HK1143361A1 - Novel method for the synthesis of anticancer (poly)aminoalkylaminoacetamide derivatives of epipodophyllotoxin - Google Patents

Novel method for the synthesis of anticancer (poly)aminoalkylaminoacetamide derivatives of epipodophyllotoxin

Info

Publication number
HK1143361A1
HK1143361A1 HK10109818.9A HK10109818A HK1143361A1 HK 1143361 A1 HK1143361 A1 HK 1143361A1 HK 10109818 A HK10109818 A HK 10109818A HK 1143361 A1 HK1143361 A1 HK 1143361A1
Authority
HK
Hong Kong
Prior art keywords
epipodophyllotoxin
anticancer
poly
synthesis
novel method
Prior art date
Application number
HK10109818.9A
Other languages
English (en)
Inventor
Yves Guminski
Martial Grousseaud
Thierry Imbert
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of HK1143361A1 publication Critical patent/HK1143361A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK10109818.9A 2007-09-25 2010-10-18 Novel method for the synthesis of anticancer (poly)aminoalkylaminoacetamide derivatives of epipodophyllotoxin HK1143361A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0706692A FR2921368B1 (fr) 2007-09-25 2007-09-25 Nouveau procede de synthese de derives anticancereux de (poly) aminoalkylaminoacetamide d'epipodophyllotoxine.
PCT/FR2008/051697 WO2009050363A1 (fr) 2007-09-25 2008-09-23 Procede de synthese de derives anticancereux de ( poly) aminoalkylaminoacetamide d ' epipodophyllotoxine

Publications (1)

Publication Number Publication Date
HK1143361A1 true HK1143361A1 (en) 2010-12-31

Family

ID=39322470

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10109818.9A HK1143361A1 (en) 2007-09-25 2010-10-18 Novel method for the synthesis of anticancer (poly)aminoalkylaminoacetamide derivatives of epipodophyllotoxin

Country Status (19)

Country Link
US (1) US8148552B2 (es)
EP (1) EP2203455B1 (es)
JP (1) JP5420549B2 (es)
KR (1) KR101336921B1 (es)
CN (1) CN101809022B (es)
AU (1) AU2008313616B2 (es)
BR (1) BRPI0817326A2 (es)
CA (1) CA2700161C (es)
FR (1) FR2921368B1 (es)
HK (1) HK1143361A1 (es)
IL (1) IL204636A (es)
MA (1) MA31689B1 (es)
MX (1) MX2010001556A (es)
MY (1) MY146171A (es)
NZ (1) NZ583814A (es)
RU (1) RU2450009C2 (es)
TN (1) TN2010000095A1 (es)
WO (1) WO2009050363A1 (es)
ZA (1) ZA201001265B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2624903C1 (ru) * 2016-11-02 2017-07-10 федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) Производные ванилина с противоопухолевой активностью

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5066737A (en) 1990-10-22 1991-11-19 Shell Oil Company Olefin polymerization catalyst
SU598871A1 (ru) 1976-07-26 1978-03-25 Всесоюзный научно-исследовательский институт технологии кровезаменителей и гормональных препаратов Способ получени гидрохлорида метиламиноацетопирокатехина
US4612299A (en) 1984-07-09 1986-09-16 Amoco Corporation Magnesium carboxylate supports
US5567665A (en) 1994-03-31 1996-10-22 Union Carbide Chemicals & Plastics Technology Corporation Shape-shifted magnesium alkoxide component for polymerizing olefins
US4579836A (en) 1985-05-22 1986-04-01 Amoco Corporation Exhaustively prepolymerized supported alpha-olefin polymerization catalyst
CN1068330A (zh) * 1991-07-03 1993-01-27 国家医药管理局上海医药工业研究院 4-氮取代-4-脱氧-4′-去甲表鬼臼毒素衍生物及其合成方法
US6051666A (en) 1995-04-10 2000-04-18 Dsm N.V. Method for preparing a catalyst suitable for polymerizing an olefin
FR2742439B1 (fr) * 1995-12-14 1998-03-06 Pf Medicament Procede de preparation de la 4'-demethylepipodophyllotoxine a partir de la podophyllotoxine
AU6952698A (en) 1997-04-07 1998-10-30 Mallinckrodt Chemical, Inc. Modification of polymer molecular weight distribution by using mixed silane systems in high activity polymerization catalysts
ID28200A (id) 1999-04-15 2001-05-10 Basell Technology Co Bv Komponen katalis untuk polimerisasi olefin
MXPA03001149A (es) 2001-06-07 2003-06-09 Basell Poliolefine Spa Procedimiento para la preparacion de esteres del acido succinico sustituidos con alquilideno.
EP1336625A1 (en) 2002-02-14 2003-08-20 Novolen Technology Holdings C.V. Solid catalytic component and catalytic system of the Ziegler-Natta type, process for their preparation and their use in the polymerisation of alk-1-enes
WO2004073375A2 (en) * 2003-02-18 2004-09-02 Ranbaxy Laboratories Limited Podophyllotoxin derivatives as antitumor agents
FR2869035B1 (fr) * 2004-04-16 2006-07-14 Pierre Fabre Medicament Sa Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux
FR2888849B1 (fr) * 2005-07-19 2007-10-05 Pierre Fabre Medicament Sa Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine

Also Published As

Publication number Publication date
WO2009050363A1 (fr) 2009-04-23
KR20100058536A (ko) 2010-06-03
MX2010001556A (es) 2010-03-15
NZ583814A (en) 2012-01-12
EP2203455B1 (fr) 2017-08-30
IL204636A (en) 2013-11-28
AU2008313616B2 (en) 2012-01-19
EP2203455A1 (fr) 2010-07-07
US8148552B2 (en) 2012-04-03
CN101809022A (zh) 2010-08-18
BRPI0817326A2 (pt) 2015-03-24
US20100280263A1 (en) 2010-11-04
ZA201001265B (en) 2010-11-24
FR2921368B1 (fr) 2012-10-12
CA2700161C (fr) 2013-11-19
MA31689B1 (fr) 2010-09-01
JP2010540505A (ja) 2010-12-24
AU2008313616A1 (en) 2009-04-23
RU2450009C2 (ru) 2012-05-10
FR2921368A1 (fr) 2009-03-27
RU2010116166A (ru) 2011-11-10
CN101809022B (zh) 2012-07-04
TN2010000095A1 (fr) 2011-09-26
CA2700161A1 (fr) 2009-04-23
JP5420549B2 (ja) 2014-02-19
KR101336921B1 (ko) 2013-12-04
MY146171A (en) 2012-07-13
IL204636A0 (en) 2010-11-30

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HK1143361A1 (en) Novel method for the synthesis of anticancer (poly)aminoalkylaminoacetamide derivatives of epipodophyllotoxin

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20200919