HK1198166A1 - Imidazolidinedione compounds and their uses - Google Patents
Imidazolidinedione compounds and their usesInfo
- Publication number
- HK1198166A1 HK1198166A1 HK14111671A HK14111671A HK1198166A1 HK 1198166 A1 HK1198166 A1 HK 1198166A1 HK 14111671 A HK14111671 A HK 14111671A HK 14111671 A HK14111671 A HK 14111671A HK 1198166 A1 HK1198166 A1 HK 1198166A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- imidazolidinedione compounds
- imidazolidinedione
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011104188590A CN103159680A (zh) | 2011-12-14 | 2011-12-14 | 咪唑二酮类化合物及其用途 |
| PCT/CN2012/086573 WO2013087004A1 (fr) | 2011-12-14 | 2012-12-13 | Composés d'imidazolidinedione et leurs utilisations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1198166A1 true HK1198166A1 (en) | 2015-03-13 |
Family
ID=48583248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK14111671A HK1198166A1 (en) | 2011-12-14 | 2014-11-19 | Imidazolidinedione compounds and their uses |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9346764B2 (fr) |
| EP (1) | EP2792674B1 (fr) |
| JP (1) | JP5933746B2 (fr) |
| CN (2) | CN103159680A (fr) |
| AU (1) | AU2012350482B2 (fr) |
| CA (1) | CA2859224C (fr) |
| ES (1) | ES2587903T3 (fr) |
| HK (1) | HK1198166A1 (fr) |
| PL (1) | PL2792674T3 (fr) |
| WO (1) | WO2013087004A1 (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3020714B1 (fr) * | 2013-05-29 | 2022-12-28 | Hinova Pharmaceuticals Inc. | Composé imidazole-dicétone et son utilisation |
| US20160228446A1 (en) * | 2013-09-19 | 2016-08-11 | GlaxoSmithKline LLCC | Combination Drug Therapy |
| CN105188699B (zh) * | 2013-10-14 | 2017-04-26 | 杭州普晒医药科技有限公司 | 恩杂鲁胺的固态形式及其制备方法和用途 |
| CN104803919A (zh) * | 2014-01-26 | 2015-07-29 | 上海医药工业研究院 | 用于制备恩杂鲁胺中间体的方法 |
| WO2016051423A2 (fr) * | 2014-10-01 | 2016-04-07 | Laurus Labs Private Limited | Procédé amélioré de préparation d'enzalutamide |
| CN106432090B (zh) * | 2015-10-30 | 2019-08-20 | 成都海创药业有限公司 | 一种氘代咪唑酮化合物的晶型及其制备方法和用途 |
| CN107303278B (zh) * | 2016-04-25 | 2020-11-13 | 成都海创药业有限公司 | 一种hc-1119固体分散体及其制备方法 |
| CN107954936B (zh) * | 2016-10-17 | 2021-03-19 | 海创药业股份有限公司 | 一种制备氘代咪唑二酮类化合物的方法 |
| EP3581182B1 (fr) * | 2017-02-13 | 2021-09-29 | Kangpu Biopharmaceuticals, Ltd. | Association médicamenteuse pour le traitement du cancer de la prostate, composition pharmaceutique et méthode de traitement |
| WO2019025250A1 (fr) | 2017-08-04 | 2019-02-07 | Basf Se | Trifluorométhyloxadiazoles substitués permettant de lutter contre des champignons phytopathogènes |
| WO2019184952A1 (fr) * | 2018-03-29 | 2019-10-03 | Hinova Pharmaceuticals Inc. | Composés d'imidazolidinedione deutérés et leurs utilisations |
| CA3096963A1 (fr) * | 2018-04-13 | 2019-10-17 | Hinova Pharmaceuticals Inc. | Nouveau procede de synthese d'amides deuteres et de sulfonamides deuteres |
| US20210290553A1 (en) * | 2018-05-14 | 2021-09-23 | Hinova Pharmaceuticals Inc. | Hc-1119 formulation, preparation method and use thereof |
| US20210386826A1 (en) | 2018-11-05 | 2021-12-16 | Pfizer Inc. | Combination for Treating Cancer |
| CN112442009B (zh) * | 2019-08-30 | 2023-10-03 | 润佳（苏州）医药科技有限公司 | 氘代化合物及其在治疗癌症方面的应用 |
| US20230158152A1 (en) * | 2020-03-17 | 2023-05-25 | Medshine Discovery Inc. | Proteolysis regulator and method for using same |
| CN116322693A (zh) | 2020-08-13 | 2023-06-23 | 辉瑞公司 | 组合疗法 |
| CN114181155A (zh) * | 2021-12-21 | 2022-03-15 | 上海朝晖药业有限公司 | 碘-恩杂鲁胺及其制备方法及其应用 |
| CN115181043B (zh) * | 2022-07-27 | 2024-05-07 | 爱斯特（成都）生物制药股份有限公司 | 一种连续流制备4-异硫氰基-2-(三氟甲基)苯甲腈的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2444085E (pt) * | 2005-05-13 | 2015-06-11 | Univ California | Compostos de diaril-hidantoínas como antagonistas do recetor androgénio para tratamento de cancro |
| PL2656841T3 (pl) * | 2006-03-27 | 2017-01-31 | The Regents Of The University Of California | Modulator receptora androgenowego do leczenia raka gruczołu krokowego i chorób związanych z receptorem androgenowym |
| EP2439196A1 (fr) * | 2006-03-29 | 2012-04-11 | The Regents of The University of California | Composés de diarylthiohydantoïne destinés à être utilisés dans une méthode de traitement d'une maladie hyperproliférative |
| CN101817787B (zh) * | 2009-02-26 | 2013-07-24 | 童友之 | 抗前列腺癌的雄性激素受体拮抗剂 |
| CN102482230B (zh) | 2009-09-10 | 2016-01-06 | 苏州开拓药业有限公司 | 雄激素受体拮抗剂及其用途 |
| WO2013067151A1 (fr) * | 2011-11-02 | 2013-05-10 | Medivation Prostate Therapeutics, Inc. | Procédés de traitement utilisant des dérivés de diarylthiohydantoïne |
-
2011
- 2011-12-14 CN CN2011104188590A patent/CN103159680A/zh active Pending
-
2012
- 2012-12-13 WO PCT/CN2012/086573 patent/WO2013087004A1/fr active Application Filing
- 2012-12-13 CN CN201280052853.9A patent/CN104024228B/zh active Active
- 2012-12-13 JP JP2014546301A patent/JP5933746B2/ja active Active
- 2012-12-13 CA CA2859224A patent/CA2859224C/fr active Active
- 2012-12-13 PL PL12858174.1T patent/PL2792674T3/pl unknown
- 2012-12-13 AU AU2012350482A patent/AU2012350482B2/en active Active
- 2012-12-13 EP EP12858174.1A patent/EP2792674B1/fr active Active
- 2012-12-13 ES ES12858174.1T patent/ES2587903T3/es active Active
- 2012-12-13 US US14/364,147 patent/US9346764B2/en active Active
-
2014
- 2014-11-19 HK HK14111671A patent/HK1198166A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2792674B1 (fr) | 2016-05-25 |
| ES2587903T3 (es) | 2016-10-27 |
| WO2013087004A1 (fr) | 2013-06-20 |
| CA2859224C (fr) | 2019-03-19 |
| JP2015501820A (ja) | 2015-01-19 |
| EP2792674A1 (fr) | 2014-10-22 |
| CN104024228A (zh) | 2014-09-03 |
| CN104024228B (zh) | 2015-07-08 |
| AU2012350482B2 (en) | 2017-02-16 |
| EP2792674A4 (fr) | 2015-06-17 |
| AU2012350482A1 (en) | 2014-07-10 |
| US20140371284A1 (en) | 2014-12-18 |
| US9346764B2 (en) | 2016-05-24 |
| JP5933746B2 (ja) | 2016-06-15 |
| CN103159680A (zh) | 2013-06-19 |
| CA2859224A1 (fr) | 2013-06-20 |
| PL2792674T3 (pl) | 2016-12-30 |
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