HK1201063A1 - 製備他汀含硫前體的方法 - Google Patents

製備他汀含硫前體的方法

Info

Publication number
HK1201063A1
HK1201063A1 HK15101521.9A HK15101521A HK1201063A1 HK 1201063 A1 HK1201063 A1 HK 1201063A1 HK 15101521 A HK15101521 A HK 15101521A HK 1201063 A1 HK1201063 A1 HK 1201063A1
Authority
HK
Hong Kong
Prior art keywords
thioprecursor
statins
preparation
Prior art date
Application number
HK15101521.9A
Other languages
English (en)
Inventor
本.藍格.德
丹尼斯.海姆斯柯克
卡林.翰德威克.瑪利亞.波塞姆賓德
Original Assignee
Dsm Sinochem Pharm Nl Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Sinochem Pharm Nl Bv filed Critical Dsm Sinochem Pharm Nl Bv
Publication of HK1201063A1 publication Critical patent/HK1201063A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK15101521.9A 2011-12-09 2015-02-11 製備他汀含硫前體的方法 HK1201063A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11192749 2011-12-09
PCT/EP2012/074689 WO2013083719A1 (en) 2011-12-09 2012-12-06 Process for the preparation of a thioprecursor for statins

Publications (1)

Publication Number Publication Date
HK1201063A1 true HK1201063A1 (zh) 2015-08-21

Family

ID=47291022

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15101521.9A HK1201063A1 (zh) 2011-12-09 2015-02-11 製備他汀含硫前體的方法

Country Status (10)

Country Link
US (1) US9260423B2 (zh)
EP (1) EP2788341B1 (zh)
CN (1) CN103987705B (zh)
ES (1) ES2623495T3 (zh)
HK (1) HK1201063A1 (zh)
HU (1) HUE032936T2 (zh)
IL (1) IL232804A (zh)
MX (1) MX363563B (zh)
SI (1) SI2788341T1 (zh)
WO (1) WO2013083719A1 (zh)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3803551B2 (ja) 1998-08-05 2006-08-02 株式会社カネカ 光学活性2−[6−(ヒドロキシメチル)−1,3−ジオキサン−4−イル]酢酸誘導体の製造法
GB9903472D0 (en) 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
US20020028826A1 (en) 2000-06-15 2002-03-07 Robl Jeffrey A. HMG-CoA reductase inhibitors and method
NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
IL158525A0 (en) * 2001-06-06 2004-05-12 Bristol Myers Squibb Co A process for preparing chiral diol sulfone derivatives
ES2282433T3 (es) 2001-07-12 2007-10-16 Dsm Ip Assets B.V. Procedimiento para la preparacion de 2,4-didesoxihexosas y 2,4,6-tridesoxihexosas.
CZ299215B6 (cs) 2005-06-29 2008-05-21 Zentiva, A. S. Zpusob výroby hemivápenaté soli (E)-7-[4-(4-fluorofenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl] (3R,5S)-3,5-dihydroxy-6-heptenovékyseliny

Also Published As

Publication number Publication date
CN103987705A (zh) 2014-08-13
WO2013083719A1 (en) 2013-06-13
SI2788341T1 (sl) 2017-06-30
EP2788341B1 (en) 2017-04-05
CN103987705B (zh) 2015-09-30
ES2623495T3 (es) 2017-07-11
MX363563B (es) 2019-03-27
EP2788341A1 (en) 2014-10-15
IL232804A0 (en) 2014-08-03
US9260423B2 (en) 2016-02-16
US20140343292A1 (en) 2014-11-20
HUE032936T2 (en) 2017-11-28
IL232804A (en) 2017-01-31
MX2014006893A (es) 2014-09-04

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