HK1180767A1 - An assay for measurement of antibodies binding to a therapeutic monoclonal antibody - Google Patents

An assay for measurement of antibodies binding to a therapeutic monoclonal antibody

Info

Publication number
HK1180767A1
HK1180767A1 HK13107981.1A HK13107981A HK1180767A1 HK 1180767 A1 HK1180767 A1 HK 1180767A1 HK 13107981 A HK13107981 A HK 13107981A HK 1180767 A1 HK1180767 A1 HK 1180767A1
Authority
HK
Hong Kong
Prior art keywords
assay
measurement
monoclonal antibody
antibodies binding
therapeutic monoclonal
Prior art date
Application number
HK13107981.1A
Other languages
English (en)
Chinese (zh)
Inventor
Veit Peter Grunert
Ursula Klause
Pavel Kubalec
Matthias Rothfuss
Barbara Upmeier
Original Assignee
霍夫曼-拉羅奇有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 霍夫曼-拉羅奇有限公司 filed Critical 霍夫曼-拉羅奇有限公司
Publication of HK1180767A1 publication Critical patent/HK1180767A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK13107981.1A 2010-08-19 2013-07-09 An assay for measurement of antibodies binding to a therapeutic monoclonal antibody HK1180767A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10173408 2010-08-19
PCT/EP2011/064178 WO2012022774A1 (en) 2010-08-19 2011-08-17 An assay for measurement of antibodies binding to a therapeutic monoclonal antibody

Publications (1)

Publication Number Publication Date
HK1180767A1 true HK1180767A1 (en) 2013-10-25

Family

ID=42727619

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13107981.1A HK1180767A1 (en) 2010-08-19 2013-07-09 An assay for measurement of antibodies binding to a therapeutic monoclonal antibody

Country Status (8)

Country Link
US (1) US9081016B2 (xx)
EP (1) EP2606362B1 (xx)
JP (1) JP5805190B2 (xx)
CN (1) CN103109190B (xx)
CA (1) CA2802278A1 (xx)
ES (1) ES2555864T3 (xx)
HK (1) HK1180767A1 (xx)
WO (1) WO2012022774A1 (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104614535B (zh) * 2015-02-10 2017-11-28 深圳市新产业生物医学工程股份有限公司 甲状腺微粒体抗体检测试剂盒及其制备方法和应用
US11119096B2 (en) * 2016-07-08 2021-09-14 W. Health L.P. Universal assay for determining the quantity of therapeutic monoclonal antibodies and their corresponding anti-drug-antibodies in samples
CN106093413A (zh) * 2016-07-18 2016-11-09 本·沙朗 一种抗英夫利西抗体elisa检测试剂盒和检测方法
CA3075900A1 (en) * 2017-09-15 2019-03-21 Beckman Coulter, Inc. Flow based assays for therapeutics
CA3094241A1 (en) * 2018-03-27 2019-10-03 Laboratory Corporation Of America Holdings Compositions and methods for identifying subjects who may benefit from treatment with therapeutic agents
CN117590002A (zh) * 2023-11-23 2024-02-23 上海领检科技有限公司 一种TNFα抗药抗体的检测方法及检测试剂盒

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Also Published As

Publication number Publication date
WO2012022774A1 (en) 2012-02-23
CN103109190B (zh) 2015-07-22
EP2606362B1 (en) 2015-09-30
JP5805190B2 (ja) 2015-11-04
JP2013536419A (ja) 2013-09-19
CA2802278A1 (en) 2012-02-23
CN103109190A (zh) 2013-05-15
ES2555864T3 (es) 2016-01-11
US9081016B2 (en) 2015-07-14
US20130157892A1 (en) 2013-06-20
EP2606362A1 (en) 2013-06-26

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