HK1186722A1 - 種從紅曲中分離的化合物、其製備方法及用途 - Google Patents

種從紅曲中分離的化合物、其製備方法及用途

Info

Publication number
HK1186722A1
HK1186722A1 HK13114058.5A HK13114058A HK1186722A1 HK 1186722 A1 HK1186722 A1 HK 1186722A1 HK 13114058 A HK13114058 A HK 13114058A HK 1186722 A1 HK1186722 A1 HK 1186722A1
Authority
HK
Hong Kong
Prior art keywords
preparation
method therefor
compound isolated
monascus purpureus
purpureus
Prior art date
Application number
HK13114058.5A
Other languages
English (en)
Inventor
段震文
郭樹仁
李雪梅
劉春麗
Original Assignee
北京北大維信生物科技有限公司 號
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 北京北大維信生物科技有限公司 號 filed Critical 北京北大維信生物科技有限公司 號
Publication of HK1186722A1 publication Critical patent/HK1186722A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
HK13114058.5A 2011-02-01 2013-12-19 種從紅曲中分離的化合物、其製備方法及用途 HK1186722A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110033924.8A CN102617533B (zh) 2011-02-01 2011-02-01 一种从红曲中分离的化合物、其制备方法及用途
PCT/CN2012/070169 WO2012103777A1 (zh) 2011-02-01 2012-01-10 一种从红曲中分离的化合物、其制备方法及用途

Publications (1)

Publication Number Publication Date
HK1186722A1 true HK1186722A1 (zh) 2014-03-21

Family

ID=46557793

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13114058.5A HK1186722A1 (zh) 2011-02-01 2013-12-19 種從紅曲中分離的化合物、其製備方法及用途

Country Status (9)

Country Link
US (1) US9371304B2 (zh)
JP (2) JP6130303B2 (zh)
CN (2) CN102617533B (zh)
CA (1) CA2826178C (zh)
HK (1) HK1186722A1 (zh)
MY (1) MY167897A (zh)
SG (1) SG192241A1 (zh)
TW (1) TWI432420B (zh)
WO (1) WO2012103777A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10889612B2 (en) 2011-12-26 2021-01-12 Beijing Peking University Wbl Biotech Co., Ltd. Sterol derivatives and preparation method and uses thereof
CN102836569B (zh) * 2012-08-21 2015-01-07 西北农林科技大学 一种万年蒿挥发油提取工艺
CN105985244A (zh) * 2015-02-04 2016-10-05 北京北大维信生物科技有限公司 化合物、其分离方法、合成方法及用途
CN105566268B (zh) * 2016-03-09 2017-12-08 福州大学 一种红曲洛伐他汀的纯化制备方法
CN113640448B (zh) * 2021-08-30 2024-06-18 西藏月王药诊生态藏药科技有限公司 一种藏红曲的质量控制方法和构建方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BG61613B1 (bg) 1994-06-24 1998-01-30 Анна Куюмджиева Щам моnаsсus рurрurеus-продуцент на пигмент и биоактивни продукти
US6046022A (en) * 1996-09-30 2000-04-04 Peking University Methods and compositions employing red rice fermentation products
US7238348B2 (en) 1996-09-30 2007-07-03 Beijing Peking University Wbl Corporation Ltd. Method of treatment of osteoporosis with compositions of red rice fermentation products
US6376476B1 (en) * 1996-12-13 2002-04-23 Zymogenetics Corporation Isoprenoid pathway inhibitors for stimulating bone growth
CO5140104A1 (es) * 1999-02-16 2002-03-22 Novartis Ag Derivados de mevinolina y preparacion farmaceuticas que los contienen
JP2005333973A (ja) * 2004-05-28 2005-12-08 Nippon Medicine:Kk イソフラボンアグリコン含有食品素材およびその製造法
CN100455295C (zh) * 2005-07-22 2009-01-28 北京北大维信生物科技有限公司 一种用红曲制成的滴丸及其制备方法
CN100342861C (zh) * 2005-10-11 2007-10-17 李朝晖 一种红曲提取物及其制剂
CN101104003A (zh) * 2006-07-11 2008-01-16 北京北大维信生物科技有限公司 血脂康特制红曲的抗癌新用途
CN101113146B (zh) * 2006-07-27 2010-05-12 北京北大维信生物科技有限公司 血脂康特制红曲有效成分的分离方法
CN101313919B (zh) * 2007-05-31 2012-08-08 北京北大维信生物科技有限公司 一种红曲提取物及其制备方法和质量检测方法
CN101584716B (zh) * 2009-04-10 2012-05-23 昆明法莫泰克生物技术有限公司 红曲提取物油及其软胶囊的制备和应用

Also Published As

Publication number Publication date
SG192241A1 (en) 2013-09-30
TW201309661A (zh) 2013-03-01
WO2012103777A1 (zh) 2012-08-09
CN102617533B (zh) 2014-08-27
US9371304B2 (en) 2016-06-21
JP6130303B2 (ja) 2017-05-17
CA2826178A1 (en) 2012-08-09
CN102617533A (zh) 2012-08-01
JP2017105795A (ja) 2017-06-15
JP2014512338A (ja) 2014-05-22
JP6302102B2 (ja) 2018-03-28
CN103339121A (zh) 2013-10-02
MY167897A (en) 2018-09-26
US20130310450A1 (en) 2013-11-21
CN103339121B (zh) 2016-04-13
CA2826178C (en) 2019-10-22
TWI432420B (zh) 2014-04-01

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