HK1140698A1 - 用於治療血管成形術或動脈內膜切除術後的再狹窄和由器官纖維化導致的疾病的 β， β-雄甾烷衍生物 - Google Patents
用於治療血管成形術或動脈內膜切除術後的再狹窄和由器官纖維化導致的疾病的 β， β-雄甾烷衍生物Info
- Publication number
- HK1140698A1 HK1140698A1 HK10107264.2A HK10107264A HK1140698A1 HK 1140698 A1 HK1140698 A1 HK 1140698A1 HK 10107264 A HK10107264 A HK 10107264A HK 1140698 A1 HK1140698 A1 HK 1140698A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- endoartherectomy
- 14beta
- angioplastic
- restenosis
- beta
- Prior art date
Links
- QZLYKIGBANMMBK-CCZRDMDKSA-N (8s,9s,10s,13s,14r)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthrene Chemical class C1CC2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@H]1CCC[C@@]1(C)CC2 QZLYKIGBANMMBK-CCZRDMDKSA-N 0.000 title 1
- 206010016654 Fibrosis Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000004761 fibrosis Effects 0.000 title 1
- 210000000056 organ Anatomy 0.000 title 1
- 208000037803 restenosis Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07109779 | 2007-06-07 | ||
| PCT/EP2008/056928 WO2008148812A1 (en) | 2007-06-07 | 2008-06-04 | 5beta, 14beta-androstane derivatives useful for the treatment of restenosis after angioplastic or endoartherectomy and diseases due to organ fibrosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1140698A1 true HK1140698A1 (zh) | 2010-10-22 |
Family
ID=38662675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK10107264.2A HK1140698A1 (zh) | 2007-06-07 | 2010-07-29 | 用於治療血管成形術或動脈內膜切除術後的再狹窄和由器官纖維化導致的疾病的 β， β-雄甾烷衍生物 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20100303896A1 (zh) |
| EP (1) | EP2160190B1 (zh) |
| JP (1) | JP5579058B2 (zh) |
| KR (1) | KR101530019B1 (zh) |
| CN (1) | CN101720224B (zh) |
| AU (1) | AU2008258521B2 (zh) |
| BR (1) | BRPI0812775B8 (zh) |
| CA (1) | CA2688079C (zh) |
| DK (1) | DK2160190T3 (zh) |
| ES (1) | ES2556731T3 (zh) |
| HK (1) | HK1140698A1 (zh) |
| HR (1) | HRP20151233T1 (zh) |
| HU (1) | HUE025599T2 (zh) |
| MX (1) | MX2009012917A (zh) |
| PL (1) | PL2160190T3 (zh) |
| PT (1) | PT2160190E (zh) |
| RS (1) | RS54459B1 (zh) |
| SI (1) | SI2160190T1 (zh) |
| WO (1) | WO2008148812A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010227644B2 (en) * | 2009-03-23 | 2016-05-19 | Cvie Therapeutics Limited | 5-beta, 14-beta-androstane derivatives useful for the treatment of proteinuria, glomerulosclerosis and renal failure |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW226375B (zh) * | 1991-10-24 | 1994-07-11 | American Home Prod | |
| EP0625902A1 (en) * | 1992-02-14 | 1994-11-30 | Warner-Lambert Company | Method of treating abnormal tissue proliferation by administering an angiotensin ii antagonist |
| DE4227616C2 (de) * | 1992-08-20 | 1995-04-13 | Sigma Tau Ind Farmaceuti | 17-(3-Furyl)-und 17-(4-Pyridazinyl)-5beta, 14beta-androstanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammemsetzungen |
| DE4232638C2 (de) * | 1992-09-29 | 1994-11-17 | Sigma Tau Ind Farmaceuti | 17-Phenyl-5beta-14beta-androstanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen |
| ES2126061T3 (es) * | 1993-03-24 | 1999-03-16 | American Home Prod | Piridopirimidinas substituidas como antihipertensores. |
| WO2004089416A2 (en) * | 2003-04-11 | 2004-10-21 | Novo Nordisk A/S | Combination of an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and an antihypertensive agent |
| EP1812010A2 (en) * | 2004-10-18 | 2007-08-01 | BTG International Limited | Use of na+/ k+-atpase inhibitors and antagonists thereof |
-
2008
- 2008-06-04 RS RS20150845A patent/RS54459B1/en unknown
- 2008-06-04 WO PCT/EP2008/056928 patent/WO2008148812A1/en active Application Filing
- 2008-06-04 HU HUE08760508A patent/HUE025599T2/en unknown
- 2008-06-04 KR KR1020097024493A patent/KR101530019B1/ko active IP Right Grant
- 2008-06-04 DK DK08760508.5T patent/DK2160190T3/en active
- 2008-06-04 ES ES08760508.5T patent/ES2556731T3/es active Active
- 2008-06-04 US US12/602,827 patent/US20100303896A1/en not_active Abandoned
- 2008-06-04 AU AU2008258521A patent/AU2008258521B2/en not_active Ceased
- 2008-06-04 SI SI200831539T patent/SI2160190T1/sl unknown
- 2008-06-04 JP JP2010510789A patent/JP5579058B2/ja not_active Expired - Fee Related
- 2008-06-04 EP EP08760508.5A patent/EP2160190B1/en active Active
- 2008-06-04 BR BRPI0812775A patent/BRPI0812775B8/pt not_active IP Right Cessation
- 2008-06-04 CA CA2688079A patent/CA2688079C/en active Active
- 2008-06-04 MX MX2009012917A patent/MX2009012917A/es active IP Right Grant
- 2008-06-04 PL PL08760508T patent/PL2160190T3/pl unknown
- 2008-06-04 PT PT87605085T patent/PT2160190E/pt unknown
- 2008-06-04 CN CN200880019175.XA patent/CN101720224B/zh active Active
-
2010
- 2010-07-29 HK HK10107264.2A patent/HK1140698A1/zh not_active IP Right Cessation
-
2015
- 2015-11-16 HR HRP20151233TT patent/HRP20151233T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2688079C (en) | 2016-05-03 |
| WO2008148812A1 (en) | 2008-12-11 |
| RS54459B1 (en) | 2016-06-30 |
| KR20100022021A (ko) | 2010-02-26 |
| BRPI0812775A2 (pt) | 2014-12-02 |
| CA2688079A1 (en) | 2008-12-11 |
| AU2008258521A1 (en) | 2008-12-11 |
| JP2010529082A (ja) | 2010-08-26 |
| EP2160190A1 (en) | 2010-03-10 |
| KR101530019B1 (ko) | 2015-06-18 |
| BRPI0812775B1 (pt) | 2020-02-04 |
| CN101720224B (zh) | 2014-03-26 |
| PL2160190T3 (pl) | 2016-03-31 |
| JP5579058B2 (ja) | 2014-08-27 |
| DK2160190T3 (en) | 2016-01-11 |
| ES2556731T3 (es) | 2016-01-19 |
| CN101720224A (zh) | 2010-06-02 |
| PT2160190E (pt) | 2016-01-27 |
| MX2009012917A (es) | 2010-01-14 |
| AU2008258521B2 (en) | 2013-03-28 |
| US20100303896A1 (en) | 2010-12-02 |
| HRP20151233T1 (hr) | 2015-12-18 |
| HUE025599T2 (en) | 2016-05-30 |
| EP2160190B1 (en) | 2015-11-04 |
| SI2160190T1 (sl) | 2015-12-31 |
| BRPI0812775B8 (pt) | 2021-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230604 |