HK1138620A1 - 作為重組蛋白和酶技術的工具的 - Google Patents

作為重組蛋白和酶技術的工具的

Info

Publication number
HK1138620A1
HK1138620A1 HK10104595.9A HK10104595A HK1138620A1 HK 1138620 A1 HK1138620 A1 HK 1138620A1 HK 10104595 A HK10104595 A HK 10104595A HK 1138620 A1 HK1138620 A1 HK 1138620A1
Authority
HK
Hong Kong
Prior art keywords
slpa
tool
recombinant protein
enzyme technology
enzyme
Prior art date
Application number
HK10104595.9A
Other languages
English (en)
Inventor
Faatz Elke
Schaarschmidt Peter
Schmitt Urban
Scholz Christian
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1138620A1 publication Critical patent/HK1138620A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
HK10104595.9A 2008-05-26 2010-05-11 作為重組蛋白和酶技術的工具的 HK1138620A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08009537A EP2127678A1 (en) 2008-05-26 2008-05-26 SlpA as a tool for recombinant protein and enzyme technology

Publications (1)

Publication Number Publication Date
HK1138620A1 true HK1138620A1 (zh) 2010-08-27

Family

ID=39590486

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10104595.9A HK1138620A1 (zh) 2008-05-26 2010-05-11 作為重組蛋白和酶技術的工具的

Country Status (7)

Country Link
US (2) US8263086B2 (zh)
EP (2) EP2127678A1 (zh)
JP (1) JP5611540B2 (zh)
CN (1) CN101591665B (zh)
CA (1) CA2667177C (zh)
ES (1) ES2590340T3 (zh)
HK (1) HK1138620A1 (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2617731A1 (en) * 2012-01-19 2013-07-24 Roche Diagnostics GmbH Soluble immunoreactive Treponema pallidum TpN47 antigens
EP2706115A1 (en) 2012-09-06 2014-03-12 Roche Diagnostics GmbH Chaperone-chaperone fusion polypeptides for reduction of interference and stabilization of immunoassays
EP2827146A1 (en) * 2013-07-18 2015-01-21 Roche Diagnostics GmbH Vibrio cholerae lipoprotein 15 (Lp15) variants as anti-interference additive in TpN17-based immunoassays for detection of anti-Treponema antibodies
CN105829892B (zh) * 2013-12-19 2018-06-12 英特维特国际股份有限公司 Csfv抗体的改进的诊断测试
EP2913338A1 (en) * 2014-02-28 2015-09-02 Roche Diagniostics GmbH Soluable and immunoreactive variants of HTLV capsid antigen p24
US10562943B2 (en) 2014-10-24 2020-02-18 University Of Florida Research Foundation, Incorporated Lactobacillus acidophilus surface layer protein A (SlpA) as a therapeutic agent for the treatment of inflammatory diseases
BR112017011662A2 (pt) 2014-12-01 2018-02-27 Pfenex Inc parceiros de fusão para a produção de peptídeo
BR112018072042A2 (pt) 2016-05-31 2019-03-12 Hoffmann La Roche métodos de detecção de polipeptídeo e de processamento prévio de amostras, reagente de processamento prévio, kit de detecção de hcv e uso de composição
WO2017207595A1 (en) 2016-05-31 2017-12-07 Roche Diagnostics Gmbh Pretreatment method for rapid detection of hcv core antigen
EP3577460B1 (en) 2017-02-02 2021-01-20 Roche Diagnostics GmbH Immunoassay using at least two pegylated analyte-specific binding agents
WO2019020599A1 (en) 2017-07-27 2019-01-31 Roche Diagnostics Gmbh MULTIPLE EPITOPE FUSION PROTEIN OF HCV ANTIGEN AND USES THEREOF
US20210373004A1 (en) * 2018-11-19 2021-12-02 Bioaster Methods and reagents for multiplex binding experiments
EP4413020A2 (en) * 2021-10-05 2024-08-14 Viro Research, LLC Herpes simplex virus types 1 and 2 lateral flow assay

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7157089B1 (en) * 1996-11-26 2007-01-02 Stressgen Biotechnologies Corporation Immune responses using compositions containing stress proteins
US5989868A (en) 1997-09-12 1999-11-23 The Board Of Regents Of The University Of Oklahoma Fusion protein systems designed to increase soluble cytoplasmic expression of heterologous proteins in esherichia coli
ATE445016T1 (de) * 2001-06-22 2009-10-15 Hoffmann La Roche Verwendung von fkbp-chaperons als expressionswerkzeug
ATE527345T1 (de) 2006-01-03 2011-10-15 Hoffmann La Roche Chimäres fusionsprotein mit überlegenen chaperon- und faltungsaktivitäten

Also Published As

Publication number Publication date
JP5611540B2 (ja) 2014-10-22
ES2590340T3 (es) 2016-11-21
CA2667177C (en) 2017-08-15
US8263086B2 (en) 2012-09-11
EP2127679A1 (en) 2009-12-02
US8790659B2 (en) 2014-07-29
US20120308994A1 (en) 2012-12-06
EP2127679B1 (en) 2016-06-29
JP2009284902A (ja) 2009-12-10
EP2127678A1 (en) 2009-12-02
CA2667177A1 (en) 2009-11-26
CN101591665A (zh) 2009-12-02
CN101591665B (zh) 2016-08-31
US20090291892A1 (en) 2009-11-26

Similar Documents

Publication Publication Date Title
HK1138620A1 (zh) 作為重組蛋白和酶技術的工具的
HUE046149T2 (hu) Fehérje
ZA200810738B (en) Polypeptide
GB0611116D0 (en) Proteins
EP2447364A4 (en) MODIFIED PROTEIN CONJUGATED TO BIOTIN
EP2462237A4 (en) METHODS OF ENHANCING EXPRESSION OF RECOMBINANT PROTEIN
EP2133416A4 (en) RECOMBINANT MICROORGANISM
GB2466379B (en) Protein stabilizer
GB0601976D0 (en) Proteins
GB0816976D0 (en) Protein
ZA201100019B (en) Variant hhip1 protein and methods and uses thereof
GB0620735D0 (en) Proteins
GB0610140D0 (en) Protein stability
HK1157381A1 (zh) 改良的生物素結合蛋白
EP2172550A4 (en) C-TERMINAL-A-AMIDATED RECOMBINANT ENZYME DERIVATIVE
GB0719231D0 (en) Protein
EP2024516A4 (en) Perforin-2 PROTEINS
EP2167665A4 (en) PROCESS FOR IMPROVING RECOMBINANT PROTEIN PRODUCTION
EP1985695A4 (en) RECOMBINANT MICROORGANISM
GB0612443D0 (en) Protein
GB0813253D0 (en) Protein expression system
GB2462726B (en) Protein expression
GB0818627D0 (en) Protein
GB0620304D0 (en) Protein
GB0720563D0 (en) Protein