HK1139855A1 - Specific 3-heteroaryl-3-hydroxy-2-amino-propionic acid amide derivative for use in the treatment of certain cognitive disorders - Google Patents

Specific 3-heteroaryl-3-hydroxy-2-amino-propionic acid amide derivative for use in the treatment of certain cognitive disorders

Info

Publication number
HK1139855A1
HK1139855A1 HK10105998.9A HK10105998A HK1139855A1 HK 1139855 A1 HK1139855 A1 HK 1139855A1 HK 10105998 A HK10105998 A HK 10105998A HK 1139855 A1 HK1139855 A1 HK 1139855A1
Authority
HK
Hong Kong
Prior art keywords
heteroaryl
hydroxy
amino
treatment
specific
Prior art date
Application number
HK10105998.9A
Other languages
English (en)
Inventor
John E Donello
Fabien J Schweighoffer
Lauren M Luhrs
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of HK1139855A1 publication Critical patent/HK1139855A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK10105998.9A 2007-03-06 2010-06-15 Specific 3-heteroaryl-3-hydroxy-2-amino-propionic acid amide derivative for use in the treatment of certain cognitive disorders HK1139855A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89319607P 2007-03-06 2007-03-06
PCT/US2008/055812 WO2008109610A1 (en) 2007-03-06 2008-03-04 Methods for treating cognitive disorders using 3-aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroaryl-3-hydroxy-2-amino-propionic acid amides and related compounds

Publications (1)

Publication Number Publication Date
HK1139855A1 true HK1139855A1 (en) 2010-09-30

Family

ID=39535350

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10105998.9A HK1139855A1 (en) 2007-03-06 2010-06-15 Specific 3-heteroaryl-3-hydroxy-2-amino-propionic acid amide derivative for use in the treatment of certain cognitive disorders

Country Status (12)

Country Link
US (1) US8623891B2 (de)
EP (2) EP2481407B1 (de)
JP (1) JP2010520299A (de)
AU (3) AU2008222890C1 (de)
BR (1) BRPI0808353B8 (de)
CA (1) CA2680324A1 (de)
DK (1) DK2481407T3 (de)
ES (2) ES2711075T3 (de)
HK (1) HK1139855A1 (de)
PT (1) PT2481407T (de)
TR (1) TR201818771T4 (de)
WO (1) WO2008109610A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1841756B1 (de) * 2005-01-26 2011-09-07 Allergan, Inc. 3-heterocyclyl-3-hydroxy-2-amino-propionsäure-amide und damit zusammenhängende verbindungen mit analgesischer und/oder immunostimulatorischer aktivität
NZ582874A (en) * 2007-07-17 2012-06-29 Allergan Inc Methods for treating anxiety
CA2768356A1 (en) * 2009-07-17 2011-01-20 Allergan, Inc. Compositions comprising a cholinesterase inhibitor for treating cognitive disorders
CA2774355A1 (en) 2009-09-16 2011-03-24 Allergan, Inc. Compositions and methods for treating spasticity
WO2011034915A1 (en) * 2009-09-16 2011-03-24 Allergan, Inc. Compositions and methods for treating disorders of gastrointestinal motility
US8242141B2 (en) * 2009-09-16 2012-08-14 Allergan, Inc. Compositions and methods for treating seizure disorders
PT3033327T (pt) * 2013-08-15 2018-04-04 Allergan Inc L)-(+) tartarato de (-)-(2r,3s)-2-amino-3hidroxi-3-piridin-4-il-1-pirrolidin-1-il-propan-1-ona, seus métodos de produção e utilização

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62114946A (ja) 1985-11-13 1987-05-26 Banyu Pharmaceut Co Ltd フエニルセリンアミド誘導体およびそれを有効成分とする中枢神経系用剤
WO1997010817A1 (en) 1995-09-20 1997-03-27 The Regents Of The University Of Michigan Amino ceramide-like compounds and therapeutic methods of use
NO965193L (no) * 1995-12-08 1997-06-09 Seikagaku Kogyo Kk Seikagaku C Aminalkoholderivat og fremgangsmåte for fremstilling derav
GB9909064D0 (en) * 1999-04-20 1999-06-16 Oxford Glycosciences Uk Ltd Therapies
SE9904197D0 (sv) 1999-11-22 1999-11-22 Amersham Pharm Biotech Ab A method for anion exchange adsorption on matrices carrying mixed mode ligands
JP5038582B2 (ja) * 2001-07-16 2012-10-03 ジェンザイム・コーポレーション Udp−グルコース:n−アシルスフィンゴシングルコシルトランスフェラーゼインヒビターの合成
WO2003045928A1 (en) * 2001-11-26 2003-06-05 Genzyme Corporation Diastereoselective synthesis of udp-glucose : n-acylsphingosine glucosyltransferase inhibitors
US20050101674A1 (en) * 2003-11-12 2005-05-12 Maurer Barry J. PPMP as a ceramide catabolism inhibitor for cancer treatment
US20060081273A1 (en) * 2004-10-20 2006-04-20 Mcdermott Wayne T Dense fluid compositions and processes using same for article treatment and residue removal
EP1841756B1 (de) 2005-01-26 2011-09-07 Allergan, Inc. 3-heterocyclyl-3-hydroxy-2-amino-propionsäure-amide und damit zusammenhängende verbindungen mit analgesischer und/oder immunostimulatorischer aktivität
WO2008011485A2 (en) 2006-07-19 2008-01-24 Allergan, Inc. Methods for treating chronic pain
WO2008011483A2 (en) 2006-07-19 2008-01-24 Allergan, Inc. Methods for treating chronic pain using 1- (hetero) aryl-1-hydroxy 2,3-diamino-propyl amines and related compounds

Also Published As

Publication number Publication date
ES2383384T3 (es) 2012-06-20
AU2018204290B2 (en) 2020-05-21
US20100093793A1 (en) 2010-04-15
CA2680324A1 (en) 2008-09-12
WO2008109610A1 (en) 2008-09-12
EP2131837B1 (de) 2012-05-16
AU2008222890B2 (en) 2016-03-31
AU2008222890C1 (en) 2016-09-08
EP2481407B1 (de) 2018-09-26
JP2010520299A (ja) 2010-06-10
TR201818771T4 (tr) 2019-01-21
EP2131837A1 (de) 2009-12-16
AU2016204334A1 (en) 2016-07-14
BRPI0808353B8 (pt) 2021-05-25
DK2481407T3 (en) 2019-01-07
BRPI0808353B1 (pt) 2020-03-31
ES2711075T3 (es) 2019-04-30
BRPI0808353A2 (pt) 2014-07-29
AU2018204290A1 (en) 2018-07-05
AU2016204334B2 (en) 2018-03-15
AU2008222890A1 (en) 2008-09-12
PT2481407T (pt) 2018-12-28
US8623891B2 (en) 2014-01-07
EP2481407A1 (de) 2012-08-01

Similar Documents

Publication Publication Date Title
IL195906A0 (en) Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
ZA201100482B (en) Pyrazolopyrimidines and their use for the treatment of cns disorders
GB201001047D0 (en) Methods and compositions for the treatment of neurological disorders
EP2268140A4 (de) Neue verbindungen, die vorteilhaft für die behandlung von erkrankungen und störungen des zentralnervensystems sind
EP2166837A4 (de) Wirkstoffkombination zur behandlung von hauterkrankungen
HK1158172A1 (en) Compounds for treating ophthalmic diseases and disorders
GB0703909D0 (en) Treatment of anxiety disorders
HK1152939A1 (en) Carboxamide compounds for the treatment of metabolic disorders
EP2278972A4 (de) Behandlung für neurologische und psychische erkrankungen
SI2137141T1 (sl) Arilamidi bifenil-4-il-sulfonske kisline in njihova uporaba kot terapevtska sredstva
HK1139855A1 (en) Specific 3-heteroaryl-3-hydroxy-2-amino-propionic acid amide derivative for use in the treatment of certain cognitive disorders
IL205578A0 (en) Aldh-2 inhibitors in the treatment of psychiatric disorders
GB0915259D0 (en) Sulphur-linked compounds for treating ophthalmic diseases and disorders
ZA200806455B (en) Use of 2-imidazoles for the treatment of CNS disorders
AU2008233088A8 (en) Calcimimetic compounds for use in the treatment of bowel disorders
HK1134032A1 (en) New combination for use in the treatment of inflammatory disorders
IL192877A0 (en) Use of 2-imidazoles for the treatment of cns disorders
IL209417A0 (en) 1-amino-alkylcyclohexane derivatives for the treatment of sleep disorders
EP2099444A4 (de) Verwendung von d-serin-derivaten zur behandlung von angststörungen
PL1982178T3 (pl) Sposoby leczenia zaburzeń afektywnych
IL193943A0 (en) The use of beta- aminoalcohols for the treatment of inflammatory disorders and pain
PT2278962E (pt) Métodos para o tratamento de desordens dermatológicas
IL210558A0 (en) Treatment of anxiety disorders
EP2212246B1 (de) Behandlung von neurologischen störungen
IL193944A0 (en) The use beta-aminoalcohols for the treatment of inflammatory disorders and pain

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160304