HK1201763A1 - Polyamine enhanced formulations for triptan compound iontophoresis - Google Patents

Polyamine enhanced formulations for triptan compound iontophoresis

Info

Publication number
HK1201763A1
HK1201763A1 HK15102214.9A HK15102214A HK1201763A1 HK 1201763 A1 HK1201763 A1 HK 1201763A1 HK 15102214 A HK15102214 A HK 15102214A HK 1201763 A1 HK1201763 A1 HK 1201763A1
Authority
HK
Hong Kong
Prior art keywords
iontophoresis
triptan compound
enhanced formulations
polyamine
polyamine enhanced
Prior art date
Application number
HK15102214.9A
Other languages
English (en)
Chinese (zh)
Inventor
‧塞布里
‧霍斯特曼
‧薩米提
Original Assignee
Nupathe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nupathe Inc filed Critical Nupathe Inc
Publication of HK1201763A1 publication Critical patent/HK1201763A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15102214.9A 2008-06-19 2015-03-04 Polyamine enhanced formulations for triptan compound iontophoresis HK1201763A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/214,555 US8366600B2 (en) 2008-06-19 2008-06-19 Polyamine enhanced formulations for triptan compound iontophoresis

Publications (1)

Publication Number Publication Date
HK1201763A1 true HK1201763A1 (en) 2015-09-11

Family

ID=41431954

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15102214.9A HK1201763A1 (en) 2008-06-19 2015-03-04 Polyamine enhanced formulations for triptan compound iontophoresis

Country Status (12)

Country Link
US (3) US8366600B2 (xx)
EP (1) EP2296597A4 (xx)
JP (2) JP5931439B2 (xx)
CN (2) CN102065807B (xx)
AU (2) AU2008358026B2 (xx)
CA (1) CA2727926A1 (xx)
EA (2) EA023339B1 (xx)
HK (1) HK1201763A1 (xx)
IL (1) IL209755A (xx)
MX (1) MX2010013645A (xx)
WO (1) WO2009154648A1 (xx)
ZA (1) ZA201008859B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3308777A1 (en) * 2008-06-19 2018-04-18 LTS Lohmann Therapie-Systeme AG Composition for transdermal delivery of cationic active agents
US8845612B2 (en) * 2009-08-10 2014-09-30 Nupathe Inc. Methods for iontophoretically treating nausea and migraine
ES2955255T3 (es) 2016-03-25 2023-11-29 Aminex Therapeutics Inc Poliaminas biodisponibles
WO2018006069A1 (en) 2016-06-30 2018-01-04 Teva Pharmaceuticals International Gmbh Improved formulations for transdermal pharmaceutical systems
BR112020010146A2 (pt) 2017-12-20 2020-10-13 Lts Lohmann Therapie-Systeme Ag composição frigoestável para fornecimento transdérmico iontoforético de um composto de triptano
EP3727330A1 (en) * 2017-12-20 2020-10-28 LTS Lohmann Therapie-Systeme AG Frigostable composition for iontophoretic transdermal delivery of a triptan compound
JP2023545674A (ja) 2020-09-30 2023-10-31 アミネックス セラピューティクス， インコーポレイテッド ポリアミン輸送阻害剤およびｄｆｍｏの配合原薬

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US5605536A (en) 1983-08-18 1997-02-25 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US5651768A (en) 1983-08-18 1997-07-29 Drug Delivery Systems, Inc. Transdermal drug applicator and electrodes therefor
US4822802A (en) 1987-02-24 1989-04-18 Alza Corporation Method of fentanly administration for postoperative pain relief
US4927408A (en) 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5207752A (en) 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
DE4014913C2 (de) 1990-05-10 1996-05-15 Lohmann Therapie Syst Lts Miniaturisiertes transdermales therapeutisches System für die Iontophorese
ATE160510T1 (de) 1992-06-02 1997-12-15 Alza Corp Abgabevorrichtung zur elektrischen übertragung von arzneimitteln
US5807571A (en) 1993-05-06 1998-09-15 Lts Lohmann Therapie-Systeme Gmbh Transdermal therapeutic systems for administering indole serotonin agonists
US5458569A (en) 1993-06-08 1995-10-17 Becton Dickinson And Company Wearable iontophoresis system
US5533971A (en) 1993-09-03 1996-07-09 Alza Corporation Reduction of skin irritation during electrotransport
EP0643981B1 (en) * 1993-09-22 2002-01-09 Hisamitsu Pharmaceutical Co., Inc. A matrix for iontophoreses
US5697896A (en) 1994-12-08 1997-12-16 Alza Corporation Electrotransport delivery device
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US6425892B2 (en) 1995-06-05 2002-07-30 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
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US5941843A (en) 1996-07-12 1999-08-24 Empi, Inc. Iontophoresis electrode
US5882677A (en) * 1997-09-30 1999-03-16 Becton Dickinson And Company Iontophoretic patch with hydrogel reservoir
DE19828273B4 (de) * 1998-06-25 2005-02-24 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren
SE9802864D0 (sv) 1998-08-27 1998-08-27 Pharmacia & Upjohn Ab Transdermally administered tolterodine as antimuscarinic agent for the treatment of overactive bladder
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DE10035891A1 (de) * 2000-07-24 2002-02-14 Lohmann Therapie Syst Lts Medizinischer Haftkleber mit einer zweiphasigen Klebermatrix aus Polyacrylaten und Polyaminsalzen
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US20030065285A1 (en) * 2001-07-23 2003-04-03 Higuchi William I. Method and apparatus for increasing flux during reverse iontophoresis
AU2003280136A1 (en) 2002-06-28 2004-01-19 Alza Corporation A reservoir for use in an electrotransport drug delivery device
US6745071B1 (en) 2003-02-21 2004-06-01 Birch Point Medical, Inc. Iontophoretic drug delivery system
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Also Published As

Publication number Publication date
ZA201008859B (en) 2016-03-30
JP2014237675A (ja) 2014-12-18
AU2008358026B2 (en) 2015-06-18
EP2296597A4 (en) 2013-10-16
CN102065807B (zh) 2014-06-25
JP2011524901A (ja) 2011-09-08
WO2009154648A1 (en) 2009-12-23
US20130245535A1 (en) 2013-09-19
AU2008358026A1 (en) 2009-12-23
IL209755A0 (en) 2011-02-28
JP5931439B2 (ja) 2016-06-08
US8366600B2 (en) 2013-02-05
IL209755A (en) 2014-06-30
EA201100055A1 (ru) 2011-08-30
AU2015224400B2 (en) 2017-06-01
AU2015224400A1 (en) 2015-10-29
US20090318847A1 (en) 2009-12-24
CA2727926A1 (en) 2009-12-23
EA201590907A1 (ru) 2016-02-29
MX2010013645A (es) 2011-02-15
JP6002179B2 (ja) 2016-10-05
EP2296597A1 (en) 2011-03-23
EA023339B1 (ru) 2016-05-31
EA026988B1 (ru) 2017-06-30
CN104027885A (zh) 2014-09-10
US20170112779A1 (en) 2017-04-27
CN102065807A (zh) 2011-05-18

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