HK1166790A1 - 季銨鹽化合物 - Google Patents
季銨鹽化合物Info
- Publication number
- HK1166790A1 HK1166790A1 HK12107408.7A HK12107408A HK1166790A1 HK 1166790 A1 HK1166790 A1 HK 1166790A1 HK 12107408 A HK12107408 A HK 12107408A HK 1166790 A1 HK1166790 A1 HK 1166790A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- quaternary ammonium
- ammonium salt
- salt compound
- compound
- quaternary
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/18—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009110760 | 2009-04-30 | ||
| PCT/JP2010/057422 WO2010126025A1 (ja) | 2009-04-30 | 2010-04-27 | 四級アンモニウム塩化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1166790A1 true HK1166790A1 (zh) | 2012-11-09 |
Family
ID=43032170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12107408.7A HK1166790A1 (zh) | 2009-04-30 | 2012-07-27 | 季銨鹽化合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9072734B2 (zh) |
| EP (1) | EP2426121A4 (zh) |
| JP (1) | JP5379224B2 (zh) |
| KR (1) | KR20120061061A (zh) |
| CN (1) | CN102459231B (zh) |
| AR (1) | AR078121A1 (zh) |
| AU (1) | AU2010242646A1 (zh) |
| BR (1) | BRPI1014390A2 (zh) |
| CA (1) | CA2760630A1 (zh) |
| HK (1) | HK1166790A1 (zh) |
| IL (1) | IL216015A0 (zh) |
| MX (1) | MX2011011446A (zh) |
| MY (1) | MY155212A (zh) |
| NZ (1) | NZ595810A (zh) |
| SG (1) | SG177468A1 (zh) |
| TW (1) | TWI486343B (zh) |
| WO (1) | WO2010126025A1 (zh) |
| ZA (1) | ZA201108372B (zh) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2386555A1 (en) | 2010-05-13 | 2011-11-16 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities |
| ITRM20110083U1 (it) | 2010-05-13 | 2011-11-14 | De La Cruz Jose Antonio Freire | Piastra per la costruzione di carrelli per aeroplani |
| CN103562198B (zh) * | 2011-06-10 | 2016-08-24 | 奇斯药制品公司 | 具有毒蕈碱受体拮抗剂和β2肾上腺素能受体激动剂活性的化合物 |
| EP2592078A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
| CA2893626C (en) * | 2012-12-06 | 2021-08-24 | Chiesi Farmaceutici S.P.A. | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| ES2750523T3 (es) | 2012-12-18 | 2020-03-26 | Almirall Sa | Derivados de ciclohexil y quinuclidinil carbamato que tienen actividades de agonista beta2 adrenérgicos y antagonistas muscarínicos M3 |
| TWI643853B (zh) | 2013-02-27 | 2018-12-11 | 阿爾米雷爾有限公司 | 同時具有β2腎上腺素受體促效劑和M3毒蕈鹼受體拮抗劑活性之2-氨基-1-羥乙基-8-羥基喹啉-2(1H)-酮衍生物之鹽類 |
| TW201517906A (zh) | 2013-07-25 | 2015-05-16 | Almirall Sa | 含有ｍａｂａ化合物和皮質類固醇之組合 |
| TWI641373B (zh) | 2013-07-25 | 2018-11-21 | 阿爾米雷爾有限公司 | 具有蕈毒鹼受體拮抗劑和β２腎上腺素受體促效劑二者之活性的２－胺基－１－羥乙基－８－羥基喹啉－２（１Ｈ）－酮衍生物之鹽 |
| US10246407B2 (en) * | 2014-04-25 | 2019-04-02 | Bayer Cropscience Aktiengesellschaft | Process for preparing biphenylamines from anilides by ruthenium catalysis |
| TW201617343A (zh) | 2014-09-26 | 2016-05-16 | 阿爾米雷爾有限公司 | 具有β２腎上腺素促效劑及Ｍ３蕈毒拮抗劑活性之新穎雙環衍生物 |
| CN104557589A (zh) * | 2014-12-24 | 2015-04-29 | 天津大学 | N-(1，1’-二芳基)取代的酰胺类衍生物的制备方法 |
| WO2016180348A1 (zh) * | 2015-05-14 | 2016-11-17 | 四川海思科制药有限公司 | 具有β2受体激动及M受体拮抗活性的含氮杂螺环衍生物及其在医药上的用途 |
| WO2016180349A1 (zh) * | 2015-05-14 | 2016-11-17 | 四川海思科制药有限公司 | 具有β2受体激动及M受体拮抗活性的联苯衍生物及其在医药上的用途 |
| US11447485B2 (en) | 2016-12-14 | 2022-09-20 | Beijing Showby Pharmaceutical Co., Ltd. | Class of bifunctional compounds with quanternary ammonium salt structure |
| CN108854841B (zh) * | 2018-06-25 | 2020-09-29 | 长治学院 | 一种连接基含酯基的吡咯烷类手性Gemini表面活性剂及其制备方法 |
| US11841822B2 (en) | 2019-04-27 | 2023-12-12 | Cambricon Technologies Corporation Limited | Fractal calculating device and method, integrated circuit and board card |
| CN111217746B (zh) * | 2020-03-10 | 2021-09-24 | 佛山市隆信医药科技有限公司 | 一种盐酸丙卡特罗的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3240784A (en) * | 1966-03-15 | Esters of quaternary z-hydroxy methyl piperidinium compounds | ||
| TWI249515B (en) * | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
| AU2003249294A1 (en) | 2002-07-17 | 2004-02-02 | Long Y. Chiang | Fullerene compounds |
| PE20040950A1 (es) * | 2003-02-14 | 2005-01-01 | Theravance Inc | DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS |
| CN101239970B (zh) * | 2003-02-14 | 2011-07-20 | 施万制药 | 联苯衍生物 |
| WO2004089892A2 (en) | 2003-04-01 | 2004-10-21 | Theravance, Inc. | Diarylmethyl and related compounds having beta2 andrenergic receptor agonist and muscarinic receptor antagonist activity |
| CA2523246C (en) | 2003-04-25 | 2009-12-01 | Kos Life Sciences, Inc. | Formation of strong superporous hydrogels |
| ATE435862T1 (de) | 2003-05-28 | 2009-07-15 | Theravance Inc | Azabicycloalkanverbindungen als muscarinrezeptor antagonisten |
| TWI378092B (en) * | 2003-06-03 | 2012-12-01 | Rib X Pharmaceuticals Inc | Biaryl heterocyclic compounds and methods of making and using the same |
| PE20050231A1 (es) * | 2003-06-24 | 2005-05-20 | Novartis Ag | Derivados de piperidinium y pirrolidinium como antagonistas del receptor muscarinico m3 |
| TW200534855A (en) * | 2004-01-13 | 2005-11-01 | Glaxo Group Ltd | Muscarinic acetylcholine receptor antagonists |
| CA2643097C (en) | 2006-03-20 | 2012-03-13 | Pfizer Limited | Amine derivatives |
| GB0702413D0 (en) | 2007-02-07 | 2007-03-21 | Argenta Discovery Ltd | New chemical compounds |
| JP4934223B2 (ja) | 2008-02-06 | 2012-05-16 | アストラゼネカ・アクチエボラーグ | 化合物 |
-
2010
- 2010-04-27 NZ NZ595810A patent/NZ595810A/xx not_active IP Right Cessation
- 2010-04-27 MY MYPI2011005166A patent/MY155212A/en unknown
- 2010-04-27 BR BRPI1014390A patent/BRPI1014390A2/pt not_active IP Right Cessation
- 2010-04-27 CN CN201080029330.3A patent/CN102459231B/zh not_active Expired - Fee Related
- 2010-04-27 KR KR1020117028059A patent/KR20120061061A/ko not_active Application Discontinuation
- 2010-04-27 SG SG2011097920A patent/SG177468A1/en unknown
- 2010-04-27 WO PCT/JP2010/057422 patent/WO2010126025A1/ja active Application Filing
- 2010-04-27 AU AU2010242646A patent/AU2010242646A1/en not_active Abandoned
- 2010-04-27 EP EP10769723A patent/EP2426121A4/en not_active Withdrawn
- 2010-04-27 JP JP2011511402A patent/JP5379224B2/ja not_active Expired - Fee Related
- 2010-04-27 CA CA2760630A patent/CA2760630A1/en active Pending
- 2010-04-27 US US13/266,651 patent/US9072734B2/en not_active Expired - Fee Related
- 2010-04-27 MX MX2011011446A patent/MX2011011446A/es active IP Right Grant
- 2010-04-29 AR ARP100101446A patent/AR078121A1/es unknown
- 2010-04-30 TW TW099113895A patent/TWI486343B/zh not_active IP Right Cessation
-
2011
- 2011-10-27 IL IL216015A patent/IL216015A0/en unknown
- 2011-11-15 ZA ZA2011/08372A patent/ZA201108372B/en unknown
-
2012
- 2012-07-27 HK HK12107408.7A patent/HK1166790A1/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SG177468A1 (en) | 2012-02-28 |
| JP5379224B2 (ja) | 2013-12-25 |
| EP2426121A4 (en) | 2012-10-31 |
| JPWO2010126025A1 (ja) | 2012-11-01 |
| US9072734B2 (en) | 2015-07-07 |
| US20120046467A1 (en) | 2012-02-23 |
| AU2010242646A1 (en) | 2011-11-03 |
| KR20120061061A (ko) | 2012-06-12 |
| WO2010126025A1 (ja) | 2010-11-04 |
| CN102459231B (zh) | 2015-04-22 |
| MY155212A (en) | 2015-09-30 |
| AR078121A1 (es) | 2011-10-19 |
| TW201103909A (en) | 2011-02-01 |
| CA2760630A1 (en) | 2010-11-04 |
| IL216015A0 (en) | 2012-01-31 |
| NZ595810A (en) | 2013-05-31 |
| ZA201108372B (en) | 2012-07-25 |
| TWI486343B (zh) | 2015-06-01 |
| CN102459231A (zh) | 2012-05-16 |
| EP2426121A1 (en) | 2012-03-07 |
| MX2011011446A (es) | 2011-11-18 |
| BRPI1014390A2 (pt) | 2016-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190501 |