dendritic cells

Country Status (13)

Country Link
US (2) US20160298082A1 (xx)
EP (2) EP2941483B1 (xx)
JP (1) JP6621665B2 (xx)
KR (3) KR20180128993A (xx)
CN (2) CN109161528A (xx)
AU (1) AU2014204344B2 (xx)
CA (2) CA2897109C (xx)
DK (1) DK2941483T3 (xx)
ES (1) ES2795926T3 (xx)
GB (1) GB201300049D0 (xx)
HK (1) HK1210625A1 (xx)
PL (1) PL2941483T3 (xx)
WO (1) WO2014106629A1 (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2764105T3 (es) 2011-10-17 2020-06-02 Massachusetts Inst Technology Administración intracelular
AU2014306423B2 (en) 2013-08-16 2019-04-18 Massachusetts Institute Of Technology Selective delivery of material to cells
EP3705570A1 (en) * 2014-02-10 2020-09-09 Institut Curie Use of mcoln-1 modulators to regulate cell migration
GB201413665D0 (en) * 2014-07-03 2014-09-17 Transimmune Ag And Yale University Method for obtaining globally activated monocytes
SG11201703044PA (en) 2014-10-31 2017-05-30 Massachusetts Inst Technology Delivery of biomolecules to immune cells
CN107002089B (zh) 2014-11-14 2021-09-07 麻省理工学院 化合物和组合物向细胞中的破坏和场实现的递送
WO2016115179A1 (en) 2015-01-12 2016-07-21 Massachusetts Institute Of Technology Gene editing through microfluidic delivery
GB201513278D0 (en) * 2015-07-03 2015-09-09 Transimmune Ag And Yale University Device and method for obtaining immunostimulatory antigen-presenting cells
EP3320082B1 (en) 2015-07-09 2023-05-24 Massachusetts Institute of Technology Delivery of materials to anucleate cells
CN105039256A (zh) * 2015-07-13 2015-11-11 中政道和(北京)生物科技有限公司 一种支气管镜下获取肿瘤组织进行树突细胞培养扩增方法
EP3344658B1 (en) 2015-09-02 2022-05-11 Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. Antibodies specific to human t-cell immunoglobulin and itim domain (tigit)
US20190345447A1 (en) * 2016-09-29 2019-11-14 Hadasit Medical Research Services And Development Ltd. Dendritic cell preparations, compositions thereof and methods of using same
KR102356510B1 (ko) * 2017-09-05 2022-02-08 메디진 이뮤노테라피스 게엠바하 수지상 세포 효능 분석
GB201715445D0 (en) * 2017-09-25 2017-11-08 Senzagen Ab Novel cell line and uses thereof
US11098093B2 (en) 2019-01-07 2021-08-24 Shattuck Labs, Inc. Heterodimeric proteins for modulating gamma delta T cells
MX2021008022A (es) 2019-01-07 2021-08-05 Shattuck Labs Inc Proteínas heterodiméricas para modular células t gamma delta.
CN112301057B (zh) * 2019-07-30 2023-02-21 上海市第一人民医院 一种重组腺相关病毒载体及其制备方法与应用
JP2023501538A (ja) * 2019-11-13 2023-01-18 ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト 感染の宿主rnaバイオマーカーの同定
WO2023006982A1 (en) 2021-07-29 2023-02-02 Transimmune Ag Methods for selectively reducing immunogenicity in a transplant
WO2023006971A1 (en) * 2021-07-29 2023-02-02 Transimmune Ag Selective tolerization - methods of selectively generating tolerogenic dendritic cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050158856A1 (en) * 1999-04-20 2005-07-21 Edelson Richard L. Methods for producing functional antigen presenting dendritic cells using biodegradable microparticles for delivery of antigenic materials
EP1176986B1 (en) 1999-04-20 2018-07-04 Yale University Differentiation of monocytes into functional dendritic cells
US7727523B2 (en) * 2001-08-13 2010-06-01 Yale University Method for suppressing immune system response to transplanted tissue or cells
PT1567155E (pt) * 2002-12-06 2011-01-28 Northwest Biotherapeutics Inc Administração de células dendríticas parcialmente amadurecidas in vitro para o tratamento de tumores
US8524495B2 (en) * 2007-05-16 2013-09-03 Yale University Methods for inducing the differentiation of blood monocytes into functional dendritic cells
CA2783731C (en) * 2009-12-11 2018-03-27 Atyr Pharma, Inc. Aminoacyl trna synthetases for modulating inflammation

Also Published As

Publication number Publication date
EP2941483B1 (en) 2020-03-04
EP3741843B1 (en) 2024-06-26
GB201300049D0 (en) 2013-02-20
PL2941483T3 (pl) 2020-09-21
US20220112462A1 (en) 2022-04-14
JP2016504912A (ja) 2016-02-18
AU2014204344A1 (en) 2015-07-02
CN109161528A (zh) 2019-01-08
EP2941483A1 (en) 2015-11-11
WO2014106629A1 (en) 2014-07-10
CA2897109C (en) 2023-03-28
KR20180128993A (ko) 2018-12-04
AU2014204344B2 (en) 2017-04-06
CN105008522A (zh) 2015-10-28
ES2795926T3 (es) 2020-11-25
JP6621665B2 (ja) 2019-12-18
CA2897109A1 (en) 2014-07-10
CA3187235A1 (en) 2014-07-10
US20160298082A1 (en) 2016-10-13
EP3741843A1 (en) 2020-11-25
DK2941483T3 (da) 2020-06-02
KR20150122638A (ko) 2015-11-02
KR20200043549A (ko) 2020-04-27

Similar Documents

Publication Publication Date Title
HK1210625A1 (en) Method for obtaining immuno-stimulatory dendritic cells
HK1213048A1 (zh) 用於實施多重化驗的改進方法
HK1223993A1 (zh) 製作物體的方法
IL241627B (en) A method for t-cell activation
HK1210626A1 (en) Method for obtaining immuno-suppressive dendritic cells
ZA201501833B (en) Method for obtaining 1-kestone
GB201309057D0 (en) Method
EP2980207A4 (en) CELL SORTING PROCESS
GB201315777D0 (en) Novel method
EP2957630A4 (en) UNDIFFERENCED CELL IMMUNIZATION PROCESS
EP3000876A4 (en) METHOD FOR PRODUCING NK CELLS
EP3000803A4 (en) PROCESS FOR PREPARING DIAMINO-DICYCLOHEXYL-METHANE
EP3015544A4 (en) Cell release method
EP3024081A4 (en) METHOD FOR PRODUCING CELLS
ZA201400415B (en) Method for operating an electrolytic cell
GB201301857D0 (en) Method
GB201309654D0 (en) Method
GB201305714D0 (en) Method
GB201301233D0 (en) Method
GB201300409D0 (en) Method
PL2978839T3 (pl) Sposób hodowli komórek
IL240033A0 (en) A method for assessing the aging of a cell
PT2821771T (pt) Método de teste
EP2817395A4 (en) PROCESS FOR THE PRODUCTION OF BIODIESEL
GB201310151D0 (en) Novel method