HK1166988A1 - Binding member for gm-csf receptor gm-csf - Google Patents

Binding member for gm-csf receptor gm-csf

Info

Publication number
HK1166988A1
HK1166988A1 HK12107633.4A HK12107633A HK1166988A1 HK 1166988 A1 HK1166988 A1 HK 1166988A1 HK 12107633 A HK12107633 A HK 12107633A HK 1166988 A1 HK1166988 A1 HK 1166988A1
Authority
HK
Hong Kong
Prior art keywords
csf
receptor
binding member
binding members
csfr
Prior art date
Application number
HK12107633.4A
Other languages
English (en)
Inventor
Emma Cohen
Ralph Minter
Paula Harrison
Matthew Sleeman
Andrew Nash
Louis Fabri
Original Assignee
Medimmune Ltd
Zenyth Operations Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Ltd, Zenyth Operations Pty Ltd filed Critical Medimmune Ltd
Publication of HK1166988A1 publication Critical patent/HK1166988A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
HK12107633.4A 2006-03-27 2012-08-02 Binding member for gm-csf receptor gm-csf HK1166988A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78656906P 2006-03-27 2006-03-27

Publications (1)

Publication Number Publication Date
HK1166988A1 true HK1166988A1 (en) 2012-11-16

Family

ID=38293698

Family Applications (2)

Application Number Title Priority Date Filing Date
HK12107633.4A HK1166988A1 (en) 2006-03-27 2012-08-02 Binding member for gm-csf receptor gm-csf
HK12107671.7A HK1166989A1 (en) 2006-03-27 2012-08-03 Binding member for gm-csf receptor gm-csf

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK12107671.7A HK1166989A1 (en) 2006-03-27 2012-08-03 Binding member for gm-csf receptor gm-csf

Country Status (16)

Country Link
US (8) US8263075B2 (xx)
EP (3) EP1999152B1 (xx)
JP (2) JP5335662B2 (xx)
KR (2) KR101481844B1 (xx)
CN (3) CN103641915B (xx)
BR (1) BRPI0709259B1 (xx)
CA (1) CA2647449C (xx)
DK (3) DK1999152T3 (xx)
ES (3) ES2424468T3 (xx)
HK (2) HK1166988A1 (xx)
MX (2) MX348827B (xx)
PL (3) PL2423230T3 (xx)
PT (3) PT2423229E (xx)
RU (2) RU2495050C2 (xx)
SI (3) SI2423230T1 (xx)
WO (1) WO2007110631A1 (xx)

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AU2015224416B2 (en) * 2008-12-22 2017-04-20 The University Of Melbourne Osteoarthritis treatment
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CN102459340A (zh) * 2009-04-23 2012-05-16 特罗科隆科学有限公司 粒性白血细胞-巨噬细胞菌落-刺激因子(gm-csf)中和抗体
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AR093297A1 (es) 2012-10-31 2015-05-27 Amgen Res (Munich) Gmbh Formulacion liquida que comprende un compuesto neutralizante de gm-csf
EP2914289B1 (en) 2012-10-31 2019-05-22 Takeda GmbH Lyophilized formulation comprising gm-csf neutralizing compound
JP6475166B2 (ja) 2012-12-14 2019-02-27 バイオエヌテク アールエヌエー ファーマシュティカルズ ジーエムビーエイチ 新規mhc非依存性腫瘍関連抗原
CN103193882B (zh) * 2013-03-29 2014-11-05 浙江大学 胚胎干细胞特异性标志物GM-CSFRα及其应用
MX2016002177A (es) 2013-08-30 2016-06-28 Takeda Gmbh Anticuerpos neutralizantes de gm-csf para usarse en el tratamiento de artritis reumatoide o como analgesicos.
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EP3623382A1 (en) 2018-09-14 2020-03-18 Universität Zürich Ligands to gm-csf or gm-csf-receptor for use in leukemia in a patient having undergone allo-hct
US11078264B2 (en) 2018-10-17 2021-08-03 University Of Connecticut Inhibiting granulocyte macrophage-colony stimulating factor (GM-CSF) prevents preterm birth
WO2020096664A1 (en) 2018-11-09 2020-05-14 Kiniksa Pharmaceuticals, Ltd. Treatment for giant cell arteritis
WO2020097321A1 (en) 2018-11-09 2020-05-14 Kiniksa Pharmaceuticals, Ltd. Treatment for giant cell arteritis
EP3902835A4 (en) * 2018-11-27 2022-08-17 Staidson (Beijing) Biopharmaceuticals Co., Ltd. ANTIBODIES SPECIFICALLY RECOGNIZING GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR ALPHA AND THEIR USES
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US20230030680A1 (en) * 2020-01-07 2023-02-02 St. Jude Children's Research Hospital, Inc Chimeric gmcsf-il18 receptor
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Also Published As

Publication number Publication date
RU2012157042A (ru) 2014-07-10
PT2423230E (pt) 2013-08-26
ES2424467T3 (es) 2013-10-02
KR20080113262A (ko) 2008-12-29
CN101443360A (zh) 2009-05-27
KR101451546B1 (ko) 2014-10-16
BRPI0709259B1 (pt) 2022-05-31
JP5335662B2 (ja) 2013-11-06
EP2423230A1 (en) 2012-02-29
CA2647449A1 (en) 2007-10-04
CN103641915B (zh) 2017-04-12
WO2007110631A1 (en) 2007-10-04
PL2423230T3 (pl) 2013-10-31
US20090130093A1 (en) 2009-05-21
ES2424468T3 (es) 2013-10-02
US20190040145A1 (en) 2019-02-07
EP2423229A1 (en) 2012-02-29
CN101443360B (zh) 2013-11-27
DK2423229T3 (da) 2013-08-05
SI1999152T1 (sl) 2013-02-28
US20210147559A1 (en) 2021-05-20
SI2423229T1 (sl) 2013-09-30
SI2423230T1 (sl) 2013-09-30
RU2008137763A (ru) 2010-05-10
PT1999152E (pt) 2013-01-07
JP2009533020A (ja) 2009-09-17
PL1999152T3 (pl) 2013-05-31
EP1999152A1 (en) 2008-12-10
RU2495050C2 (ru) 2013-10-10
CN103641916A (zh) 2014-03-19
US9085628B2 (en) 2015-07-21
US20240124596A1 (en) 2024-04-18
EP2423230B1 (en) 2013-05-08
US20190309077A1 (en) 2019-10-10
US20150376285A1 (en) 2015-12-31
KR20130140186A (ko) 2013-12-23
PT2423229E (pt) 2013-08-22
HK1166989A1 (en) 2012-11-16
US8506960B2 (en) 2013-08-13
DK2423230T3 (da) 2013-08-05
JP2013121350A (ja) 2013-06-20
CA2647449C (en) 2017-05-16
MX348827B (es) 2017-06-30
MX2008012291A (es) 2009-01-12
PL2423229T3 (pl) 2013-09-30
JP5665894B2 (ja) 2015-02-04
CN103641915A (zh) 2014-03-19
ES2395839T3 (es) 2013-02-15
US8263075B2 (en) 2012-09-11
RU2639546C2 (ru) 2017-12-21
EP1999152B1 (en) 2012-09-19
US20120141464A1 (en) 2012-06-07
US20140079708A1 (en) 2014-03-20
AU2007231128A1 (en) 2007-10-04
KR101481844B1 (ko) 2015-01-13
EP2423229B1 (en) 2013-05-08
BRPI0709259A2 (pt) 2011-06-28
DK1999152T3 (da) 2013-01-14

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