HK1207371A1 - Pyrazolopyridine derivatives as ttx-s blockers ttx-s - Google Patents
Pyrazolopyridine derivatives as ttx-s blockers ttx-sInfo
- Publication number
- HK1207371A1 HK1207371A1 HK15107981.9A HK15107981A HK1207371A1 HK 1207371 A1 HK1207371 A1 HK 1207371A1 HK 15107981 A HK15107981 A HK 15107981A HK 1207371 A1 HK1207371 A1 HK 1207371A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- ttx
- blockers
- pyrazolopyridine derivatives
- pyrazolopyridine
- derivatives
- Prior art date
Links
- 150000005229 pyrazolopyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261720974P | 2012-10-31 | 2012-10-31 | |
| PCT/JP2013/006475 WO2014068988A1 (en) | 2012-10-31 | 2013-10-31 | Pyrazolopyridine derivatives as ttx-s blockers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1207371A1 true HK1207371A1 (en) | 2016-01-29 |
Family
ID=50626934
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15107981.9A HK1207371A1 (en) | 2012-10-31 | 2015-08-18 | Pyrazolopyridine derivatives as ttx-s blockers ttx-s |
| HK16100659.4A HK1212697A1 (zh) | 2012-10-31 | 2016-01-21 | 作為 阻斷劑的吡唑並吡啶衍生物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16100659.4A HK1212697A1 (zh) | 2012-10-31 | 2016-01-21 | 作為 阻斷劑的吡唑並吡啶衍生物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9944634B2 (xx) |
| EP (1) | EP2914597B1 (xx) |
| JP (1) | JP6225356B2 (xx) |
| KR (1) | KR102090945B1 (xx) |
| CN (1) | CN104812755B (xx) |
| BR (1) | BR112015009738A8 (xx) |
| CA (1) | CA2887887C (xx) |
| ES (1) | ES2661585T3 (xx) |
| HK (2) | HK1207371A1 (xx) |
| MX (1) | MX362417B (xx) |
| RU (1) | RU2652117C2 (xx) |
| TW (1) | TWI601726B (xx) |
| WO (1) | WO2014068988A1 (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI652014B (zh) * | 2013-09-13 | 2019-03-01 | 美商艾佛艾姆希公司 | 雜環取代之雙環唑殺蟲劑 |
| BR112019004085B1 (pt) | 2016-09-01 | 2022-10-04 | Nihon Nohyaku Co., Ltd. | Composto, composição inseticida agrícola e hortícola,método para usar um inseticida agrícola e hortícola, uso do composto ou do sal deste e composição para controle de ectoparasitas |
| US11154544B2 (en) | 2017-06-20 | 2021-10-26 | Raqualia Pharma Inc. | Amide derivatives as Nav1.7 and Nav1.8 blockers |
| EP3936192A4 (en) | 2019-03-06 | 2022-11-16 | Daiichi Sankyo Company, Limited | PYRROLOPYRAZOL DERIVATIVES |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ545717A (en) * | 2003-08-05 | 2009-12-24 | Vertex Pharma | Hydrogenated quinazoline derivatives as inhibitors of voltage-gated ion channels |
| JP4657384B2 (ja) * | 2007-05-03 | 2011-03-23 | ファイザー・リミテッド | ナトリウムチャンネルモジュレーターとしての２−ピリジンカルボキサミド誘導体 |
| MX2009014203A (es) * | 2007-06-26 | 2010-01-28 | Sanofi Aventis | Una sintesis de 2h-indazoles catalizada por un metal de transicion. |
| US8450343B2 (en) * | 2007-12-06 | 2013-05-28 | Xianhai Huang | Gamma secretase modulators |
| TWI436986B (zh) * | 2008-12-26 | 2014-05-11 | Dainippon Sumitomo Pharma Co | 新穎之２環性雜環化合物 |
| JP5732036B2 (ja) * | 2009-03-19 | 2015-06-10 | メディカル リサーチ カウンシル テクノロジーＭｅｄｉｃａｌ Ｒｅｓｅａｒｃｈ Ｃｏｕｎｃｉｌ Ｔｅｃｈｎｏｌｏｇｙ | 化合物 |
| WO2011153588A1 (en) * | 2010-06-10 | 2011-12-15 | Biota Scientific Management Pty Ltd | Viral polymerase inhibitors |
| JP2013530180A (ja) * | 2010-06-16 | 2013-07-25 | パーデュー、ファーマ、リミテッド、パートナーシップ | アリール置換インドールおよびその使用 |
| CN106478497B (zh) * | 2010-10-18 | 2020-05-08 | 拉夸里亚创药株式会社 | 作为ttx-s阻滞剂的芳胺衍生物 |
| BR112013011520A2 (pt) * | 2010-11-19 | 2019-09-24 | Hoffmann La Roche | pirazolo piridinas e pirazolo piridinas e seu uso como inibidores de tyk2 |
-
2013
- 2013-10-31 JP JP2015519668A patent/JP6225356B2/ja active Active
- 2013-10-31 BR BR112015009738A patent/BR112015009738A8/pt active IP Right Grant
- 2013-10-31 WO PCT/JP2013/006475 patent/WO2014068988A1/en active Application Filing
- 2013-10-31 MX MX2015005361A patent/MX362417B/es active IP Right Grant
- 2013-10-31 EP EP13851886.5A patent/EP2914597B1/en not_active Not-in-force
- 2013-10-31 TW TW102139712A patent/TWI601726B/zh active
- 2013-10-31 CN CN201380055016.6A patent/CN104812755B/zh not_active Expired - Fee Related
- 2013-10-31 US US14/434,203 patent/US9944634B2/en active Active
- 2013-10-31 CA CA2887887A patent/CA2887887C/en active Active
- 2013-10-31 RU RU2015120625A patent/RU2652117C2/ru active
- 2013-10-31 ES ES13851886.5T patent/ES2661585T3/es active Active
- 2013-10-31 KR KR1020157013574A patent/KR102090945B1/ko active IP Right Grant
-
2015
- 2015-08-18 HK HK15107981.9A patent/HK1207371A1/xx unknown
-
2016
- 2016-01-21 HK HK16100659.4A patent/HK1212697A1/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2887887C (en) | 2020-08-25 |
| EP2914597A1 (en) | 2015-09-09 |
| CA2887887A1 (en) | 2014-05-08 |
| WO2014068988A1 (en) | 2014-05-08 |
| EP2914597A4 (en) | 2016-04-20 |
| CN104812755B (zh) | 2017-08-08 |
| TWI601726B (zh) | 2017-10-11 |
| CN104812755A (zh) | 2015-07-29 |
| HK1212697A1 (zh) | 2016-06-17 |
| KR102090945B1 (ko) | 2020-05-27 |
| JP6225356B2 (ja) | 2017-11-08 |
| JP2015534941A (ja) | 2015-12-07 |
| KR20150074157A (ko) | 2015-07-01 |
| EP2914597B1 (en) | 2017-12-06 |
| MX2015005361A (es) | 2015-09-23 |
| US9944634B2 (en) | 2018-04-17 |
| RU2015120625A (ru) | 2016-12-20 |
| MX362417B (es) | 2019-01-16 |
| TW201427980A (zh) | 2014-07-16 |
| US20150291582A1 (en) | 2015-10-15 |
| BR112015009738A2 (pt) | 2017-07-11 |
| BR112015009738A8 (pt) | 2019-09-17 |
| ES2661585T3 (es) | 2018-04-02 |
| RU2652117C2 (ru) | 2018-04-25 |
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