HK1144192A1 - Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester (r)-3--345- 1-[222] - Google Patents

Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester (r)-3--345- 1-[222]

Info

Publication number
HK1144192A1
HK1144192A1 HK10110355.6A HK10110355A HK1144192A1 HK 1144192 A1 HK1144192 A1 HK 1144192A1 HK 10110355 A HK10110355 A HK 10110355A HK 1144192 A1 HK1144192 A1 HK 1144192A1
Authority
HK
Hong Kong
Prior art keywords
azabiciyclo
fluorophenyl
oct
ester
crystalline salt
Prior art date
Application number
HK10110355.6A
Other languages
English (en)
Chinese (zh)
Inventor
Ruiz Juan Lorenzo Catena
Rodriguez Jos Hidalgo
Comas Maria Del Carmen Serra
Masip Isabel Masip
Original Assignee
Salvat Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salvat Lab Sa filed Critical Salvat Lab Sa
Publication of HK1144192A1 publication Critical patent/HK1144192A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK10110355.6A 2007-11-28 2010-11-04 Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester (r)-3--345- 1-[222] HK1144192A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07384038A EP2065385A1 (en) 2007-11-28 2007-11-28 Stable crystalline salt of (R)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester
PCT/EP2008/010012 WO2009068253A2 (en) 2007-11-28 2008-11-26 Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabicyclo [2.2.2]oct-yl ester

Publications (1)

Publication Number Publication Date
HK1144192A1 true HK1144192A1 (en) 2011-02-02

Family

ID=39401152

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10110355.6A HK1144192A1 (en) 2007-11-28 2010-11-04 Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester (r)-3--345- 1-[222]

Country Status (19)

Country Link
US (2) US8492402B2 (xx)
EP (2) EP2065385A1 (xx)
JP (1) JP5336509B2 (xx)
KR (1) KR101557832B1 (xx)
CN (1) CN101925600B (xx)
AU (1) AU2008329181B2 (xx)
BR (1) BRPI0819607A2 (xx)
CA (1) CA2706565C (xx)
DK (1) DK2220082T3 (xx)
EA (1) EA017483B1 (xx)
ES (1) ES2498819T3 (xx)
HK (1) HK1144192A1 (xx)
IL (1) IL206032A (xx)
MX (1) MX2010005850A (xx)
NZ (1) NZ585833A (xx)
PL (1) PL2220082T3 (xx)
UA (1) UA102083C2 (xx)
WO (1) WO2009068253A2 (xx)
ZA (1) ZA201003718B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002051841A1 (en) 2000-12-22 2002-07-04 Almirall Prodesfarma Ag Quinuclidine carbamate derivatives and their use as m3 antagonists
KR102108226B1 (ko) † 2010-02-12 2020-05-08 화이자 인코포레이티드 8-플루오로-2-｛4-［(메틸아미노)메틸］페닐｝-1,3,4,5-테트라하이드로-6ｈ-아제피노［5,4,3-ｃｄ］인돌-6-온의 염 및 다형체
KR101978364B1 (ko) 2017-06-15 2019-05-14 크리스탈지노믹스(주) 알킬카바모일 나프탈렌일옥시 옥테노일 하이드록시아마이드 또는 그 유도체의 약학적으로 허용 가능한 염 및 그 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE510305C2 (sv) * 1997-05-30 1999-05-10 Astra Ab Nytt salt
DK1300407T4 (da) 2000-06-27 2011-09-05 S A L V A T Lab Sa Carbamater afledt af arylalkylaminer
WO2002051841A1 (en) * 2000-12-22 2002-07-04 Almirall Prodesfarma Ag Quinuclidine carbamate derivatives and their use as m3 antagonists
WO2003053966A2 (en) 2001-12-20 2003-07-03 Laboratorios S.A.L.V.A.T., S.A. 1-alkyl-1-azoniabicyclo [2.2.2] octane carbamate derivatives and their use as muscarinic receptor antagonists
ES2203327B1 (es) * 2002-06-21 2005-06-16 Almirall Prodesfarma, S.A. Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.
ES2246170B1 (es) * 2004-07-29 2007-04-01 Almirall Prodesfarma, S.A. Nuevo procedimiento para preparar derivados de carbamato de quinuclidinio.

Also Published As

Publication number Publication date
EA017483B1 (ru) 2012-12-28
WO2009068253A2 (en) 2009-06-04
AU2008329181A1 (en) 2009-06-04
IL206032A (en) 2014-07-31
MX2010005850A (es) 2010-09-03
US20140051721A1 (en) 2014-02-20
EA201070651A1 (ru) 2010-12-30
ZA201003718B (en) 2011-08-31
EP2065385A1 (en) 2009-06-03
DK2220082T3 (da) 2014-10-06
PL2220082T3 (pl) 2014-12-31
NZ585833A (en) 2011-05-27
UA102083C2 (xx) 2013-06-10
JP2011504890A (ja) 2011-02-17
US20110207769A1 (en) 2011-08-25
EP2220082A2 (en) 2010-08-25
JP5336509B2 (ja) 2013-11-06
ES2498819T3 (es) 2014-09-25
US8871787B2 (en) 2014-10-28
KR20100103532A (ko) 2010-09-27
KR101557832B1 (ko) 2015-10-06
IL206032A0 (en) 2010-11-30
WO2009068253A3 (en) 2009-08-13
CN101925600B (zh) 2013-01-09
BRPI0819607A2 (pt) 2015-10-13
CA2706565A1 (en) 2009-06-04
CA2706565C (en) 2015-04-28
US8492402B2 (en) 2013-07-23
AU2008329181B2 (en) 2012-03-29
EP2220082B1 (en) 2014-06-25
CN101925600A (zh) 2010-12-22

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20171126