SI2160190T1 - Derivati 5 beta, 14 beta-androstana, uporabni za zdravljenje bolezni zaradi fibroze organov - Google Patents

Derivati 5 beta, 14 beta-androstana, uporabni za zdravljenje bolezni zaradi fibroze organov

Info

Publication number
SI2160190T1
SI2160190T1 SI200831539T SI200831539T SI2160190T1 SI 2160190 T1 SI2160190 T1 SI 2160190T1 SI 200831539 T SI200831539 T SI 200831539T SI 200831539 T SI200831539 T SI 200831539T SI 2160190 T1 SI2160190 T1 SI 2160190T1
Authority
SI
Slovenia
Prior art keywords
14beta
5beta
treatment
derivatives useful
diseases due
Prior art date
Application number
SI200831539T
Other languages
English (en)
Inventor
Liberato Berrino
Antonio Cascino
Marilena Cipollaro
Amalia Forte
Francesco Rossi
Giuseppe Bianchi
Patrizia Ferrari
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of SI2160190T1 publication Critical patent/SI2160190T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI200831539T 2007-06-07 2008-06-04 Derivati 5 beta, 14 beta-androstana, uporabni za zdravljenje bolezni zaradi fibroze organov SI2160190T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07109779 2007-06-07
PCT/EP2008/056928 WO2008148812A1 (en) 2007-06-07 2008-06-04 5beta, 14beta-androstane derivatives useful for the treatment of restenosis after angioplastic or endoartherectomy and diseases due to organ fibrosis
EP08760508.5A EP2160190B1 (en) 2007-06-07 2008-06-04 5beta, 14beta-androstane derivatives useful for the treatment of diseases due to organ fibrosis

Publications (1)

Publication Number Publication Date
SI2160190T1 true SI2160190T1 (sl) 2015-12-31

Family

ID=38662675

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200831539T SI2160190T1 (sl) 2007-06-07 2008-06-04 Derivati 5 beta, 14 beta-androstana, uporabni za zdravljenje bolezni zaradi fibroze organov

Country Status (19)

Country Link
US (1) US20100303896A1 (sl)
EP (1) EP2160190B1 (sl)
JP (1) JP5579058B2 (sl)
KR (1) KR101530019B1 (sl)
CN (1) CN101720224B (sl)
AU (1) AU2008258521B2 (sl)
BR (1) BRPI0812775B8 (sl)
CA (1) CA2688079C (sl)
DK (1) DK2160190T3 (sl)
ES (1) ES2556731T3 (sl)
HK (1) HK1140698A1 (sl)
HR (1) HRP20151233T1 (sl)
HU (1) HUE025599T2 (sl)
MX (1) MX2009012917A (sl)
PL (1) PL2160190T3 (sl)
PT (1) PT2160190E (sl)
RS (1) RS54459B1 (sl)
SI (1) SI2160190T1 (sl)
WO (1) WO2008148812A1 (sl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI1012240A2 (pt) * 2009-03-23 2018-06-12 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. derivados de 5-beta, beta-14-androstana úteis para o tratamento de proteinúria, de glomeruloesclerose e de insuficiência renal

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW226375B (sl) * 1991-10-24 1994-07-11 American Home Prod
EP0625902A1 (en) * 1992-02-14 1994-11-30 Warner-Lambert Company Method of treating abnormal tissue proliferation by administering an angiotensin ii antagonist
DE4227616C2 (de) * 1992-08-20 1995-04-13 Sigma Tau Ind Farmaceuti 17-(3-Furyl)-und 17-(4-Pyridazinyl)-5beta, 14beta-androstanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammemsetzungen
DE4232638C2 (de) * 1992-09-29 1994-11-17 Sigma Tau Ind Farmaceuti 17-Phenyl-5beta-14beta-androstanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
EP0618207B1 (en) * 1993-03-24 1999-01-07 American Home Products Corporation Substituted pyridopyrimidines as antihypertensives
JP2006522750A (ja) * 2003-04-11 2006-10-05 ノボ ノルディスク アクティーゼルスカブ 代謝性症候群ならびに関連の疾患および障害を治療するために、11β−ヒドロキシステロイドデヒドロゲナーゼ1型阻害剤および抗高血圧剤を使用する併用療法
US20060135443A1 (en) 2004-10-18 2006-06-22 Bionaut Pharmaceuticals, Inc. Use of Na*/K*-ATPase inhibitors and antagonists thereof

Also Published As

Publication number Publication date
CA2688079A1 (en) 2008-12-11
ES2556731T3 (es) 2016-01-19
BRPI0812775A2 (pt) 2014-12-02
AU2008258521B2 (en) 2013-03-28
US20100303896A1 (en) 2010-12-02
BRPI0812775B1 (pt) 2020-02-04
MX2009012917A (es) 2010-01-14
PT2160190E (pt) 2016-01-27
HRP20151233T1 (hr) 2015-12-18
KR101530019B1 (ko) 2015-06-18
CN101720224B (zh) 2014-03-26
DK2160190T3 (en) 2016-01-11
PL2160190T3 (pl) 2016-03-31
RS54459B1 (en) 2016-06-30
CN101720224A (zh) 2010-06-02
CA2688079C (en) 2016-05-03
JP5579058B2 (ja) 2014-08-27
WO2008148812A1 (en) 2008-12-11
AU2008258521A1 (en) 2008-12-11
HK1140698A1 (en) 2010-10-22
EP2160190A1 (en) 2010-03-10
KR20100022021A (ko) 2010-02-26
HUE025599T2 (en) 2016-05-30
EP2160190B1 (en) 2015-11-04
JP2010529082A (ja) 2010-08-26
BRPI0812775B8 (pt) 2021-05-25

Similar Documents

Publication Publication Date Title
IL260117A (en) Use of placental cells to treat diseases, syndromes or conditions of the lungs
IL200368A0 (en) Treatment of diseases characterized by inflammation
HK1163500A1 (en) Pharmaceutical composition for the treatment of heart diseases
HK1154382A1 (en) Triazole derivatives useful for the treatment of diseases
PT2049127E (pt) Derivados n-metanocarba para tratamento de doenças cardíacas
HK1144390A1 (en) Compositions for the treatment of neoplastic diseases
ZA201006752B (en) Spiro-indole derivatives for the treatment of parasitic disease
PT1988059E (pt) Processo contínuo para a preparação de nanotubos de titanato de sódio
EP2160100B8 (en) Treatment of graft-versus-host disease
ZA201005116B (en) 6.7-dialkoxy ouinazoline derivatives useful for treatment of cancer related disorders
IL216967B (en) The history of 17-hydroxy-17-pentafluoroethyl-astra-9,4 (10)-diene-11-aryl and their use for the treatment of diseases
HK1141708A1 (en) Agent for treatment of pulmonary disease
PL2056858T3 (pl) Leczenie stanów chorobowych płuc
ZA200905364B (en) Treatment of diseases characterized by inflammation
IL210290A0 (en) Use of pyrimidylaminobenzamide derivatives for the treatment of fibrosis
EP2210621A4 (en) COMPOSITION FOR THE TREATMENT OF JOINT DISEASES
HK1158954A1 (en) 1-amino-alkylcyclohexane derivatives for the treatment of inflammatory skin diseases
EP2157089A4 (en) THERAPEUTIC USES OF IMIDAZOL-5-CARBOXYLIC ACID DERIVATIVES
PT2160190E (pt) Derivados de 5beta, 14 beta-androstano úteis para o tratamento de doenças causadas por fibroses de órgão
PT2278962E (pt) Métodos para o tratamento de desordens dermatológicas
GB0715257D0 (en) Phenylthiazolylpiperazine derivatives for the treatment of nuero degenerative diseases
GB0711463D0 (en) Trimethylsilylbeneylsulphamates as treatments for diseases of bone loss
AU2007905974A0 (en) Treatment of metabolic disease 1
AU2007905975A0 (en) Treatment of metabolic disease 2
GB0700577D0 (en) Composition for heart disease