HK1199250A1 - Biaryl heterocycle substituted oxazolidinon antibacterial drug - Google Patents

Biaryl heterocycle substituted oxazolidinon antibacterial drug

Info

Publication number
HK1199250A1
HK1199250A1 HK14112754.5A HK14112754A HK1199250A1 HK 1199250 A1 HK1199250 A1 HK 1199250A1 HK 14112754 A HK14112754 A HK 14112754A HK 1199250 A1 HK1199250 A1 HK 1199250A1
Authority
HK
Hong Kong
Prior art keywords
oxazolidinon
heterocycle substituted
antibacterial drug
biaryl
biaryl heterocycle
Prior art date
Application number
HK14112754.5A
Other languages
English (en)
Chinese (zh)
Inventor
吳永謙
王愛臣
Original Assignee
Xuanzhu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xuanzhu Pharma Co Ltd filed Critical Xuanzhu Pharma Co Ltd
Publication of HK1199250A1 publication Critical patent/HK1199250A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/04Nitro compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK14112754.5A 2011-09-29 2014-12-19 Biaryl heterocycle substituted oxazolidinon antibacterial drug HK1199250A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110290839 2011-09-29
PCT/CN2012/082318 WO2013044845A1 (zh) 2011-09-29 2012-09-28 联芳基杂环取代的噁唑烷酮抗菌药

Publications (1)

Publication Number Publication Date
HK1199250A1 true HK1199250A1 (en) 2015-06-26

Family

ID=47994272

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14112754.5A HK1199250A1 (en) 2011-09-29 2014-12-19 Biaryl heterocycle substituted oxazolidinon antibacterial drug

Country Status (8)

Country Link
US (1) US9359344B2 (ja)
EP (1) EP2762479A4 (ja)
JP (1) JP5796134B2 (ja)
KR (1) KR101629115B1 (ja)
CN (1) CN103030635B (ja)
HK (1) HK1199250A1 (ja)
UA (1) UA112876C2 (ja)
WO (1) WO2013044845A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103975931B (zh) * 2014-06-04 2015-08-19 吴文君 一类二氢噻唑类化合物作为农用杀菌剂的用途
CN106928214A (zh) * 2014-09-17 2017-07-07 博瑞生物医药(苏州)股份有限公司 一种噁唑烷酮类化合物及其中间体的制备方法
CN105524008B (zh) * 2014-10-21 2018-09-07 山东轩竹医药科技有限公司 噁唑烷酮抗菌药中间体的制备方法
CN111560014A (zh) * 2020-05-13 2020-08-21 河南科技大学第一附属医院 一种杀菌消毒所用噁唑链接三唑类药物分子及其制备方法和应用
CA3183397A1 (en) 2020-06-18 2021-12-23 Daryl C. Drummond Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and methods of use thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0873455A (ja) * 1994-03-15 1996-03-19 Upjohn Co:The オキサゾリジノン誘導体及びこれを有効成分とする医薬組成物
CA2294293A1 (en) * 1997-07-11 1999-01-21 Pharmacia & Upjohn Company Thiadiazolyl and oxadiazolyl phenyl oxazolidinone antibacterial agents
HUP0301562A2 (hu) * 2000-06-05 2003-12-29 Dong A Pharm. Co., Ltd. Új oxazolidinonszármazékok és eljárás ezek előállítására, ezeket tartalmazó gyógyszerkészítmények
CA2415965A1 (en) 2000-07-17 2002-01-24 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
BR0215921A (pt) * 2002-07-29 2005-09-13 Ranbaxy Lab Ltd Derivados de oxazolidinona utilizáveis como antimicrobianos e processo de sua preparação
AU2004267007C1 (en) * 2003-06-03 2010-04-29 Melinta Subsidiary Corp. Biaryl heterocyclic compounds and methods of making and using the same
SI1656370T1 (sl) * 2003-06-03 2012-12-31 Rib-X Pharmaceuticals, Inc. Biarilne heterociklične spojine in postopki za njihovo izdelavo in uporabo
US7687627B2 (en) 2003-09-08 2010-03-30 Wockhardt Limited Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
WO2005082899A1 (en) * 2004-01-28 2005-09-09 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
US7666864B2 (en) * 2008-03-26 2010-02-23 Global Alliance For Tb Drug Development Bicyclic nitroimidazole-substituted phenyl oxazolidinones
CN101560209B (zh) * 2008-04-15 2011-09-14 沈阳中海药业有限公司 含有嘧啶的噁唑烷酮类化合物及其制备方法
JPWO2009157423A1 (ja) * 2008-06-24 2011-12-15 財団法人乙卯研究所 縮合環を有するオキサゾリジノン誘導体
CN102153547A (zh) * 2010-02-11 2011-08-17 山东轩竹医药科技有限公司 含有并环的噁唑烷酮抗菌素
CN102190656B (zh) * 2010-03-16 2014-03-26 山东轩竹医药科技有限公司 含有五元杂环的噁唑烷酮抗菌素
CN102276595A (zh) * 2010-04-16 2011-12-14 山东轩竹医药科技有限公司 含有五元杂环的噁唑烷酮抗菌素

Also Published As

Publication number Publication date
CN103030635B (zh) 2015-11-25
KR20140054396A (ko) 2014-05-08
EP2762479A4 (en) 2015-04-22
CN103030635A (zh) 2013-04-10
US20140235584A1 (en) 2014-08-21
WO2013044845A1 (zh) 2013-04-04
UA112876C2 (uk) 2016-11-10
US9359344B2 (en) 2016-06-07
KR101629115B1 (ko) 2016-06-09
JP5796134B2 (ja) 2015-10-21
EP2762479A1 (en) 2014-08-06
JP2014528946A (ja) 2014-10-30

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