HK1204574A1 - 多價腦膜炎球菌衍生的多糖-蛋白質綴合物及疫苗 - Google Patents

多價腦膜炎球菌衍生的多糖-蛋白質綴合物及疫苗

Info

Publication number
HK1204574A1
HK1204574A1 HK15105208.0A HK15105208A HK1204574A1 HK 1204574 A1 HK1204574 A1 HK 1204574A1 HK 15105208 A HK15105208 A HK 15105208A HK 1204574 A1 HK1204574 A1 HK 1204574A1
Authority
HK
Hong Kong
Prior art keywords
protein conjugates
polysaccharide protein
derivatized polysaccharide
multivalent meningococcal
corresponding vaccines
Prior art date
Application number
HK15105208.0A
Other languages
English (en)
Inventor
Robert P Ryall
Original Assignee
Sanofi Pasteur Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Inc filed Critical Sanofi Pasteur Inc
Publication of HK1204574A1 publication Critical patent/HK1204574A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
HK15105208.0A 2003-05-07 2015-06-01 多價腦膜炎球菌衍生的多糖-蛋白質綴合物及疫苗 HK1204574A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46858103P 2003-05-07 2003-05-07

Publications (1)

Publication Number Publication Date
HK1204574A1 true HK1204574A1 (zh) 2015-11-27

Family

ID=33476662

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15105208.0A HK1204574A1 (zh) 2003-05-07 2015-06-01 多價腦膜炎球菌衍生的多糖-蛋白質綴合物及疫苗

Country Status (9)

Country Link
US (1) US20050002957A1 (zh)
EP (2) EP2386313A1 (zh)
JP (3) JP2006528936A (zh)
CN (2) CN1852733A (zh)
AU (2) AU2004240558A1 (zh)
BR (1) BRPI0410341B8 (zh)
CA (1) CA2524860C (zh)
HK (1) HK1204574A1 (zh)
WO (1) WO2004103400A2 (zh)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
EP2289546A3 (en) 2003-01-30 2011-03-30 Novartis Vaccines and Diagnostics S.r.l. Injectable vaccines against multiple meningococcal serogroups
GB0406013D0 (en) * 2004-03-17 2004-04-21 Chiron Srl Analysis of saccharide vaccines without interference
SI1740217T1 (sl) * 2004-04-30 2011-10-28 Novartis Ag Konjugirano meningokokno cepljenje
GB0500787D0 (en) 2005-01-14 2005-02-23 Chiron Srl Integration of meningococcal conjugate vaccination
JP2008517876A (ja) * 2004-08-30 2008-05-29 サノフィ パストゥール インコーポレイテッド 髄膜炎菌由来の誘導体化多糖類−タンパク質の多価コンジュゲートおよびワクチン
CA2580693A1 (en) * 2004-09-21 2006-03-30 Sanofi Pasteur, Inc. Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine
GB0513071D0 (en) * 2005-06-27 2005-08-03 Glaxosmithkline Biolog Sa Immunogenic composition
SI2283857T1 (sl) 2005-06-27 2019-11-29 Glaxosmithkline Biologicals Sa Sestava cepiva, ki obsega konjugirane nativne kapsularne polisaharide n. meningitidis
US7955817B2 (en) 2005-09-02 2011-06-07 Glaxosmithkline Biologicals S.A. Vaccine protection assay
EP1922546B1 (en) * 2005-09-05 2010-10-20 GlaxoSmithKline Biologicals S.A. Serum bactericidal assay for n. meningitidis specific antisera
EP1993604B1 (en) * 2006-03-17 2015-12-02 The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services Methods for preparing complex multivalent immunogenic conjugates
PT2004225E (pt) * 2006-03-22 2012-05-30 Novartis Ag Regimes para imunização com conjugados meningocócicos
US10828361B2 (en) * 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
EP2007427A4 (en) 2006-04-11 2012-04-04 Yeda Res & Dev IMPROVED VACCINES COMPRISING PEPTIDE MULTIPLE MEDIA DERIVED FROM HSP60
US7491517B2 (en) * 2006-07-19 2009-02-17 Jeeri R Reddy Method of producing meningococcal meningitis vaccine for Neisseria meningitidis serotypes A,C,Y, and W-135
CN101428144A (zh) * 2008-12-19 2009-05-13 长春长生生物科技股份有限公司 流脑多糖联合疫苗及制备工艺
ES2550853T3 (es) * 2010-05-03 2015-11-12 Dcb-Usa Llc Conjugación de polisacárido con enterotoxina termolábil (LT) de E. coli desintoxicada usada como vacuna
CN103623401A (zh) * 2012-08-23 2014-03-12 北京科兴中维生物技术有限公司 多价肺炎球菌荚膜多糖-蛋白质共轭组合物及其制备方法
CN102861326A (zh) * 2012-09-19 2013-01-09 天津康希诺生物技术有限公司 流脑多糖-蛋白质缀合疫苗及制备方法
CN104829711B (zh) * 2014-04-08 2018-04-03 北京天成新脉生物技术有限公司 脑膜炎球菌荚膜多糖单克隆抗体及其应用
PT3506935T (pt) 2016-09-02 2024-04-01 Sanofi Pasteur Inc Vacina contra neisseria meningitidis
CN108743936B (zh) * 2018-06-14 2022-03-15 中国科学院过程工程研究所 一种细菌多糖结合疫苗及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356170A (en) 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4619828A (en) 1982-07-06 1986-10-28 Connaught Laboratories, Inc. Polysaccharide exotoxoid conjugate vaccines
WO1990014837A1 (en) 1989-05-25 1990-12-13 Chiron Corporation Adjuvant formulation comprising a submicron oil droplet emulsion
US5153312A (en) 1990-09-28 1992-10-06 American Cyanamid Company Oligosaccharide conjugate vaccines
US5422427A (en) 1991-09-17 1995-06-06 The United States Of America As Represented By The United States Department Of Health And Human Services Pneumococcal fimbrial protein A
US5445817A (en) 1992-08-21 1995-08-29 The United States Of America As Represented By The Department Of Health And Human Services Pertussis toxin used as a carrier protein with non-charged saccharides in conjugate vaccines
US5965714A (en) * 1997-10-02 1999-10-12 Connaught Laboratories, Inc. Method for the covalent attachment of polysaccharides to protein molecules
US6146902A (en) 1998-12-29 2000-11-14 Aventis Pasteur, Inc. Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
WO2002091998A2 (en) * 2001-05-11 2002-11-21 Aventis Pasteur, Inc. Novel meningitis conjugate vaccine

Also Published As

Publication number Publication date
WO2004103400A3 (en) 2005-03-24
JP2014193929A (ja) 2014-10-09
JP2006528936A (ja) 2006-12-28
BRPI0410341A (pt) 2006-05-30
AU2004240558A1 (en) 2004-12-02
CA2524860A1 (en) 2004-12-02
WO2004103400A2 (en) 2004-12-02
EP1624888A2 (en) 2006-02-15
JP2011042693A (ja) 2011-03-03
US20050002957A1 (en) 2005-01-06
CN104225587B (zh) 2017-07-21
CN104225587A (zh) 2014-12-24
AU2010257242A1 (en) 2011-01-13
CN1852733A (zh) 2006-10-25
EP1624888B1 (en) 2016-10-12
BRPI0410341B8 (pt) 2021-05-25
EP2386313A1 (en) 2011-11-16
BRPI0410341B1 (pt) 2019-07-16
CA2524860C (en) 2016-09-13

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Effective date: 20240502