HK1210184A1 - Affinity matured crig variants crig - Google Patents

Affinity matured crig variants crig

Info

Publication number
HK1210184A1
HK1210184A1 HK15110724.5A HK15110724A HK1210184A1 HK 1210184 A1 HK1210184 A1 HK 1210184A1 HK 15110724 A HK15110724 A HK 15110724A HK 1210184 A1 HK1210184 A1 HK 1210184A1
Authority
HK
Hong Kong
Prior art keywords
crig
variants
affinity matured
affinity
crig variants
Prior art date
Application number
HK15110724.5A
Other languages
English (en)
Chinese (zh)
Inventor
薩科德夫.
.西多
李冰
曼諾.范盧克倫坎帕格尼
克里斯琴.威斯曼
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41168511&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1210184(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of HK1210184A1 publication Critical patent/HK1210184A1/xx

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
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    • A61P11/06Antiasthmatics
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    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P31/14Antivirals for RNA viruses
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
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    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
HK15110724.5A 2008-05-06 2015-10-29 Affinity matured crig variants crig HK1210184A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5088808P 2008-05-06 2008-05-06
US18965308P 2008-08-20 2008-08-20

Publications (1)

Publication Number Publication Date
HK1210184A1 true HK1210184A1 (en) 2016-04-15

Family

ID=41168511

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15110724.5A HK1210184A1 (en) 2008-05-06 2015-10-29 Affinity matured crig variants crig

Country Status (28)

Country Link
US (2) US9234024B2 (ru)
EP (2) EP3141560A3 (ru)
JP (2) JP5836800B2 (ru)
KR (2) KR101690590B1 (ru)
CN (2) CN104558151A (ru)
AR (1) AR071635A1 (ru)
AU (1) AU2009244300B2 (ru)
BR (1) BRPI0912003A2 (ru)
CA (1) CA2720685C (ru)
CL (1) CL2009001083A1 (ru)
CY (1) CY1118240T1 (ru)
DK (1) DK2280996T3 (ru)
ES (1) ES2605471T3 (ru)
HK (1) HK1210184A1 (ru)
HR (1) HRP20161580T1 (ru)
HU (1) HUE030092T2 (ru)
IL (2) IL208379A (ru)
LT (1) LT2280996T (ru)
MX (1) MX2010011372A (ru)
PE (2) PE20141549A1 (ru)
PL (1) PL2280996T3 (ru)
PT (1) PT2280996T (ru)
RU (2) RU2553517C2 (ru)
SG (1) SG190596A1 (ru)
SI (1) SI2280996T1 (ru)
TW (1) TWI508973B (ru)
WO (1) WO2009137605A2 (ru)
ZA (1) ZA201006937B (ru)

Families Citing this family (5)

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CN104231085B (zh) 2013-09-05 2017-03-15 复旦大学附属肿瘤医院 靶向特异性补体系统抑制剂、其制备方法及应用
WO2021110127A1 (en) * 2019-12-06 2021-06-10 Cheer Global Limited Method of treating inflammatory bowel disease
CN113583107B (zh) * 2021-07-28 2023-11-10 复旦大学 CRIg功能区蛋白变体及其应用
WO2023080788A1 (en) * 2021-11-05 2023-05-11 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Tryptophan depletion induces production and presentation of tryptophan to phenylalanine substitutions
US20240132617A1 (en) * 2022-09-20 2024-04-25 Visterra, Inc. Treatment of complement mediated diseases and disorders with c3b antibodies

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Publication number Publication date
SI2280996T1 (sl) 2016-12-30
ES2605471T3 (es) 2017-03-14
BRPI0912003A2 (pt) 2016-07-12
LT2280996T (lt) 2016-12-12
IL208379A (en) 2016-12-29
US9234024B2 (en) 2016-01-12
EP2280996A2 (en) 2011-02-09
CA2720685A1 (en) 2009-11-12
WO2009137605A2 (en) 2009-11-12
WO2009137605A3 (en) 2010-01-21
CL2009001083A1 (es) 2011-01-07
RU2553517C2 (ru) 2015-06-20
CA2720685C (en) 2017-04-18
IL208379A0 (en) 2010-12-30
AU2009244300A1 (en) 2009-11-12
CN104558151A (zh) 2015-04-29
HUE030092T2 (en) 2017-05-29
JP2011519950A (ja) 2011-07-14
PT2280996T (pt) 2016-12-06
RU2015117054A (ru) 2015-10-20
AU2009244300B2 (en) 2014-04-17
KR20170001711A (ko) 2017-01-04
AU2009244300A2 (en) 2011-04-14
JP2015145369A (ja) 2015-08-13
KR101690590B1 (ko) 2016-12-28
CN102015763B (zh) 2014-12-24
KR20110020798A (ko) 2011-03-03
EP3141560A3 (en) 2017-05-24
IL249492A0 (en) 2017-02-28
MX2010011372A (es) 2010-11-12
HRP20161580T1 (hr) 2016-12-30
DK2280996T3 (en) 2016-12-19
AR071635A1 (es) 2010-06-30
US20160008427A1 (en) 2016-01-14
EP2280996B1 (en) 2016-09-07
PE20091923A1 (es) 2009-12-19
US20100150908A1 (en) 2010-06-17
PL2280996T3 (pl) 2017-07-31
CN102015763A (zh) 2011-04-13
TW200948377A (en) 2009-12-01
CY1118240T1 (el) 2017-06-28
RU2010149804A (ru) 2012-06-20
SG190596A1 (en) 2013-06-28
ZA201006937B (en) 2012-01-25
PE20141549A1 (es) 2014-10-25
JP5836800B2 (ja) 2015-12-24
TWI508973B (zh) 2015-11-21
EP3141560A2 (en) 2017-03-15

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