HK1177458A1 - 取代的咪唑并吡啶基-氨基吡啶化合物 - Google Patents

取代的咪唑并吡啶基-氨基吡啶化合物 Download PDF

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Publication number
HK1177458A1
HK1177458A1 HK13104562.5A HK13104562A HK1177458A1 HK 1177458 A1 HK1177458 A1 HK 1177458A1 HK 13104562 A HK13104562 A HK 13104562A HK 1177458 A1 HK1177458 A1 HK 1177458A1
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HK
Hong Kong
Prior art keywords
substituted
unsubstituted
heteroatoms selected
alkyl
butyl
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HK13104562.5A
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German (de)
English (en)
French (fr)
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HK1177458B (zh
Inventor
Mark A. Ashwell
Chris Brassard
Anton Filikov
Jason Hill
Steffi Koerner
Jean-Marc Lapierre
Yanbin Liu
Nivedita Namdev
Robert Nicewonger
Rocio Palma
Manish Tandon
David Vensel
Akihisa Matsuda
Shin Iimura
Yuko Yamamoto
Original Assignee
Arqule, Inc.
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Application filed by Arqule, Inc. filed Critical Arqule, Inc.
Publication of HK1177458A1 publication Critical patent/HK1177458A1/zh
Publication of HK1177458B publication Critical patent/HK1177458B/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
HK13104562.5A 2009-12-30 2010-12-29 取代的咪唑并吡啶基-氨基吡啶化合物 HK1177458B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29092309P 2009-12-30 2009-12-30
US61/290,923 2009-12-30
PCT/US2010/062440 WO2011082270A2 (en) 2009-12-30 2010-12-29 Substituted imidazopyridinyl-aminopyridine compounds

Publications (2)

Publication Number Publication Date
HK1177458A1 true HK1177458A1 (zh) 2013-08-23
HK1177458B HK1177458B (zh) 2015-08-14

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Also Published As

Publication number Publication date
CN102781940B (zh) 2016-09-07
WO2011082270A3 (en) 2011-11-17
JP5774602B2 (ja) 2015-09-09
RU2619463C2 (ru) 2017-05-16
JP2013516419A (ja) 2013-05-13
ES2531109T3 (es) 2015-03-10
TW201132640A (en) 2011-10-01
BR112012016398B1 (pt) 2021-12-21
TWI585086B (zh) 2017-06-01
CA2785536A1 (en) 2011-07-07
EP2519522A4 (en) 2013-03-13
PH12012501323A1 (en) 2014-12-17
BR112012016398A2 (pt) 2018-08-21
DK2519522T3 (en) 2014-12-08
KR101689421B1 (ko) 2016-12-23
AU2010339533A1 (en) 2012-07-12
AU2010339533B2 (en) 2015-05-07
NZ600801A (en) 2013-09-27
US8501770B2 (en) 2013-08-06
RU2012132444A (ru) 2014-02-10
CN102781940A (zh) 2012-11-14
CO6511271A2 (es) 2012-08-31
WO2011082270A2 (en) 2011-07-07
SG181947A1 (en) 2012-07-30
US20110172203A1 (en) 2011-07-14
EP2519522B1 (en) 2014-09-24
EP2519522A2 (en) 2012-11-07
KR20120120271A (ko) 2012-11-01
CA2785536C (en) 2018-02-27
IL220571A (en) 2015-03-31
MX2012007367A (es) 2013-04-03
MY157124A (en) 2016-05-13

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