HK1184434A1 - 用於製備取代的 -氨基- -甲基戊烷- -基 苯基化合物的方法 - Google Patents
用於製備取代的 -氨基- -甲基戊烷- -基 苯基化合物的方法Info
- Publication number
- HK1184434A1 HK1184434A1 HK13111244.6A HK13111244A HK1184434A1 HK 1184434 A1 HK1184434 A1 HK 1184434A1 HK 13111244 A HK13111244 A HK 13111244A HK 1184434 A1 HK1184434 A1 HK 1184434A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methylpentane
- amino
- substituted
- preparation
- phenyl compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10006201 | 2010-06-15 | ||
| PCT/EP2011/002904 WO2011157390A2 (en) | 2010-06-15 | 2011-06-14 | Process for the preparation of substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1184434A1 true HK1184434A1 (zh) | 2014-01-24 |
Family
ID=43086453
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK13111244.6A HK1184434A1 (zh) | 2010-06-15 | 2013-10-03 | 用於製備取代的 -氨基- -甲基戊烷- -基 苯基化合物的方法 |
| HK15103620.5A HK1203069A1 (zh) | 2010-06-15 | 2013-10-03 | 用於製備取代的 -氨基- -甲基戊烷- -基 苯基化合物的方法 |
| HK15112413.7A HK1211568A1 (zh) | 2010-06-15 | 2015-12-17 | 用於製備取代的 -氨基- -甲基戊烷- -基 苯基化合物的方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15103620.5A HK1203069A1 (zh) | 2010-06-15 | 2013-10-03 | 用於製備取代的 -氨基- -甲基戊烷- -基 苯基化合物的方法 |
| HK15112413.7A HK1211568A1 (zh) | 2010-06-15 | 2015-12-17 | 用於製備取代的 -氨基- -甲基戊烷- -基 苯基化合物的方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8669399B2 (zh) |
| EP (3) | EP2666765B1 (zh) |
| CN (3) | CN104725246B (zh) |
| HK (3) | HK1184434A1 (zh) |
| IL (4) | IL221925A (zh) |
| WO (1) | WO2011157390A2 (zh) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102617501A (zh) * | 2011-01-31 | 2012-08-01 | 中国科学院上海药物研究所 | 取代正戊酰胺类化合物、其制备方法及用途 |
| WO2013016840A1 (zh) * | 2011-07-29 | 2013-02-07 | 安徽省新星药物开发有限责任公司 | 用于合成他喷他多或其类似物的新中间体 |
| EP2674414A1 (en) | 2012-06-15 | 2013-12-18 | Siegfried AG | Method for the preparation of 1-aryl-1-alkyl-3-dialkylaminopropane compounds |
| CN102936205B (zh) * | 2012-11-12 | 2014-06-18 | 合肥市新星医药化工有限公司 | 一种他喷他多的合成方法 |
| US9090539B2 (en) * | 2013-05-24 | 2015-07-28 | Ampac Fine Chemicals Llc | Compounds and methods for preparing substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds |
| CZ307492B6 (cs) | 2014-02-04 | 2018-10-17 | Zentiva, K.S. | Pevná forma maleátu tapentadolu a způsob její přípravy |
| ES2940904T3 (es) | 2014-07-10 | 2023-05-12 | SpecGx LLC | Procedimiento para preparar fenilalcanos sustituidos |
| US20170233330A1 (en) * | 2014-08-11 | 2017-08-17 | Sandoz Ag | Process for the preparation of 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]-phenol |
| EP3995492B1 (en) * | 2015-07-10 | 2024-05-29 | SpecGx LLC | A two-step process for preparing 3-substituted phenylalkylamines |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| SE0004827D0 (sv) * | 2000-12-22 | 2000-12-22 | Astrazeneca Ab | Therapeutic compounds |
| DE10326097A1 (de) * | 2003-06-06 | 2005-01-05 | Grünenthal GmbH | Verfahren zur Herstellung von Dimethyl-(3-aryl-butyl)-aminverbindungen |
| WO2005061467A2 (en) * | 2003-06-20 | 2005-07-07 | Amgen Inc. | Piperazine derivatives as bradykinin antagonists |
| DE10328316A1 (de) * | 2003-06-23 | 2005-01-20 | Grünenthal GmbH | Verfahren zur Herstellung von Dimethyl-(3-aryl-buthyl)-aminverbindungen als pharmazeutische Wirkstoffe |
| WO2007139230A1 (ja) * | 2006-05-31 | 2007-12-06 | Asubio Pharma Co., Ltd. | ７員環化合物並びにその製造法および医薬用途 |
| TWI496762B (zh) | 2006-07-24 | 2015-08-21 | 製備（１ｒ，２ｒ）-３-（３-二甲胺基-１-乙基-２-甲基-丙基）-酚之方法 | |
| TWI401237B (zh) * | 2006-07-24 | 2013-07-11 | ３-〔（１ｒ，２ｒ）-３-（二甲基氨基）-１-乙基-２-甲基丙基〕酚之製備 | |
| CN102711461A (zh) * | 2009-12-29 | 2012-10-03 | Mapi医药公司 | 用于制备他喷他多及相关化合物的中间体化合物和方法 |
-
2011
- 2011-06-14 US US13/160,050 patent/US8669399B2/en active Active
- 2011-06-14 EP EP13004106.4A patent/EP2666765B1/en active Active
- 2011-06-14 CN CN201510024860.3A patent/CN104725246B/zh active Active
- 2011-06-14 CN CN201180029409.0A patent/CN103168025B/zh active Active
- 2011-06-14 WO PCT/EP2011/002904 patent/WO2011157390A2/en active Application Filing
- 2011-06-14 EP EP14002207.0A patent/EP2792668B1/en active Active
- 2011-06-14 EP EP11733993.7A patent/EP2582659B1/en active Active
- 2011-06-14 CN CN201510024698.5A patent/CN104725245A/zh active Pending
-
2012
- 2012-09-13 IL IL221925A patent/IL221925A/en active IP Right Grant
-
2013
- 2013-08-21 US US13/972,253 patent/US9388119B2/en active Active
- 2013-10-03 HK HK13111244.6A patent/HK1184434A1/zh unknown
- 2013-10-03 HK HK15103620.5A patent/HK1203069A1/zh unknown
-
2014
- 2014-04-29 IL IL232318A patent/IL232318A/en active IP Right Grant
- 2014-04-29 IL IL232319A patent/IL232319B/en active IP Right Grant
-
2015
- 2015-12-17 HK HK15112413.7A patent/HK1211568A1/zh unknown
-
2016
- 2016-05-17 US US15/157,216 patent/US9850198B2/en active Active
-
2018
- 2018-03-08 IL IL257977A patent/IL257977A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2792668B1 (en) | 2017-05-31 |
| EP2582659A2 (en) | 2013-04-24 |
| CN104725245A (zh) | 2015-06-24 |
| IL232319B (en) | 2018-05-31 |
| CN103168025A (zh) | 2013-06-19 |
| US9388119B2 (en) | 2016-07-12 |
| US20130338399A1 (en) | 2013-12-19 |
| US8669399B2 (en) | 2014-03-11 |
| US9850198B2 (en) | 2017-12-26 |
| US20160257640A1 (en) | 2016-09-08 |
| CN104725246A (zh) | 2015-06-24 |
| WO2011157390A2 (en) | 2011-12-22 |
| WO2011157390A3 (en) | 2012-03-15 |
| EP2666765A3 (en) | 2013-12-11 |
| CN104725246B (zh) | 2017-05-03 |
| CN103168025B (zh) | 2015-02-25 |
| EP2792668A1 (en) | 2014-10-22 |
| EP2582659B1 (en) | 2015-03-11 |
| IL257977A (en) | 2018-05-31 |
| IL232319A0 (en) | 2014-06-30 |
| EP2666765A2 (en) | 2013-11-27 |
| IL232318A0 (en) | 2014-06-30 |
| IL232318A (en) | 2017-01-31 |
| HK1203069A1 (zh) | 2015-10-16 |
| EP2666765B1 (en) | 2017-01-04 |
| HK1211568A1 (zh) | 2016-05-27 |
| US20110306793A1 (en) | 2011-12-15 |
| IL221925A (en) | 2015-06-30 |
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