HK1206736A1 - 抑制劑及其製備和使用方法 - Google Patents
抑制劑及其製備和使用方法Info
- Publication number
- HK1206736A1 HK1206736A1 HK15107305.8A HK15107305A HK1206736A1 HK 1206736 A1 HK1206736 A1 HK 1206736A1 HK 15107305 A HK15107305 A HK 15107305A HK 1206736 A1 HK1206736 A1 HK 1206736A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- seca
- making
- methods
- inhibitors
- seca inhibitors
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
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- A61P31/12—Antivirals
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- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/61—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
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- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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US201261656793P | 2012-06-07 | 2012-06-07 | |
US201361824857P | 2013-05-17 | 2013-05-17 | |
US201361826345P | 2013-05-22 | 2013-05-22 | |
PCT/US2013/044243 WO2013184755A2 (en) | 2012-06-07 | 2013-06-05 | Seca inhibitors and methods of making and using thereof |
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HK1206736A1 true HK1206736A1 (zh) | 2016-01-15 |
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EP (2) | EP2861580B1 (zh) |
CN (2) | CN110664816A (zh) |
AU (2) | AU2013271731A1 (zh) |
CA (2) | CA2875964C (zh) |
HK (1) | HK1206736A1 (zh) |
WO (1) | WO2013184755A2 (zh) |
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EP3071205B1 (en) | 2013-11-18 | 2020-02-05 | Forma Therapeutics, Inc. | Benzopiperazine compositions as bet bromodomain inhibitors |
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CN104876881A (zh) * | 2015-06-10 | 2015-09-02 | 河北大学 | 一种硫脲嘧啶衍生物及其制备方法和应用 |
CN107924131B (zh) | 2015-08-31 | 2020-12-25 | 三菱瓦斯化学株式会社 | 光刻用下层膜形成材料及其组合物用于形成光刻用下层膜的用途、以及抗蚀图案形成方法 |
US11143962B2 (en) | 2015-08-31 | 2021-10-12 | Mitsubishi Gas Chemical Company, Inc. | Material for forming underlayer film for lithography, composition for forming underlayer film for lithography, underlayer film for lithography and production method thereof, pattern forming method, resin, and purification method |
JP6848869B2 (ja) | 2015-09-10 | 2021-03-24 | 三菱瓦斯化学株式会社 | 化合物、樹脂、レジスト組成物又は感放射線性組成物、レジストパターン形成方法、アモルファス膜の製造方法、リソグラフィー用下層膜形成材料、リソグラフィー用下層膜形成用組成物、回路パターンの形成方法、及び、精製方法 |
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PE20181487A1 (es) | 2015-12-16 | 2018-09-18 | Bristol Myers Squibb Co | Heteroarilhidroxipirimidinonas como agonistas del receptor de apelina (apj) |
EP3452466B1 (en) | 2016-05-03 | 2020-08-12 | Amgen Inc. | Heterocyclic triazole compounds as agonists of the apj receptor |
EP3464278B1 (en) | 2016-05-26 | 2021-06-16 | F. Hoffmann-La Roche AG | Xanthone derivatives for the treatment and prophylaxis of hepatitis b virus disease |
EP3484528B1 (en) | 2016-07-18 | 2020-11-25 | Janssen Pharmaceutica NV | Tau pet imaging ligands |
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WO2018097944A1 (en) | 2016-11-16 | 2018-05-31 | Amgen Inc. | Triazole furan compounds as agonists of the apj receptor |
WO2018093576A1 (en) | 2016-11-16 | 2018-05-24 | Amgen Inc. | Alkyl substituted triazole compounds as agonists of the apj receptor |
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WO2018093580A1 (en) | 2016-11-16 | 2018-05-24 | Amgen Inc. | Triazole pyridyl compounds as agonists of the apj receptor |
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WO2018097215A1 (ja) * | 2016-11-24 | 2018-05-31 | 三菱瓦斯化学株式会社 | 化合物、樹脂、組成物、パターン形成方法及び精製方法 |
US20190367457A1 (en) | 2016-12-30 | 2019-12-05 | Mitobridge, Inc. | Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (acmsd) inhibitors |
EP3704122B1 (en) | 2017-11-03 | 2021-09-01 | Amgen Inc. | Fused triazole agonists of the apj receptor |
EP3788037A1 (en) | 2018-05-01 | 2021-03-10 | Amgen Inc. | Substituted pyrimidinones as agonists of the apj receptor |
AU2019324089B2 (en) | 2018-08-21 | 2024-06-13 | Kyorin Pharmaceutical Co., Ltd. | Bicyclic heteroaromatic ring derivative |
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JP7549345B2 (ja) * | 2019-02-08 | 2024-09-11 | 学校法人近畿大学 | 悪性腫瘍疾患の改善用組成物 |
KR20220028075A (ko) | 2019-07-03 | 2022-03-08 | 스미토모 다이니폰 파마 온콜로지, 인크. | 티로신 키나제 비-수용체 1 (tnk1) 억제제 및 그의 용도 |
CN113896620B (zh) | 2020-10-26 | 2022-11-15 | 江西施美药业股份有限公司 | 补骨脂酚衍生物、其药学上可接受的盐及其制备方法和应用 |
CN113185511B (zh) * | 2021-05-24 | 2022-04-26 | 中国医学科学院医药生物技术研究所 | 一种嘧啶类化合物及其制备方法和应用 |
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WO2008098143A2 (en) * | 2007-02-08 | 2008-08-14 | Trius Therapeutics | Antimicrobial compounds and methods of use |
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- 2013-06-05 CN CN201910934072.6A patent/CN110664816A/zh active Pending
- 2013-06-05 EP EP13730985.2A patent/EP2861580B1/en not_active Not-in-force
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- 2013-06-05 EP EP18168338.4A patent/EP3409666A3/en not_active Withdrawn
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2015
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2017
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2018
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EP3409666A3 (en) | 2019-01-02 |
CN110664816A (zh) | 2020-01-10 |
WO2013184755A3 (en) | 2015-07-16 |
WO2013184755A2 (en) | 2013-12-12 |
CA2875964C (en) | 2018-01-02 |
CA2875964A1 (en) | 2013-12-12 |
US9957247B2 (en) | 2018-05-01 |
EP3409666A2 (en) | 2018-12-05 |
US20150152077A1 (en) | 2015-06-04 |
CA2985787A1 (en) | 2013-12-12 |
EP2861580B1 (en) | 2018-04-25 |
CN104870438A (zh) | 2015-08-26 |
US20180222880A1 (en) | 2018-08-09 |
AU2017213475A1 (en) | 2017-08-31 |
AU2013271731A1 (en) | 2014-12-18 |
AU2017213475B2 (en) | 2019-06-06 |
EP2861580A2 (en) | 2015-04-22 |
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