MX2010005850A - Sal cristalina estable de ester 1-azabiciclo[2.2.2]oct-3-ilico del acido (r)-3-fluorofenil-3,4,5-trifluorobencilcarbamico. - Google Patents

Sal cristalina estable de ester 1-azabiciclo[2.2.2]oct-3-ilico del acido (r)-3-fluorofenil-3,4,5-trifluorobencilcarbamico.

Info

Publication number
MX2010005850A
MX2010005850A MX2010005850A MX2010005850A MX2010005850A MX 2010005850 A MX2010005850 A MX 2010005850A MX 2010005850 A MX2010005850 A MX 2010005850A MX 2010005850 A MX2010005850 A MX 2010005850A MX 2010005850 A MX2010005850 A MX 2010005850A
Authority
MX
Mexico
Prior art keywords
azabicyclo
fluorophenyl
oct
ester
trifluorobenz
Prior art date
Application number
MX2010005850A
Other languages
English (en)
Inventor
Jose Hidalgo Rodriguez
Isabel Masip Masip
Juan Lorenzo Catena Ruiz
Maria Del Carmen Serra Comas
Original Assignee
Salvat Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salvat Lab Sa filed Critical Salvat Lab Sa
Publication of MX2010005850A publication Critical patent/MX2010005850A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a una sal cristalina estable de éster 1-azabiciclo[2.2.2]oct-3-ílico del ácido (R)-3-fluorofenil-3, 4, 5-trifluorobencilcarbámico y su uso como medicamento, en particular para el tratamiento de incontinencia urinaria u otras enfermedades que implican trastornos genitourinarios.
MX2010005850A 2007-11-28 2008-11-26 Sal cristalina estable de ester 1-azabiciclo[2.2.2]oct-3-ilico del acido (r)-3-fluorofenil-3,4,5-trifluorobencilcarbamico. MX2010005850A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07384038A EP2065385A1 (en) 2007-11-28 2007-11-28 Stable crystalline salt of (R)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester
PCT/EP2008/010012 WO2009068253A2 (en) 2007-11-28 2008-11-26 Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabicyclo [2.2.2]oct-yl ester

Publications (1)

Publication Number Publication Date
MX2010005850A true MX2010005850A (es) 2010-09-03

Family

ID=39401152

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005850A MX2010005850A (es) 2007-11-28 2008-11-26 Sal cristalina estable de ester 1-azabiciclo[2.2.2]oct-3-ilico del acido (r)-3-fluorofenil-3,4,5-trifluorobencilcarbamico.

Country Status (19)

Country Link
US (2) US8492402B2 (es)
EP (2) EP2065385A1 (es)
JP (1) JP5336509B2 (es)
KR (1) KR101557832B1 (es)
CN (1) CN101925600B (es)
AU (1) AU2008329181B2 (es)
BR (1) BRPI0819607A2 (es)
CA (1) CA2706565C (es)
DK (1) DK2220082T3 (es)
EA (1) EA017483B1 (es)
ES (1) ES2498819T3 (es)
HK (1) HK1144192A1 (es)
IL (1) IL206032A (es)
MX (1) MX2010005850A (es)
NZ (1) NZ585833A (es)
PL (1) PL2220082T3 (es)
UA (1) UA102083C2 (es)
WO (1) WO2009068253A2 (es)
ZA (1) ZA201003718B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100869722B1 (ko) 2000-12-22 2008-11-21 알미랄 에이쥐 퀴누클리딘 카르바메이트 유도체 및 ｍ3 길항제로서 그의사용
CN104876937B (zh) † 2010-02-12 2017-07-28 辉瑞公司 8‑氟‑2‑{4‑[(甲氨基)甲基]苯基}‑1,3,4,5‑四氢‑6H‑氮杂*并[5,4,3‑cd]吲哚‑6‑酮的马来酸盐、其药物组合物及其用途
KR101978364B1 (ko) * 2017-06-15 2019-05-14 크리스탈지노믹스(주) 알킬카바모일 나프탈렌일옥시 옥테노일 하이드록시아마이드 또는 그 유도체의 약학적으로 허용 가능한 염 및 그 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE510305C2 (sv) * 1997-05-30 1999-05-10 Astra Ab Nytt salt
HU229306B1 (en) 2000-06-27 2013-10-28 L V A T Lab Sa Carbamates derived from arylalkylamines
KR100869722B1 (ko) * 2000-12-22 2008-11-21 알미랄 에이쥐 퀴누클리딘 카르바메이트 유도체 및 ｍ3 길항제로서 그의사용
EP1461336B1 (en) * 2001-12-20 2013-05-22 CHIESI FARMACEUTICI S.p.A. 1-alkyl-1-azoniabicyclo (2.2.2) octane carbamate derivatives and their use as muscarinic receptor antagonists
ES2203327B1 (es) 2002-06-21 2005-06-16 Almirall Prodesfarma, S.A. Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.
ES2246170B1 (es) * 2004-07-29 2007-04-01 Almirall Prodesfarma, S.A. Nuevo procedimiento para preparar derivados de carbamato de quinuclidinio.

Also Published As

Publication number Publication date
WO2009068253A3 (en) 2009-08-13
CA2706565A1 (en) 2009-06-04
US8492402B2 (en) 2013-07-23
AU2008329181B2 (en) 2012-03-29
JP2011504890A (ja) 2011-02-17
KR101557832B1 (ko) 2015-10-06
IL206032A (en) 2014-07-31
WO2009068253A2 (en) 2009-06-04
BRPI0819607A2 (pt) 2015-10-13
US20140051721A1 (en) 2014-02-20
EP2220082A2 (en) 2010-08-25
IL206032A0 (en) 2010-11-30
EP2220082B1 (en) 2014-06-25
AU2008329181A1 (en) 2009-06-04
KR20100103532A (ko) 2010-09-27
CN101925600A (zh) 2010-12-22
EA017483B1 (ru) 2012-12-28
ES2498819T3 (es) 2014-09-25
EA201070651A1 (ru) 2010-12-30
UA102083C2 (uk) 2013-06-10
NZ585833A (en) 2011-05-27
HK1144192A1 (en) 2011-02-02
JP5336509B2 (ja) 2013-11-06
CA2706565C (en) 2015-04-28
ZA201003718B (en) 2011-08-31
US8871787B2 (en) 2014-10-28
CN101925600B (zh) 2013-01-09
PL2220082T3 (pl) 2014-12-31
DK2220082T3 (da) 2014-10-06
US20110207769A1 (en) 2011-08-25
EP2065385A1 (en) 2009-06-03

Similar Documents

Publication Publication Date Title
WO2010141796A3 (en) PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a] PYRIDINE DERIVATIVES
ZA200810113B (en) Method for the treatment and prevention of ocular disorders
WO2008115974A3 (en) Pyrazolopyrimidine analogs and their use as mtor kinase and pi3 kinase inhibitors
AU2007257423A8 (en) Purine analogs
WO2011058474A8 (en) N1-pyrazolospiroketone acetyl-coa carboxylase inhibitors
WO2008116129A3 (en) Imidazolopyrimidine analogs and their use as pi3 kinase and mtor inhibitors
WO2012016186A8 (en) Macrocyclic kinase inhibitors and uses thereof
WO2010091067A3 (en) Derivatives of [1, 3] oxazin- 2-one useful for the treatment of metabolic diseases such as lipid disorders
WO2009127669A3 (en) Ido inhibitors and therapeutic uses thereof
AU2016219650A1 (en) Compositions and methods for extended therapy with aminopyridines
NZ600874A (en) Fluorinated derivatives of deferiprone
GEP20146100B (en) Novel phenylimidazole derivative as pde10a enzyme inhibitor
WO2008137816A8 (en) Tricyclic compounds as matrix metalloproteinase inhibitors
WO2008052139A3 (en) Ultra low dose doxepin and methods of using the same to treat sleep disorders
WO2010107807A3 (en) Compounds for treating inflammation and pain
WO2007136741A3 (en) N-desmethyl-doxepin and methods of using the same to treat sleep disorders
MX366496B (es) Metodos para preparar composiciones farmaceuticas que comprenden acetato de eslicarbazepina y metodos de uso.
MY173491A (en) Therapeutic or prophylactic agent for biliary tract diseases
SG141358A1 (en) Treatment of psychiatric patients with reduced heptaic function with paliperidone
MX2010010345A (es) Composiciones oftalmicas topicas mejoradas.
MX2010005850A (es) Sal cristalina estable de ester 1-azabiciclo[2.2.2]oct-3-ilico del acido (r)-3-fluorofenil-3,4,5-trifluorobencilcarbamico.
GEP20125570B (en) Use of indazolemethoxyalkanoic acid for reducing levels of triglycerides, cholesterol and glucose
TW200833708A (en) Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
WO2014047288A3 (en) Transglutaminase tg2 inhibitors, pharmaceutical compositions, and methods of use thereof
MX2010003615A (es) Tratamiento de desordenes neurologicos.

Legal Events

Date Code Title Description
FG Grant or registration