HK1203981A1 - Coagulation factor viii with reduced immunogenicity viii - Google Patents

Coagulation factor viii with reduced immunogenicity viii

Info

Publication number
HK1203981A1
HK1203981A1 HK15104600.7A HK15104600A HK1203981A1 HK 1203981 A1 HK1203981 A1 HK 1203981A1 HK 15104600 A HK15104600 A HK 15104600A HK 1203981 A1 HK1203981 A1 HK 1203981A1
Authority
HK
Hong Kong
Prior art keywords
viii
coagulation factor
reduced immunogenicity
factor viii
immunogenicity
Prior art date
Application number
HK15104600.7A
Other languages
English (en)
Chinese (zh)
Inventor
Jean-Marie Saint-Remy
Original Assignee
Imnate Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imnate Sarl filed Critical Imnate Sarl
Publication of HK1203981A1 publication Critical patent/HK1203981A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/37Factors VIII
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/20Ingredients acting on or related to the structure
    • A23V2200/218Coagulant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood
    • A61M2202/0445Proteins
    • A61M2202/0447Glycoproteins
    • A61M2202/0452Factor VIII

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK15104600.7A 2012-05-22 2015-05-14 Coagulation factor viii with reduced immunogenicity viii HK1203981A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12168800.6A EP2666782A1 (en) 2012-05-22 2012-05-22 Coagulation factor VIII with reduced immunogenicity.
PCT/EP2013/060397 WO2013174805A1 (en) 2012-05-22 2013-05-21 Coagulation factor viii with reduced immunogenicity

Publications (1)

Publication Number Publication Date
HK1203981A1 true HK1203981A1 (en) 2015-11-06

Family

ID=48485166

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15104600.7A HK1203981A1 (en) 2012-05-22 2015-05-14 Coagulation factor viii with reduced immunogenicity viii

Country Status (12)

Country Link
US (1) US10087233B2 (ru)
EP (2) EP2666782A1 (ru)
JP (1) JP6363996B2 (ru)
AU (1) AU2013265400B2 (ru)
BR (1) BR112014028575B1 (ru)
CA (1) CA2872938C (ru)
DK (1) DK2852609T3 (ru)
ES (1) ES2751361T3 (ru)
HK (1) HK1203981A1 (ru)
IN (1) IN2014DN09216A (ru)
RU (1) RU2631801C2 (ru)
WO (1) WO2013174805A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3388447A1 (en) * 2017-04-14 2018-10-17 Imnate Sarl Methods to produce peptides, polypeptides or cells for modulating immunity
EP3936867A1 (en) 2020-07-06 2022-01-12 Imnate Sarl Cd1 peptide-epitope for use in the treatment of a disease caused by an intracellular pathogen

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7084251B1 (en) * 1987-02-12 2006-08-01 Genentech, Inc. Methods and Deoxyribonucleic acid for the preparation of tissue factor protein
US5859204A (en) * 1992-04-07 1999-01-12 Emory University Modified factor VIII
WO1995006737A1 (en) * 1993-09-03 1995-03-09 Kenneth Francis Prendergast Glycophorin binding protein (gbp130) fusion compositions
US6458563B1 (en) * 1996-06-26 2002-10-01 Emory University Modified factor VIII
MXPA04010061A (es) * 2002-04-18 2004-12-13 Merck Patent Gmbh Factor viii modificado.
PT2371856T (pt) 2004-11-12 2022-08-12 Bayer Healthcare Llc Modificação de fviii direcionada a sítio
WO2006103298A2 (en) * 2005-04-01 2006-10-05 Novo Nordisk Health Care Ag Blood coagulation fviii analogues
US20090110861A1 (en) 2007-10-29 2009-04-30 3M Innovative Properties Company Pressure sensitive adhesive article
CA2703948A1 (en) * 2007-11-01 2009-05-07 University Of Rochester Recombinant factor viii having increased stability
EP3075391A1 (en) 2008-02-14 2016-10-05 Life Sciences Research Partners VZW Strategies to prevent and/or treat immune responses to soluble allofactors
EP2149603A1 (en) * 2008-07-28 2010-02-03 DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH Factor IX variants with clotting activity in absence of their cofactor and their use for treating bleeding disorders
US8691211B2 (en) * 2009-03-10 2014-04-08 Puget Sound Blood Center Suppression of immune response to factor VIII in hemophilia A patients
CA2780761A1 (en) * 2009-11-13 2011-05-19 Puget Sound Blood Center Factor viii t cell epitope variants having reduced immunogenicity
ES2663862T3 (es) * 2010-11-25 2018-04-17 Imnate Sarl Modulación de inmunogenicidad de antígeno mediante la eliminación de epítopos reconocidos por linfocitos NKT

Also Published As

Publication number Publication date
CA2872938C (en) 2020-06-16
EP2666782A1 (en) 2013-11-27
AU2013265400A1 (en) 2014-11-13
AU2013265400B2 (en) 2017-07-27
BR112014028575B1 (pt) 2022-08-30
US10087233B2 (en) 2018-10-02
DK2852609T3 (da) 2019-11-25
JP2015518844A (ja) 2015-07-06
EP2852609A1 (en) 2015-04-01
RU2631801C2 (ru) 2017-09-26
CA2872938A1 (en) 2013-11-28
JP6363996B2 (ja) 2018-07-25
IN2014DN09216A (ru) 2015-07-10
WO2013174805A1 (en) 2013-11-28
ES2751361T3 (es) 2020-03-31
RU2014151719A (ru) 2016-07-10
US20150087593A1 (en) 2015-03-26
BR112014028575A2 (pt) 2017-08-01
EP2852609B1 (en) 2019-10-09

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