HK1206249A1 - 人自分泌運動因子 的抗體及其使用方法 - Google Patents

人自分泌運動因子 的抗體及其使用方法

Info

Publication number
HK1206249A1
HK1206249A1 HK15106808.2A HK15106808A HK1206249A1 HK 1206249 A1 HK1206249 A1 HK 1206249A1 HK 15106808 A HK15106808 A HK 15106808A HK 1206249 A1 HK1206249 A1 HK 1206249A1
Authority
HK
Hong Kong
Prior art keywords
autotaxin
methods
antibodies
human
human autotaxin
Prior art date
Application number
HK15106808.2A
Other languages
English (en)
Inventor
Sheri Moores
Jose Pardinas
Barry L Ziober
Ellen Chi
Thai Dinh
Suzanne Edavettal
Sandra Fenton
Damon Hamel
H Mimi Zhou
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of HK1206249A1 publication Critical patent/HK1206249A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK15106808.2A 2012-03-15 2015-07-17 人自分泌運動因子 的抗體及其使用方法 HK1206249A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261611241P 2012-03-15 2012-03-15
PCT/US2013/030235 WO2013138241A1 (en) 2012-03-15 2013-03-11 Human autotaxin antibodies and methods of use

Publications (1)

Publication Number Publication Date
HK1206249A1 true HK1206249A1 (zh) 2016-01-08

Family

ID=49161692

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15106808.2A HK1206249A1 (zh) 2012-03-15 2015-07-17 人自分泌運動因子 的抗體及其使用方法

Country Status (4)

Country Link
US (1) US20150087812A1 (zh)
EP (1) EP2825199A4 (zh)
HK (1) HK1206249A1 (zh)
WO (1) WO2013138241A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2015147290A1 (ja) * 2014-03-27 2017-04-13 株式会社リボミック オートタキシンに結合しオートタキシンの生理活性を阻害するアプタマー及びその利用
FR3020063A1 (fr) * 2014-04-16 2015-10-23 Gamamabs Pharma Anticorps humain anti-her4
JP6586669B2 (ja) * 2014-04-24 2019-10-09 株式会社リボミック オートタキシンに結合しオートタキシンの生理活性を阻害するアプタマー及びその利用
BR112018012344A2 (pt) * 2015-12-17 2018-12-04 Janssen Biotech Inc anticorpos que se ligam especificamente a hla-dr e seus usos
WO2019023056A1 (en) * 2017-07-24 2019-01-31 Janssen Biotech, Inc. INSULIN RECEPTOR ANTIBODIES AND USES THEREOF
US11266690B2 (en) * 2018-02-01 2022-03-08 Nanjing Iaso Biotherapeutics Co., Ltd. Chimeric antigen receptor (CAR) binding to BCMA, and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030153730A1 (en) * 1992-01-17 2003-08-14 Mary Stracke Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy
US5731167A (en) * 1992-01-17 1998-03-24 The United States Of America As Represented By The Department Of Health And Human Services Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy
JP2002543789A (ja) * 1999-05-07 2002-12-24 ザイモジェネティクス，インコーポレイティド オートタキシン変異体および代謝性疾患を治療するための使用
EP1343820A4 (en) * 2000-10-13 2005-09-14 Uab Research Foundation ANTI-EPIDERMIC GROWTH FACTOR RECEPTOR SINGLE CHAIN ANTIBODY
US7166716B2 (en) * 2002-06-06 2007-01-23 The Burnham Institute ATM related kinase ATX, nucleic acids encoding same and methods of use
CN101523213B (zh) * 2006-08-03 2017-03-08 国立大学法人东京大学 天然形式人自分泌运动因子特异的抗体、其筛选方法、以及通过测定自分泌运动因子而检测恶性淋巴瘤的方法和检测试剂
JP2011507519A (ja) * 2007-12-19 2011-03-10 セントコア・オーソ・バイオテツク・インコーポレーテツド ｐＩＸ又はｐＶＩＩへの融合を介したヒトデノボｐＩＸファージディスプレイライブラリの設計及び作製、ベクター、抗体、及び方法
EP2324852B1 (en) * 2008-08-07 2015-07-08 Nagasaki University Therapeutic or prophylactic agent for generalized pain syndrome
JP5560608B2 (ja) * 2009-08-18 2014-07-30 東ソー株式会社 オートタキシンの精製方法
WO2011151461A2 (en) * 2010-06-04 2011-12-08 B.S.R.C. "Alexander Fleming" Autotaxin pathway modulation and uses thereof

Also Published As

Publication number Publication date
US20150087812A1 (en) 2015-03-26
WO2013138241A1 (en) 2013-09-19
EP2825199A1 (en) 2015-01-21
EP2825199A4 (en) 2016-01-27

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