HK1210154A1 - Highly selective c-met inhibitors as anticancer agents c-met - Google Patents
Highly selective c-met inhibitors as anticancer agents c-metInfo
- Publication number
- HK1210154A1 HK1210154A1 HK15110897.6A HK15110897A HK1210154A1 HK 1210154 A1 HK1210154 A1 HK 1210154A1 HK 15110897 A HK15110897 A HK 15110897A HK 1210154 A1 HK1210154 A1 HK 1210154A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- met
- anticancer agents
- highly selective
- inhibitors
- met inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2012103223591A CN103122000B (zh) | 2012-09-03 | 2012-09-03 | 用作抗肿瘤药物的高选择性的c-Met激酶抑制剂 |
PCT/CN2013/080598 WO2014032498A1 (en) | 2012-09-03 | 2013-08-01 | Highly selective c-met inhibitors as anticancer agents |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1210154A1 true HK1210154A1 (en) | 2016-04-15 |
Family
ID=48453178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15110897.6A HK1210154A1 (en) | 2012-09-03 | 2015-11-04 | Highly selective c-met inhibitors as anticancer agents c-met |
Country Status (6)
Country | Link |
---|---|
US (1) | US9695175B2 (ja) |
EP (1) | EP2892904B1 (ja) |
JP (1) | JP6106899B2 (ja) |
CN (1) | CN103122000B (ja) |
HK (1) | HK1210154A1 (ja) |
WO (1) | WO2014032498A1 (ja) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105326793A (zh) * | 2014-08-06 | 2016-02-17 | 中美冠科生物技术(太仓)有限公司 | 一种包含c-Met激酶抑制剂的固体分散体及其制备方法和用途 |
CN108853108A (zh) | 2015-12-31 | 2018-11-23 | 北京浦润奥生物科技有限责任公司 | 化合物在制备用于治疗脑胶质瘤的药物中的用途 |
CN109206357A (zh) * | 2017-07-04 | 2019-01-15 | 浙江九洲药业股份有限公司 | 一种格列齐特中间体的通式化合物及其制备方法和应用 |
EP3752528A4 (en) * | 2018-02-17 | 2021-11-03 | Apollomics Inc. | CANCER TREATMENT USING A COMBINATION OF A NEUTROPHIL MODULATOR WITH AN IMMUNE CHECKPOINT MODULATOR |
AU2019395282A1 (en) * | 2018-12-14 | 2021-07-08 | Beta Pharma, Inc. | Organophosphorus-substituted compounds as c-MET inhibitors and therapeutic uses thereof |
EP3942045A1 (en) | 2019-03-21 | 2022-01-26 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
CN114599978A (zh) * | 2019-06-06 | 2022-06-07 | 浙江冠科美博生物科技有限公司 | 使用c-met抑制剂治疗癌症患者的方法 |
EP4054579A1 (en) | 2019-11-08 | 2022-09-14 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
US20230338294A1 (en) * | 2020-04-26 | 2023-10-26 | Apollomics Inc. | Novel pharmaceutical formulation for c-met inhibitor |
CN113105436B (zh) * | 2021-04-20 | 2022-07-01 | 西格莱(苏州)生物医药有限公司 | 吡唑类化合物的制备方法及其中间体 |
WO2024068947A1 (en) | 2022-09-30 | 2024-04-04 | Syngenta Crop Protection Ag | Microbiocidal pyrazole derivatives |
WO2024068950A1 (en) | 2022-09-30 | 2024-04-04 | Syngenta Crop Protection Ag | Microbiocidal pyrazole derivatives |
CN116854694A (zh) * | 2023-07-04 | 2023-10-10 | 北京浦润奥生物科技有限责任公司 | [1,2,4]三唑[4,3-b]哒嗪化合物的晶型及其制备方法和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8030305B2 (en) | 2005-12-21 | 2011-10-04 | Janssen Pharmaceutica N.V. | Triazolopyridazines as kinase modulators |
PE20121506A1 (es) * | 2006-07-14 | 2012-11-26 | Amgen Inc | Compuestos triazolopiridinas como inhibidores de c-met |
JP2010507577A (ja) * | 2006-10-23 | 2010-03-11 | エスジーエックス ファーマシューティカルズ、インコーポレイテッド | トリアゾロピリダジンタンパク質キナーゼモジュレーター |
CN101558070A (zh) * | 2006-10-23 | 2009-10-14 | Sgx药品公司 | 三唑并哒嗪蛋白激酶调节剂 |
AU2007309149C1 (en) * | 2006-10-23 | 2013-04-04 | Sgx Pharmaceuticals, Inc. | Bicyclic triazoles as protein kinase modulators |
BRPI0908504A2 (pt) * | 2008-02-28 | 2015-08-11 | Novatis Ag | Compostos derivados de 3-metil-imidazo[1,2-b]piridazina, uso dos mesmos e composição farmacêutica |
AR085183A1 (es) * | 2010-07-30 | 2013-09-18 | Lilly Co Eli | Compuesto 6-(1-metil-1h-pirazol-4-il)-3-(2-metil-2h-indazol-5-iltio)-[1,2,4]triazol[4,3-b]piridazina, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para tratar cancer |
-
2012
- 2012-09-03 CN CN2012103223591A patent/CN103122000B/zh active Active
-
2013
- 2013-08-01 EP EP13832587.3A patent/EP2892904B1/en active Active
- 2013-08-01 US US14/424,395 patent/US9695175B2/en active Active
- 2013-08-01 JP JP2015528851A patent/JP6106899B2/ja active Active
- 2013-08-01 WO PCT/CN2013/080598 patent/WO2014032498A1/en active Application Filing
-
2015
- 2015-11-04 HK HK15110897.6A patent/HK1210154A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO2014032498A1 (en) | 2014-03-06 |
JP6106899B2 (ja) | 2017-04-05 |
US20150218171A1 (en) | 2015-08-06 |
CN103122000A (zh) | 2013-05-29 |
US9695175B2 (en) | 2017-07-04 |
JP2015526486A (ja) | 2015-09-10 |
EP2892904A4 (en) | 2016-04-06 |
EP2892904B1 (en) | 2018-10-17 |
CN103122000B (zh) | 2013-12-25 |
EP2892904A1 (en) | 2015-07-15 |
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