HK1174895A1 - 花生四烯酸類似物及用其進行鎮痛治療的方法 - Google Patents
花生四烯酸類似物及用其進行鎮痛治療的方法Info
- Publication number
- HK1174895A1 HK1174895A1 HK13102048.3A HK13102048A HK1174895A1 HK 1174895 A1 HK1174895 A1 HK 1174895A1 HK 13102048 A HK13102048 A HK 13102048A HK 1174895 A1 HK1174895 A1 HK 1174895A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- same
- arachidonic acid
- acid analogs
- analgesic treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/09—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26443409P | 2009-11-25 | 2009-11-25 | |
| PCT/US2010/058041 WO2011066414A1 (en) | 2009-11-25 | 2010-11-24 | Arachidonic acid analogs and methods for analgesic treatment using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1174895A1 true HK1174895A1 (zh) | 2013-06-21 |
Family
ID=43478049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK13102048.3A HK1174895A1 (zh) | 2009-11-25 | 2013-02-18 | 花生四烯酸類似物及用其進行鎮痛治療的方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8658632B2 (zh) |
| EP (1) | EP2504311B1 (zh) |
| JP (1) | JP5796909B2 (zh) |
| KR (1) | KR101865194B1 (zh) |
| CN (1) | CN102725261B (zh) |
| BR (1) | BR112012012391A2 (zh) |
| CA (1) | CA2781436C (zh) |
| DK (1) | DK2504311T3 (zh) |
| ES (1) | ES2549924T3 (zh) |
| HK (1) | HK1174895A1 (zh) |
| MX (1) | MX2012005689A (zh) |
| WO (1) | WO2011066414A1 (zh) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2208720A1 (en) * | 2009-01-13 | 2010-07-21 | Max-Delbrück-Centrum für Molekulare Medizin (MDC) | Novel eicosanoid derivatives |
| EP2575773A4 (en) * | 2010-05-26 | 2014-06-25 | Selecta Biosciences Inc | SYNTHETIC NANOTRÄGERKOMBINATIONSIMPFSTOFFE |
| CN103588666A (zh) * | 2013-10-26 | 2014-02-19 | 史克勇 | 一种呈高光学纯度的化合物 |
| CN103588663A (zh) * | 2013-10-26 | 2014-02-19 | 史克勇 | 癌痛药 |
| CN103588672A (zh) * | 2013-10-28 | 2014-02-19 | 史克勇 | 一种治疗癌性疼痛的药物 |
| CN103588667A (zh) * | 2013-10-28 | 2014-02-19 | 史克勇 | 一种新化合物 |
| CN106061942B (zh) | 2014-01-22 | 2019-11-15 | 分子医学马克斯德尔布吕克中心 | 新型cyp-类二十烷酸衍生物 |
| WO2016179137A1 (en) * | 2015-05-04 | 2016-11-10 | Cytometix, Inc. | Compositions and methods for delivery of polyunsaturated fatty acid derivatives and analogs |
| CA3127590A1 (en) * | 2019-01-28 | 2020-08-06 | Mitochondria Emotion, Inc. | Mitofusin activators and methods of use thereof |
| US20220387357A1 (en) * | 2021-06-04 | 2022-12-08 | Cytometix, Inc. | Method of Dosing a Pain Therapeutic |
| US11951083B2 (en) | 2022-06-08 | 2024-04-09 | Cytometix, Inc. | Methods of manufacturing 14,15-epoxyeicosatrienoic acid analogs and improved therapeutic delivery of same |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US160452A (en) | 1875-03-02 | Improvement in caps | ||
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US4777049A (en) | 1983-12-01 | 1988-10-11 | Alza Corporation | Constant release system with pulsed release |
| US4663308A (en) | 1984-07-18 | 1987-05-05 | Medical College Of Ohio | Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract |
| JPH075484B2 (ja) * | 1985-03-06 | 1995-01-25 | 帝人株式会社 | 血液脳関門通過性医薬品組成物 |
| IL103932A (en) * | 1992-11-30 | 1997-02-18 | Yissum Res & Dev | Fatty acid and pharmaceutical compositions containing them |
| GB2323594A (en) * | 1997-03-25 | 1998-09-30 | Victor Martin | 2-amino-alkanoic acid derivatives, 2-amino alcohols and diamines |
| AU1833600A (en) * | 1998-11-24 | 2000-06-19 | Andreas Goutopoulos | Cannabimimetic lipid amides as useful medications |
| JP2008506669A (ja) * | 2004-07-16 | 2008-03-06 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 神経変性疾患の処置に適するピペリジン、ピペラジンもしくはモルホリンの二量体化合物またはそれらの７−員同族体 |
| MX2007004536A (es) * | 2004-10-13 | 2007-07-17 | Univ Connecticut | Ligandos de lipido canabinergico. |
| EP2208720A1 (en) * | 2009-01-13 | 2010-07-21 | Max-Delbrück-Centrum für Molekulare Medizin (MDC) | Novel eicosanoid derivatives |
-
2010
- 2010-11-24 BR BR112012012391-2A patent/BR112012012391A2/pt not_active IP Right Cessation
- 2010-11-24 CN CN201080053564.1A patent/CN102725261B/zh active Active
- 2010-11-24 CA CA2781436A patent/CA2781436C/en active Active
- 2010-11-24 ES ES10796199.7T patent/ES2549924T3/es active Active
- 2010-11-24 JP JP2012541202A patent/JP5796909B2/ja active Active
- 2010-11-24 MX MX2012005689A patent/MX2012005689A/es active IP Right Grant
- 2010-11-24 EP EP10796199.7A patent/EP2504311B1/en active Active
- 2010-11-24 DK DK10796199.7T patent/DK2504311T3/en active
- 2010-11-24 WO PCT/US2010/058041 patent/WO2011066414A1/en active Application Filing
- 2010-11-24 KR KR1020127016567A patent/KR101865194B1/ko active IP Right Grant
-
2012
- 2012-05-25 US US13/481,333 patent/US8658632B2/en active Active
-
2013
- 2013-02-18 HK HK13102048.3A patent/HK1174895A1/zh unknown
-
2014
- 2014-01-17 US US14/158,064 patent/US9096494B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN102725261B (zh) | 2014-07-30 |
| US9096494B2 (en) | 2015-08-04 |
| DK2504311T3 (en) | 2015-11-16 |
| JP2013512255A (ja) | 2013-04-11 |
| CN102725261A (zh) | 2012-10-10 |
| WO2011066414A1 (en) | 2011-06-03 |
| US8658632B2 (en) | 2014-02-25 |
| EP2504311B1 (en) | 2015-08-12 |
| US20130023510A1 (en) | 2013-01-24 |
| EP2504311A1 (en) | 2012-10-03 |
| US20140135401A1 (en) | 2014-05-15 |
| CA2781436C (en) | 2018-01-02 |
| JP5796909B2 (ja) | 2015-10-21 |
| ES2549924T3 (es) | 2015-11-03 |
| BR112012012391A2 (pt) | 2020-10-20 |
| MX2012005689A (es) | 2012-08-31 |
| KR20120101473A (ko) | 2012-09-13 |
| KR101865194B1 (ko) | 2018-06-08 |
| CA2781436A1 (en) | 2011-06-03 |
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