HK1207881A1 - 改進的酶變體 - Google Patents

改進的酶變體

Info

Publication number
HK1207881A1
HK1207881A1 HK15108396.6A HK15108396A HK1207881A1 HK 1207881 A1 HK1207881 A1 HK 1207881A1 HK 15108396 A HK15108396 A HK 15108396A HK 1207881 A1 HK1207881 A1 HK 1207881A1
Authority
HK
Hong Kong
Prior art keywords
enzyme variants
improved enzyme
improved
variants
enzyme
Prior art date
Application number
HK15108396.6A
Other languages
English (en)
Inventor
彼得勒斯．雅各布斯．特奧多魯斯．德克
雷奈．馬塞爾．容．德
邁克爾．丹尼斯．坦貝玲
科內利斯．馬里納斯．穆伊爾維克
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of HK1207881A1 publication Critical patent/HK1207881A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/02—Making cheese curd
    • A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/02—Making cheese curd
    • A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
    • A23C19/0326—Rennet produced by fermentation, e.g. microbial rennet; Rennet produced by genetic engineering
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/06—Treating cheese curd after whey separation; Products obtained thereby
    • A23C19/068—Particular types of cheese
    • A23C19/0684—Soft uncured Italian cheeses, e.g. Mozarella, Ricotta, Pasta filata cheese; Other similar stretched cheeses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/06—Treating cheese curd after whey separation; Products obtained thereby
    • A23C19/068—Particular types of cheese
    • A23C19/072—Cheddar type or similar hard cheeses without eyes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6483—Chymosin (3.4.23.4), i.e. rennin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23—Aspartic endopeptidases (3.4.23)
    • C12Y304/23004—Chymosin (3.4.23.4), i.e. rennin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C2220/00—Biochemical treatment
    • A23C2220/20—Treatment with microorganisms
    • A23C2220/202—Genetic engineering of microorganisms used in dairy technology
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C2250/00—Particular aspects related to cheese
    • A23C2250/15—Shredded non-dried cheese

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dairy Products (AREA)
HK15108396.6A 2012-05-03 2015-08-28 改進的酶變體 HK1207881A1 (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261642095P 2012-05-03 2012-05-03
EP12166673 2012-05-03
US201261745063P 2012-12-21 2012-12-21
EP12199178 2012-12-21
EP12199277 2012-12-21
PCT/EP2013/059317 WO2013164481A1 (en) 2012-05-03 2013-05-03 Improved enzyme variants

Publications (1)

Publication Number Publication Date
HK1207881A1 true HK1207881A1 (zh) 2016-02-12

Family

ID=49514227

Family Applications (2)

Application Number Title Priority Date Filing Date
HK15108395.7A HK1207880A1 (zh) 2012-05-03 2015-08-28 改進的酶變體
HK15108396.6A HK1207881A1 (zh) 2012-05-03 2015-08-28 改進的酶變體

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK15108395.7A HK1207880A1 (zh) 2012-05-03 2015-08-28 改進的酶變體

Country Status (12)

Country Link
US (3) US9822352B2 (zh)
EP (3) EP2844751B1 (zh)
AU (2) AU2013255747A1 (zh)
BR (2) BR112014027371A2 (zh)
CA (2) CA2872132C (zh)
DK (2) DK2844751T3 (zh)
EA (2) EA035275B1 (zh)
HK (2) HK1207880A1 (zh)
LT (2) LT2844751T (zh)
MX (2) MX357563B (zh)
NZ (1) NZ701125A (zh)
WO (2) WO2013164481A1 (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3929288A1 (en) * 2012-05-25 2021-12-29 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
KR102494645B1 (ko) 2014-02-26 2023-02-06 시에이치알. 한센 에이/에스 개선된 응유 특성을 갖는 키모신 변이체
WO2016128476A1 (en) 2015-02-10 2016-08-18 Chr. Hansen A/S Blends of chymosins with improved milk-clotting properties
DK3310914T3 (da) 2015-06-22 2022-06-20 Chr Hansen As Chymosinvarianter med forbedrede egenskaber
CA2995755A1 (en) * 2015-08-31 2017-03-09 Chr. Hansen A/S Variants of chymosin with improved properties
EP3143879A1 (en) 2015-09-18 2017-03-22 DSM IP Assets B.V. Yogurt with reduced ripening
GB201517601D0 (en) * 2015-10-06 2015-11-18 Dale Farm Ltd Improvements relating to cheese making
US10961524B2 (en) * 2016-05-19 2021-03-30 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
WO2017198810A1 (en) * 2016-05-19 2017-11-23 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
CN106754840B (zh) * 2016-12-22 2019-06-21 江南大学 一种酶活及热稳定性改善的凝乳酶突变体
WO2019137983A1 (en) * 2018-01-11 2019-07-18 Chr. Hansen A/S Interactions between cultures, coagulants and technology to increase cheese yields
CN109182311B (zh) * 2018-10-11 2021-07-27 山东隆科特酶制剂有限公司 一种用于沂蒙黑山羊乳奶酪的凝乳酶
WO2023001832A1 (en) 2021-07-20 2023-01-26 Chr. Hansen A/S Composition for clotting milk, methods and uses thereof
AU2023249315A1 (en) 2022-04-06 2024-09-26 Chr. Hansen A/S Aspartic protease, methods and uses thereof
WO2024189187A1 (en) 2023-03-15 2024-09-19 Dsm Ip Assets B.V. Novel process for producing a fermented milk product and new fermented milk product so produced

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2365069T3 (en) * 2000-11-06 2018-04-23 Eidgenoessisch Technische Hochschule Zuerich Process for the preparation of non-bovine chymosin and its use
WO2008008766A2 (en) * 2006-07-10 2008-01-17 Ohio University Co-expression of proline hydroxylases to facilitate hyp-glycosylation of proteins expressed and secreted in plant cells
WO2008098973A1 (en) 2007-02-13 2008-08-21 Chr. Hansen A/S Coagulation of milk

Also Published As

Publication number Publication date
AU2013255747A1 (en) 2014-11-06
CA2872132C (en) 2020-06-16
EP3450552A2 (en) 2019-03-06
LT2844750T (lt) 2018-09-10
HK1207880A1 (zh) 2016-02-12
CA2872309A1 (en) 2013-11-07
US9822352B2 (en) 2017-11-21
DK2844750T3 (en) 2018-10-01
EP3450552A3 (en) 2019-05-08
WO2013164481A1 (en) 2013-11-07
CA2872132A1 (en) 2013-11-07
EP2844750B1 (en) 2018-06-20
EA201401211A1 (ru) 2015-05-29
DK2844751T3 (en) 2019-02-04
BR112014027283A2 (pt) 2017-08-08
BR112014027371A2 (pt) 2017-08-08
CA2872309C (en) 2021-03-02
US20150140169A1 (en) 2015-05-21
EA201401209A1 (ru) 2015-05-29
US20180030427A1 (en) 2018-02-01
EP2844751A2 (en) 2015-03-11
NZ701125A (en) 2016-11-25
LT2844751T (lt) 2019-02-11
WO2013164479A3 (en) 2013-12-19
EA035275B1 (ru) 2020-05-22
MX355170B (es) 2018-04-05
US20150118356A1 (en) 2015-04-30
EA038324B1 (ru) 2021-08-10
US10253305B2 (en) 2019-04-09
AU2013255749A1 (en) 2014-11-06
MX2014013333A (es) 2015-02-10
WO2013164479A2 (en) 2013-11-07
EP2844750A1 (en) 2015-03-11
MX2014013329A (es) 2015-02-10
EP2844751B1 (en) 2018-10-17
US10167463B2 (en) 2019-01-01
MX357563B (es) 2018-07-13

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