HK1201763A1 - Polyamine enhanced formulations for triptan compound iontophoresis - Google Patents

Polyamine enhanced formulations for triptan compound iontophoresis

Info

Publication number
HK1201763A1
HK1201763A1 HK15102214.9A HK15102214A HK1201763A1 HK 1201763 A1 HK1201763 A1 HK 1201763A1 HK 15102214 A HK15102214 A HK 15102214A HK 1201763 A1 HK1201763 A1 HK 1201763A1
Authority
HK
Hong Kong
Prior art keywords
iontophoresis
triptan compound
enhanced formulations
polyamine
polyamine enhanced
Prior art date
Application number
HK15102214.9A
Other languages
English (en)
Chinese (zh)
Inventor
‧塞布里
‧霍斯特曼
‧薩米提
Original Assignee
Nupathe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nupathe Inc filed Critical Nupathe Inc
Publication of HK1201763A1 publication Critical patent/HK1201763A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrotherapy Devices (AREA)
HK15102214.9A 2008-06-19 2015-03-04 Polyamine enhanced formulations for triptan compound iontophoresis HK1201763A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/214,555 US8366600B2 (en) 2008-06-19 2008-06-19 Polyamine enhanced formulations for triptan compound iontophoresis

Publications (1)

Publication Number Publication Date
HK1201763A1 true HK1201763A1 (en) 2015-09-11

Family

ID=41431954

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15102214.9A HK1201763A1 (en) 2008-06-19 2015-03-04 Polyamine enhanced formulations for triptan compound iontophoresis

Country Status (12)

Country Link
US (3) US8366600B2 (de)
EP (1) EP2296597A4 (de)
JP (2) JP5931439B2 (de)
CN (2) CN102065807B (de)
AU (2) AU2008358026B2 (de)
CA (1) CA2727926A1 (de)
EA (2) EA023339B1 (de)
HK (1) HK1201763A1 (de)
IL (1) IL209755A (de)
MX (1) MX2010013645A (de)
WO (1) WO2009154648A1 (de)
ZA (1) ZA201008859B (de)

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* Cited by examiner, † Cited by third party
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EP2285362B1 (de) * 2008-06-19 2017-08-09 LTS LOHMANN Therapie-Systeme AG Zusammensetzung zur transdermalen verabreichung kationischer wirkstoffe
NZ598622A (en) * 2009-08-10 2014-02-28 Nupathe Inc Methods for iontophoretically treating nausea and migraine
EA037149B1 (ru) * 2016-03-25 2021-02-11 Аминекс Терапьютикс, Инк. Биодоступные полиамины
WO2018006069A1 (en) 2016-06-30 2018-01-04 Teva Pharmaceuticals International Gmbh Improved formulations for transdermal pharmaceutical systems
EP3727330A1 (de) 2017-12-20 2020-10-28 LTS Lohmann Therapie-Systeme AG Einfrierstabile zusammensetzung zur iontophoretischen transdermalen abgabe einer triptanverbindung
CA3086494A1 (en) 2017-12-20 2019-06-27 Lts Lohmann Therapie-Systeme Ag Frigostable composition for iontophoretic transdermal delivery of a triptan compound
EP4221698A1 (de) 2020-09-30 2023-08-09 Aminex Therapeutics, Inc. Kombinationswirkstoff aus einem polyamintransporthemmer und dfmo
IL303390A (en) 2020-12-03 2023-08-01 Battelle Memorial Institute Compositions of polymer nanoparticles and DNA nanostructures and methods for non-viral transport
AU2022253899A1 (en) 2021-04-07 2023-10-26 Battelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers

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US5651768A (en) 1983-08-18 1997-07-29 Drug Delivery Systems, Inc. Transdermal drug applicator and electrodes therefor
US5605536A (en) 1983-08-18 1997-02-25 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US4822802A (en) 1987-02-24 1989-04-18 Alza Corporation Method of fentanly administration for postoperative pain relief
US4927408A (en) 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system
EP0429842B1 (de) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5207752A (en) 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
DE4014913C2 (de) 1990-05-10 1996-05-15 Lohmann Therapie Syst Lts Miniaturisiertes transdermales therapeutisches System für die Iontophorese
ATE160510T1 (de) 1992-06-02 1997-12-15 Alza Corp Abgabevorrichtung zur elektrischen übertragung von arzneimitteln
US5807571A (en) 1993-05-06 1998-09-15 Lts Lohmann Therapie-Systeme Gmbh Transdermal therapeutic systems for administering indole serotonin agonists
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DE69429603T2 (de) * 1993-09-22 2002-08-14 Hisamitsu Pharmaceutical Co., Inc. Iontophoresematrix
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US5882677A (en) * 1997-09-30 1999-03-16 Becton Dickinson And Company Iontophoretic patch with hydrogel reservoir
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Also Published As

Publication number Publication date
AU2015224400A1 (en) 2015-10-29
JP6002179B2 (ja) 2016-10-05
JP2014237675A (ja) 2014-12-18
CA2727926A1 (en) 2009-12-23
US20170112779A1 (en) 2017-04-27
IL209755A0 (en) 2011-02-28
EA023339B1 (ru) 2016-05-31
US8366600B2 (en) 2013-02-05
AU2015224400B2 (en) 2017-06-01
AU2008358026A1 (en) 2009-12-23
JP2011524901A (ja) 2011-09-08
EA201590907A1 (ru) 2016-02-29
ZA201008859B (en) 2016-03-30
EP2296597A1 (de) 2011-03-23
EP2296597A4 (de) 2013-10-16
AU2008358026B2 (en) 2015-06-18
JP5931439B2 (ja) 2016-06-08
MX2010013645A (es) 2011-02-15
WO2009154648A1 (en) 2009-12-23
CN104027885A (zh) 2014-09-10
EA201100055A1 (ru) 2011-08-30
CN102065807A (zh) 2011-05-18
IL209755A (en) 2014-06-30
EA026988B1 (ru) 2017-06-30
US20090318847A1 (en) 2009-12-24
CN102065807B (zh) 2014-06-25
US20130245535A1 (en) 2013-09-19

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