HK1183863A1 - 用於製備免疫佐劑的化合物 - Google Patents
用於製備免疫佐劑的化合物Info
- Publication number
- HK1183863A1 HK1183863A1 HK13111246.4A HK13111246A HK1183863A1 HK 1183863 A1 HK1183863 A1 HK 1183863A1 HK 13111246 A HK13111246 A HK 13111246A HK 1183863 A1 HK1183863 A1 HK 1183863A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- compounds
- immunological adjuvant
- preparing immunological
- preparing
- adjuvant
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000568 immunological adjuvant Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/141—Esters of phosphorous acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/141—Esters of phosphorous acids
- C07F9/1411—Esters of phosphorous acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2408—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyalkyl compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69532405P | 2005-06-30 | 2005-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1183863A1 true HK1183863A1 (zh) | 2014-01-10 |
Family
ID=37192315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK13111246.4A HK1183863A1 (zh) | 2005-06-30 | 2013-10-03 | 用於製備免疫佐劑的化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7683200B2 (zh) |
| EP (3) | EP1910387B1 (zh) |
| JP (3) | JP5214446B2 (zh) |
| KR (1) | KR101294455B1 (zh) |
| CN (3) | CN103012304B (zh) |
| AU (1) | AU2006265986B2 (zh) |
| CA (1) | CA2611721C (zh) |
| HK (1) | HK1183863A1 (zh) |
| IL (3) | IL187819A (zh) |
| WO (1) | WO2007005583A1 (zh) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040006242A1 (en) * | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
| US7915238B2 (en) * | 1999-02-01 | 2011-03-29 | Eisai R & D Management Co., Ltd. | Immunomodulatory compounds and methods of use thereof |
| CA2611721C (en) | 2005-06-30 | 2014-04-22 | Eisai Co., Ltd. | Compounds for preparing immunological adjuvant |
| RU2494091C2 (ru) * | 2007-12-18 | 2013-09-27 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Реагенты и способы для бета-кетоамидного синтеза синтетического предшественника иммунологического адъюванта е6020 |
| EP2515940A4 (en) | 2009-12-22 | 2013-10-09 | Sanofi Pasteur Ltd | IMMUNOGENIC COMPOSITIONS AND CORRESPONDING METHODS |
| KR101857839B1 (ko) * | 2010-09-30 | 2018-05-14 | 유로씨네 백신즈 에이비 | 개선된 백신 조성물들 |
| US9327021B2 (en) | 2010-11-15 | 2016-05-03 | Sanofi Pasteur Limited | Immunogenic compositions |
| WO2012075428A1 (en) | 2010-12-03 | 2012-06-07 | Sanofi Pasteur Limited | Composition for immunization against streptococcus pneumoniae |
| WO2013184900A2 (en) | 2012-06-06 | 2013-12-12 | Sanofi Pasteur Biologics, Llc | Immunogenic compositions and related methods |
| AU2013332272B2 (en) * | 2012-10-19 | 2018-12-20 | The Council Of The Queensland Institute Of Medical Research | Improved human herpesvirus immunotherapy |
| WO2014070687A2 (en) | 2012-10-29 | 2014-05-08 | Molecular Transfer, Inc. | Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells |
| EP2742952A1 (en) | 2012-12-17 | 2014-06-18 | Eurocine Vaccines AB | Influenza vaccine composition |
| CN105339346B (zh) * | 2013-02-25 | 2017-03-08 | 斯克里普斯研究学院 | Neoseptin：小分子佐剂 |
| US11039620B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US11039621B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US9622483B2 (en) | 2014-02-19 | 2017-04-18 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| WO2017064190A1 (en) | 2015-10-13 | 2017-04-20 | Sanofi Pasteur | Immunogenic compositions against s. aureus |
| WO2017137085A1 (en) | 2016-02-11 | 2017-08-17 | Sanofi Pasteur | Meningitidis vaccines comprising subtilinases |
| US20230149537A1 (en) * | 2020-04-06 | 2023-05-18 | Eisai R&D Management Co., Ltd. | Vaccines, adjuvants, and methods of generating an immune response |
| KR20230097028A (ko) | 2020-10-28 | 2023-06-30 | 사노피 파스퇴르 | Tlr4 효현제를 함유하는 리포좀, 이의 제조 및 용도 |
| WO2023056089A1 (en) | 2021-10-03 | 2023-04-06 | Eisai R&D Management Co., Ltd. | Immunological adjuvant formulations comprising tlr4 agonist e6020 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993004672A1 (en) * | 1991-09-11 | 1993-03-18 | Pitman-Moore, Inc. | Method for enhancing the immune system in a host employing liposome-encapsulated polypeptides |
| AU5543294A (en) * | 1993-10-29 | 1995-05-22 | Pharmos Corp. | Submicron emulsions as vaccine adjuvants |
| EP1147117B1 (en) * | 1999-02-01 | 2004-06-16 | Eisai Co., Ltd. | Immunological adjuvant compounds |
| US6551600B2 (en) | 1999-02-01 | 2003-04-22 | Eisai Co., Ltd. | Immunological adjuvant compounds compositions and methods of use thereof |
| US6835721B2 (en) * | 1999-02-01 | 2004-12-28 | Eisai Co., Ltd. | Immunomodulatory compounds and methods of use thereof |
| US20040006242A1 (en) * | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
| JP2002544170A (ja) * | 1999-05-06 | 2002-12-24 | ジェネティックス・インスチチュート・インコーポレーテッド | 免疫応答を高めるための可溶性同時刺激分子の使用 |
| ATE310008T1 (de) | 2000-07-31 | 2005-12-15 | Eisai Co Ltd | Immunologische adjuvans verbindungen |
| BR0215643A (pt) * | 2002-03-05 | 2004-12-21 | Cell Medicine Inc | Adjuvante imunológico de tecido solidificado |
| CN1535726A (zh) * | 2003-04-11 | 2004-10-13 | 上海欣安基因免疫与疫苗研究开发有限 | 一种分子佐剂、其制备方法以及含该分子佐剂的基因疫苗 |
| CA2611721C (en) * | 2005-06-30 | 2014-04-22 | Eisai Co., Ltd. | Compounds for preparing immunological adjuvant |
-
2006
- 2006-06-30 CA CA2611721A patent/CA2611721C/en active Active
- 2006-06-30 CN CN201210358141.1A patent/CN103012304B/zh active Active
- 2006-06-30 JP JP2008519603A patent/JP5214446B2/ja active Active
- 2006-06-30 CN CN201210359517.0A patent/CN103012169B/zh active Active
- 2006-06-30 EP EP06785934.8A patent/EP1910387B1/en active Active
- 2006-06-30 WO PCT/US2006/025536 patent/WO2007005583A1/en active Application Filing
- 2006-06-30 KR KR1020087002446A patent/KR101294455B1/ko active IP Right Grant
- 2006-06-30 AU AU2006265986A patent/AU2006265986B2/en active Active
- 2006-06-30 US US11/477,936 patent/US7683200B2/en active Active
- 2006-06-30 EP EP16192172.1A patent/EP3138844B1/en active Active
- 2006-06-30 CN CN2006800239637A patent/CN101213199B/zh active Active
- 2006-06-30 EP EP10012396A patent/EP2292628A3/en not_active Withdrawn
-
2007
- 2007-12-02 IL IL187819A patent/IL187819A/en active IP Right Grant
-
2010
- 2010-02-02 US US12/698,686 patent/US8198474B2/en active Active
-
2011
- 2011-05-26 IL IL213174A patent/IL213174A/en active IP Right Grant
- 2011-05-26 IL IL213173A patent/IL213173A0/en active IP Right Grant
-
2012
- 2012-04-20 JP JP2012096962A patent/JP5923373B2/ja active Active
- 2012-05-10 US US13/468,634 patent/US8519170B2/en active Active
-
2013
- 2013-07-22 US US13/947,593 patent/US8754236B2/en active Active
- 2013-10-03 HK HK13111246.4A patent/HK1183863A1/zh unknown
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2014
- 2014-05-05 US US14/269,659 patent/US8962857B2/en active Active
- 2014-10-07 JP JP2014206710A patent/JP2015051978A/ja not_active Withdrawn
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