DK2941483T3 - Fremgangsmåde til at opnå immunstimulerende dendritriske celler - Google Patents
Fremgangsmåde til at opnå immunstimulerende dendritriske celler Download PDFInfo
- Publication number
- DK2941483T3 DK2941483T3 DK14700025.1T DK14700025T DK2941483T3 DK 2941483 T3 DK2941483 T3 DK 2941483T3 DK 14700025 T DK14700025 T DK 14700025T DK 2941483 T3 DK2941483 T3 DK 2941483T3
- Authority
- DK
- Denmark
- Prior art keywords
- immunstimulating
- procedure
- dendritric cells
- dendritric
- cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/428—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/115—Platelets, megakaryocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
- C12N2506/115—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells from monocytes, from macrophages
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2529/00—Culture process characterised by the use of electromagnetic stimulation
- C12N2529/10—Stimulation by light
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361748546P | 2013-01-03 | 2013-01-03 | |
| GBGB1300049.2A GB201300049D0 (en) | 2013-01-03 | 2013-01-03 | Method for obtaining immuno-stimulatory dendritic cells |
| PCT/EP2014/050010 WO2014106629A1 (en) | 2013-01-03 | 2014-01-02 | Method for obtaining immuno-stimulatory dendritic cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2941483T3 true DK2941483T3 (da) | 2020-06-02 |
Family
ID=47747911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14700025.1T DK2941483T3 (da) | 2013-01-03 | 2014-01-02 | Fremgangsmåde til at opnå immunstimulerende dendritriske celler |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20160298082A1 (da) |
| EP (2) | EP3741843B1 (da) |
| JP (1) | JP6621665B2 (da) |
| KR (3) | KR20150122638A (da) |
| CN (2) | CN105008522A (da) |
| AU (1) | AU2014204344B2 (da) |
| CA (2) | CA3187235A1 (da) |
| DK (1) | DK2941483T3 (da) |
| ES (2) | ES2987346T3 (da) |
| GB (1) | GB201300049D0 (da) |
| PL (2) | PL2941483T3 (da) |
| WO (1) | WO2014106629A1 (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2656156C2 (ru) | 2011-10-17 | 2018-05-31 | Массачусетс Инститьют Оф Текнолоджи | Внутриклеточная доставка |
| KR102304167B1 (ko) | 2013-08-16 | 2021-09-24 | 메사추세츠 인스티튜트 오브 테크놀로지 | 세포로의 선택적 물질 전달 |
| ES2796090T3 (es) * | 2014-02-10 | 2020-11-25 | Inst Curie | Uso de moduladores MCOLN-1 para regular la migración celular |
| GB201413665D0 (en) * | 2014-07-03 | 2014-09-17 | Transimmune Ag And Yale University | Method for obtaining globally activated monocytes |
| RU2739794C2 (ru) | 2014-10-31 | 2020-12-28 | Массачусетс Инститьют Оф Текнолоджи | Доставка биомолекул в клетки иммунной системы |
| US10526573B2 (en) | 2014-11-14 | 2020-01-07 | Massachusetts Institute Of Technology | Disruption and field enabled delivery of compounds and compositions into cells |
| US11125739B2 (en) | 2015-01-12 | 2021-09-21 | Massachusetts Institute Of Technology | Gene editing through microfluidic delivery |
| GB201513278D0 (en) * | 2015-07-03 | 2015-09-09 | Transimmune Ag And Yale University | Device and method for obtaining immunostimulatory antigen-presenting cells |
| JP6925984B2 (ja) | 2015-07-09 | 2021-08-25 | マサチューセッツ インスティテュート オブ テクノロジー | 無核細胞への物質の送達 |
| CN105039256A (zh) * | 2015-07-13 | 2015-11-11 | 中政道和（北京）生物科技有限公司 | 一种支气管镜下获取肿瘤组织进行树突细胞培养扩增方法 |
| WO2017037707A1 (en) | 2015-09-02 | 2017-03-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Antibodies specific to human t-cell immunoglobulin and itim domain (tigit) |
| EP3518942A4 (en) * | 2016-09-29 | 2020-05-27 | Hadasit Medical Research Services&Development Ltd. | DENDRITIC CELL PREPARATIONS, COMPOSITIONS AND METHODS OF USE |
| KR102356510B1 (ko) * | 2017-09-05 | 2022-02-08 | 메디진 이뮤노테라피스 게엠바하 | 수지상 세포 효능 분석 |
| GB201715445D0 (en) * | 2017-09-25 | 2017-11-08 | Senzagen Ab | Novel cell line and uses thereof |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| MX2021008022A (es) | 2019-01-07 | 2021-08-05 | Shattuck Labs Inc | Proteínas heterodiméricas para modular células t gamma delta. |
| US11098093B2 (en) | 2019-01-07 | 2021-08-24 | Shattuck Labs, Inc. | Heterodimeric proteins for modulating gamma delta T cells |
| CN112301057B (zh) * | 2019-07-30 | 2023-02-21 | 上海市第一人民医院 | 一种重组腺相关病毒载体及其制备方法与应用 |
| CN115135779A (zh) * | 2019-11-13 | 2022-09-30 | 科罗拉多大学董事会, 法人团体 | 鉴定宿主rna感染生物标志物 |
| WO2023006982A1 (en) | 2021-07-29 | 2023-02-02 | Transimmune Ag | Methods for selectively reducing immunogenicity in a transplant |
| KR20240040111A (ko) * | 2021-07-29 | 2024-03-27 | 트랜스이뮨 아게 | 선택적 관용화 - 관용성 수지상 세포를 선택적으로 생성하는 방법 |
| CN116381247A (zh) * | 2022-12-26 | 2023-07-04 | 上海生物芯片有限公司 | 一种同时检测il-6和il-8的试剂盒及方法 |
| EP4704883A1 (en) | 2023-05-01 | 2026-03-11 | Yale University | Antigen-specific physiologic dendritic cells for therapy |
| WO2024227807A1 (en) | 2023-05-01 | 2024-11-07 | Yale University | Antigen-specific physiologic dendritic cells for vaccination |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050158856A1 (en) * | 1999-04-20 | 2005-07-21 | Edelson Richard L. | Methods for producing functional antigen presenting dendritic cells using biodegradable microparticles for delivery of antigenic materials |
| EP1176986B1 (en) | 1999-04-20 | 2018-07-04 | Yale University | Differentiation of monocytes into functional dendritic cells |
| US7727523B2 (en) * | 2001-08-13 | 2010-06-01 | Yale University | Method for suppressing immune system response to transplanted tissue or cells |
| AU2003293411B2 (en) * | 2002-12-06 | 2010-10-28 | Northwest Biotherapeutics, Inc. | Administration of dendritic cells partially matured in vitro for the treatment of tumors |
| US8524495B2 (en) * | 2007-05-16 | 2013-09-03 | Yale University | Methods for inducing the differentiation of blood monocytes into functional dendritic cells |
| JP5819314B2 (ja) * | 2009-12-11 | 2015-11-24 | エータイアー ファーマ， インコーポレイテッド | 炎症を調節するためのアミノアシルｔＲＮＡシンテターゼ |
-
2013
- 2013-01-03 GB GBGB1300049.2A patent/GB201300049D0/en not_active Ceased
-
2014
- 2014-01-02 EP EP20160435.2A patent/EP3741843B1/en active Active
- 2014-01-02 PL PL14700025T patent/PL2941483T3/pl unknown
- 2014-01-02 EP EP14700025.1A patent/EP2941483B1/en active Active
- 2014-01-02 PL PL20160435.2T patent/PL3741843T3/pl unknown
- 2014-01-02 KR KR1020157020665A patent/KR20150122638A/ko not_active Ceased
- 2014-01-02 WO PCT/EP2014/050010 patent/WO2014106629A1/en not_active Ceased
- 2014-01-02 JP JP2015551178A patent/JP6621665B2/ja active Active
- 2014-01-02 KR KR1020187034193A patent/KR20180128993A/ko not_active Ceased
- 2014-01-02 KR KR1020207011396A patent/KR20200043549A/ko not_active Ceased
- 2014-01-02 ES ES20160435T patent/ES2987346T3/es active Active
- 2014-01-02 DK DK14700025.1T patent/DK2941483T3/da active
- 2014-01-02 AU AU2014204344A patent/AU2014204344B2/en active Active
- 2014-01-02 CN CN201480003950.8A patent/CN105008522A/zh active Pending
- 2014-01-02 CA CA3187235A patent/CA3187235A1/en active Pending
- 2014-01-02 CA CA2897109A patent/CA2897109C/en active Active
- 2014-01-02 CN CN201810815275.9A patent/CN109161528A/zh active Pending
- 2014-01-02 ES ES14700025T patent/ES2795926T3/es active Active
- 2014-01-02 US US14/759,012 patent/US20160298082A1/en not_active Abandoned
-
2021
- 2021-10-26 US US17/510,981 patent/US20220112462A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2014204344A1 (en) | 2015-07-02 |
| JP2016504912A (ja) | 2016-02-18 |
| EP2941483B1 (en) | 2020-03-04 |
| EP3741843C0 (en) | 2024-06-26 |
| CA3187235A1 (en) | 2014-07-10 |
| AU2014204344B2 (en) | 2017-04-06 |
| JP6621665B2 (ja) | 2019-12-18 |
| EP3741843B1 (en) | 2024-06-26 |
| EP2941483A1 (en) | 2015-11-11 |
| KR20200043549A (ko) | 2020-04-27 |
| US20160298082A1 (en) | 2016-10-13 |
| CA2897109C (en) | 2023-03-28 |
| EP3741843A1 (en) | 2020-11-25 |
| HK1210625A1 (en) | 2016-04-29 |
| US20220112462A1 (en) | 2022-04-14 |
| GB201300049D0 (en) | 2013-02-20 |
| WO2014106629A1 (en) | 2014-07-10 |
| CN105008522A (zh) | 2015-10-28 |
| KR20180128993A (ko) | 2018-12-04 |
| ES2795926T3 (es) | 2020-11-25 |
| CN109161528A (zh) | 2019-01-08 |
| PL3741843T3 (pl) | 2025-01-07 |
| KR20150122638A (ko) | 2015-11-02 |
| CA2897109A1 (en) | 2014-07-10 |
| ES2987346T3 (es) | 2024-11-14 |
| PL2941483T3 (pl) | 2020-09-21 |
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