HK1179617A1 - 2,5,6,7-tetrahydro-[1,4]oxazepin-3-ylamine or 2,3,6,7-tetrahydro- [1,4]oxazepin-5-ylamine compounds 2567--[14]-3- 2367--[14]-5- - Google Patents

2,5,6,7-tetrahydro-[1,4]oxazepin-3-ylamine or 2,3,6,7-tetrahydro- [1,4]oxazepin-5-ylamine compounds 2567--[14]-3- 2367--[14]-5-

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Publication number
HK1179617A1
HK1179617A1 HK13106766.4A HK13106766A HK1179617A1 HK 1179617 A1 HK1179617 A1 HK 1179617A1 HK 13106766 A HK13106766 A HK 13106766A HK 1179617 A1 HK1179617 A1 HK 1179617A1
Authority
HK
Hong Kong
Prior art keywords
oxazepin
tetrahydro
ylamine
compounds
ylamine compounds
Prior art date
Application number
HK13106766.4A
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English (en)
Chinese (zh)
Inventor
戴維．班納
沃爾夫岡．古帕
漢斯．希爾珀特
羅蘭．胡姆
哈拉爾德．莫塞
亞歷山大．
．邁韋格
羅伯特．納爾基齊昂
約恩．鮑爾
馬克．羅杰斯-埃文斯
迪迪埃．羅姆巴赫
托馬斯．沃爾特林
沃爾夫岡．沃斯特
Original Assignee
霍夫曼-拉羅奇有限公司
錫耶納生物技術股份公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 霍夫曼-拉羅奇有限公司, 錫耶納生物技術股份公司 filed Critical 霍夫曼-拉羅奇有限公司
Publication of HK1179617A1 publication Critical patent/HK1179617A1/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/10—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK13106766.4A 2010-05-07 2013-06-07 2,5,6,7-tetrahydro-[1,4]oxazepin-3-ylamine or 2,3,6,7-tetrahydro- [1,4]oxazepin-5-ylamine compounds 2567--[14]-3- 2367--[14]-5- HK1179617A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10162340 2010-05-07
PCT/EP2011/056990 WO2011138293A1 (en) 2010-05-07 2011-05-03 2,5,6,7-tetrahydro-[1,4]oxazepin-3-ylamine or 2,3,6,7-tetrahydro-[1,4]oxazepin-5-ylamine compounds

Publications (1)

Publication Number Publication Date
HK1179617A1 true HK1179617A1 (en) 2013-10-04

Family

ID=44168838

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13106766.4A HK1179617A1 (en) 2010-05-07 2013-06-07 2,5,6,7-tetrahydro-[1,4]oxazepin-3-ylamine or 2,3,6,7-tetrahydro- [1,4]oxazepin-5-ylamine compounds 2567--[14]-3- 2367--[14]-5-

Country Status (14)

Country Link
US (2) US8673894B2 (xx)
EP (1) EP2566855B1 (xx)
JP (1) JP5823503B2 (xx)
KR (1) KR20130100241A (xx)
CN (1) CN102958922B (xx)
AR (1) AR081369A1 (xx)
BR (1) BR112012028519A2 (xx)
CA (1) CA2797622A1 (xx)
ES (1) ES2481409T3 (xx)
HK (1) HK1179617A1 (xx)
MX (1) MX2012012952A (xx)
RU (1) RU2570796C2 (xx)
TW (1) TW201144302A (xx)
WO (1) WO2011138293A1 (xx)

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EP2360155A4 (en) 2008-10-22 2012-06-20 Shionogi & Co 2-AMINOPYRIDIN-4-ON AND 2-AMINOPYRIDINE DERIVATIVE WITH BACE1-HEMDERING EFFECT
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CN102834384A (zh) 2009-12-11 2012-12-19 盐野义制药株式会社 *嗪衍生物
WO2012057248A1 (ja) 2010-10-29 2012-05-03 塩野義製薬株式会社 ナフチリジン誘導体
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KR20140010031A (ko) * 2011-01-13 2014-01-23 노파르티스 아게 대사 장애의 치료를 위한 ｂａｃｅ-2 억제제
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JP2014524472A (ja) 2011-08-22 2014-09-22 メルク・シャープ・アンド・ドーム・コーポレーション Ｂａｃｅ阻害剤としての２−スピロ置換イミノチアジンならびにそのモノオキシドおよびジオキシド、組成物、ならびにそれらの使用
CA2851445A1 (en) 2011-10-13 2013-04-18 Novartis Ag Novel oxazine derivatives and their use in the treatment of disease
US8338413B1 (en) 2012-03-07 2012-12-25 Novartis Ag Oxazine derivatives and their use in the treatment of neurological disorders
MX2014012683A (es) 2012-04-27 2015-01-16 Eisai R&D Man Co Ltd Metodo para producir el acido 5-(difluorometil)pirazin-2-carboxili co y un intermediario de la produccion de este.
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AR081369A1 (es) 2012-08-29
CN102958922A (zh) 2013-03-06
JP2013525506A (ja) 2013-06-20
MX2012012952A (es) 2012-12-17
US20140045820A1 (en) 2014-02-13
US8673894B2 (en) 2014-03-18
TW201144302A (en) 2011-12-16
EP2566855B1 (en) 2014-05-21
KR20130100241A (ko) 2013-09-10
CN102958922B (zh) 2015-09-30
ES2481409T3 (es) 2014-07-30
CA2797622A1 (en) 2011-11-10
RU2570796C2 (ru) 2015-12-10
EP2566855A1 (en) 2013-03-13
JP5823503B2 (ja) 2015-11-25
US20110312937A1 (en) 2011-12-22
BR112012028519A2 (pt) 2016-07-19
WO2011138293A1 (en) 2011-11-10
RU2012148818A (ru) 2014-06-20

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