ZA201303813B - Methods of treatment using lipid compounds - Google Patents

Methods of treatment using lipid compounds

Info

Publication number
ZA201303813B
ZA201303813B ZA2013/03813A ZA201303813A ZA201303813B ZA 201303813 B ZA201303813 B ZA 201303813B ZA 2013/03813 A ZA2013/03813 A ZA 2013/03813A ZA 201303813 A ZA201303813 A ZA 201303813A ZA 201303813 B ZA201303813 B ZA 201303813B
Authority
ZA
South Africa
Prior art keywords
treatment
methods
lipid compounds
lipid
compounds
Prior art date
Application number
ZA2013/03813A
Inventor
Ragnar Hovland
David A Fraser
Tore Skjaeret
Original Assignee
Pronova Biopharma Norge As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pronova Biopharma Norge As filed Critical Pronova Biopharma Norge As
Publication of ZA201303813B publication Critical patent/ZA201303813B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/60—Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
ZA2013/03813A 2010-11-05 2013-05-24 Methods of treatment using lipid compounds ZA201303813B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41044510P 2010-11-05 2010-11-05
PCT/IB2011/002925 WO2012059818A1 (en) 2010-11-05 2011-11-03 Methods of treatment using lipid compounds

Publications (1)

Publication Number Publication Date
ZA201303813B true ZA201303813B (en) 2015-06-24

Family

ID=46024069

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2013/03813A ZA201303813B (en) 2010-11-05 2013-05-24 Methods of treatment using lipid compounds

Country Status (21)

Country Link
US (1) US9394228B2 (en)
EP (1) EP2635270B1 (en)
JP (1) JP2014505017A (en)
KR (3) KR20200034814A (en)
CN (2) CN103347508A (en)
AR (1) AR083772A1 (en)
AU (1) AU2011324909B2 (en)
BR (1) BR112013010890B1 (en)
CA (1) CA2816949C (en)
CO (1) CO6771414A2 (en)
EA (1) EA028535B1 (en)
ES (1) ES2618604T3 (en)
IL (1) IL226116B (en)
MX (1) MX350720B (en)
MY (1) MY170076A (en)
NZ (1) NZ610705A (en)
SG (2) SG10201509127YA (en)
TW (2) TWI578984B (en)
UA (1) UA111475C2 (en)
WO (1) WO2012059818A1 (en)
ZA (1) ZA201303813B (en)

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EP2147910A1 (en) 2008-07-15 2010-01-27 Pronova BioPharma Norge AS Novel lipid compounds
AU2010244136B2 (en) 2009-05-08 2016-05-12 Pronova Biopharma Norge As Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas
JP2014505017A (en) 2010-11-05 2014-02-27 プロノヴァ・バイオファーマ・ノルゲ・アーエス Treatment method using lipid compounds
JP6537980B2 (en) 2013-02-28 2019-07-03 プロノヴァ・バイオファーマ・ノルゲ・アーエスＰｒｏｎｏｖａ ＢｉｏＰｈａｒｍａ Ｎｏｒｇｅ ＡＳ Composition comprising lipid compound, triglyceride and surfactant, and method of use thereof
DK2961727T3 (en) * 2013-02-28 2017-03-13 Pronova Biopharma Norge As Process for Preparation of 2 - ((5Z, 8Z, 11Z, 14Z, 17Z) -icosa-5,8,11,14,17-pentaenyloxy) -butanoic acid
JP2018510206A (en) * 2015-04-01 2018-04-12 プロノヴァ バイオファーマ ノルゲ エーエス Use of thiaoxo compounds to lower apo C3
JP7341916B2 (en) * 2015-04-01 2023-09-11 ビーエーエスエフ エーエス Use of thiaoxo compounds to lower apoC3
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MX2023007347A (en) * 2020-12-22 2023-08-16 Northsea Therapeutics B V Combination therapies comprising oxygen-containing structurally enhanced fatty acids for treatment of non-alcoholic steatohepatitis.

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Also Published As

Publication number Publication date
KR20200034814A (en) 2020-03-31
KR20130132836A (en) 2013-12-05
KR102265409B1 (en) 2021-06-16
EP2635270B1 (en) 2016-12-21
MY170076A (en) 2019-07-03
BR112013010890A2 (en) 2016-08-02
SG10201509127YA (en) 2015-12-30
TW201701875A (en) 2017-01-16
WO2012059818A1 (en) 2012-05-10
IL226116A0 (en) 2013-06-27
TW201233388A (en) 2012-08-16
TWI578984B (en) 2017-04-21
BR112013010890B1 (en) 2020-03-10
JP2014505017A (en) 2014-02-27
CA2816949A1 (en) 2012-05-10
EP2635270A1 (en) 2013-09-11
AR083772A1 (en) 2013-03-20
AU2011324909A1 (en) 2013-06-13
AU2011324909B2 (en) 2016-09-08
MX350720B (en) 2017-09-14
EA028535B1 (en) 2017-11-30
ES2618604T3 (en) 2017-06-21
UA111475C2 (en) 2016-05-10
CN107496395A (en) 2017-12-22
EA201390659A1 (en) 2013-11-29
CA2816949C (en) 2017-07-04
KR20190072661A (en) 2019-06-25
CN103347508A (en) 2013-10-09
US20130345269A1 (en) 2013-12-26
US9394228B2 (en) 2016-07-19
SG190114A1 (en) 2013-07-31
CO6771414A2 (en) 2013-10-15
IL226116B (en) 2018-01-31
EP2635270A4 (en) 2014-03-26
MX2013005022A (en) 2013-06-03
NZ610705A (en) 2014-10-31

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