HK1202309A1 - Brown adipocyte progenitors in human skeletal muscle - Google Patents

Brown adipocyte progenitors in human skeletal muscle

Info

Publication number
HK1202309A1
HK1202309A1 HK15102764.3A HK15102764A HK1202309A1 HK 1202309 A1 HK1202309 A1 HK 1202309A1 HK 15102764 A HK15102764 A HK 15102764A HK 1202309 A1 HK1202309 A1 HK 1202309A1
Authority
HK
Hong Kong
Prior art keywords
skeletal muscle
human skeletal
brown adipocyte
adipocyte progenitors
progenitors
Prior art date
Application number
HK15102764.3A
Other languages
English (en)
Chinese (zh)
Inventor
奧利弗‧
‧博斯
米哈埃拉‧克里桑
讓-保羅‧賈科比諾
Original Assignee
Energesis Pharmaceuticals Inc
Boss Olivier
Crisan Mihaela
Giacobino Jean Paul
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Energesis Pharmaceuticals Inc, Boss Olivier, Crisan Mihaela, Giacobino Jean Paul filed Critical Energesis Pharmaceuticals Inc
Publication of HK1202309A1 publication Critical patent/HK1202309A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70589—CD45
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
HK15102764.3A 2011-11-10 2015-03-17 Brown adipocyte progenitors in human skeletal muscle HK1202309A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161558152P 2011-11-10 2011-11-10
PCT/US2012/064389 WO2013071063A1 (en) 2011-11-10 2012-11-09 Brown adipocyte progenitors in human skeletal muscle

Publications (1)

Publication Number Publication Date
HK1202309A1 true HK1202309A1 (en) 2015-09-25

Family

ID=48290582

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15102764.3A HK1202309A1 (en) 2011-11-10 2015-03-17 Brown adipocyte progenitors in human skeletal muscle

Country Status (9)

Country Link
US (3) US10301595B2 (xx)
EP (1) EP2776557A4 (xx)
JP (1) JP2015502742A (xx)
CN (1) CN104066836A (xx)
AU (1) AU2012335548A1 (xx)
CA (1) CA2867922A1 (xx)
HK (1) HK1202309A1 (xx)
IL (1) IL232402A0 (xx)
WO (2) WO2013071050A1 (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015502742A (ja) 2011-11-10 2015-01-29 エネジェシス ファーマシューティカルズ，インク． ヒト骨格筋中の褐色脂肪細胞前駆細胞
US11419916B2 (en) 2012-09-11 2022-08-23 Energesis Pharmaceuticals, Inc. Methods and compositions for inducing differentiation of human brown adipocyte progenitors
EP3110946B1 (en) * 2014-02-24 2021-09-01 Energesis Pharmaceuticals Inc. Methods and compositions for inducing differentiation of human brown adipocyte progenitors
CN107638569A (zh) * 2016-07-21 2018-01-30 上海聿健生物科技有限公司 增强褐色脂肪细胞产热效率的方法和应用
JP6923111B2 (ja) * 2017-02-27 2021-08-18 ポーラ化成工業株式会社 皮膚老化改善剤のスクリーニング方法
US20200362303A1 (en) * 2017-11-30 2020-11-19 Kyoto University Maintenance-and-amplification method and differentiation induction method for primordial germ cells/primordial germ cell-like cells
JP2020143008A (ja) * 2019-03-05 2020-09-10 達也 楠堂 新規褐色脂肪細胞分化誘導剤
JPWO2022059601A1 (xx) * 2020-09-16 2022-03-24

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE448481T1 (de) 2001-07-17 2009-11-15 Teijin Ltd Selektionsverfahren für eine durch das austesten einer ppard aktivierenden wirkung charakterisierten substanz und arzneistoff
WO2007019107A2 (en) * 2005-07-29 2007-02-15 University Of Virginia Patent Foundation Adipose tissue stem cells, perivascular cells and pericytes
KR20080056182A (ko) 2005-09-02 2008-06-20 에이전시 포 사이언스, 테크놀로지 앤드 리서치 간엽 줄기 세포의 유도 방법
US20070264239A1 (en) 2006-05-10 2007-11-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Isolation of pericytes
US20100015104A1 (en) * 2006-07-26 2010-01-21 Cytori Therapeutics, Inc Generation of adipose tissue and adipocytes
US9074012B2 (en) * 2006-10-18 2015-07-07 Dana-Farber Cancer Institute, Inc. Molecular control of brown fat differentiation and energy expenditure
EP2283119B1 (en) * 2008-05-06 2015-01-07 Joslin Diabetes Center, Inc. Methods and compositions for inducing brown adipogenesis
CA2763548C (en) * 2008-05-27 2019-01-15 Energesis Pharmaceuticals, Inc. Brown adipocyte progenitors in human skeletal muscle
JP2015502742A (ja) 2011-11-10 2015-01-29 エネジェシス ファーマシューティカルズ，インク． ヒト骨格筋中の褐色脂肪細胞前駆細胞

Also Published As

Publication number Publication date
AU2012335548A1 (en) 2014-05-22
US20220228119A1 (en) 2022-07-21
EP2776557A4 (en) 2015-04-08
EP2776557A1 (en) 2014-09-17
JP2015502742A (ja) 2015-01-29
US11299710B2 (en) 2022-04-12
WO2013071063A1 (en) 2013-05-16
WO2013071050A1 (en) 2013-05-16
US20200347353A1 (en) 2020-11-05
US10301595B2 (en) 2019-05-28
CN104066836A (zh) 2014-09-24
CA2867922A1 (en) 2013-05-16
IL232402A0 (en) 2014-06-30
US20150240206A1 (en) 2015-08-27

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