HK1134288A1 - Process for preparing substantially pure fluorescein - Google Patents

Process for preparing substantially pure fluorescein

Info

Publication number
HK1134288A1
HK1134288A1 HK09111726.9A HK09111726A HK1134288A1 HK 1134288 A1 HK1134288 A1 HK 1134288A1 HK 09111726 A HK09111726 A HK 09111726A HK 1134288 A1 HK1134288 A1 HK 1134288A1
Authority
HK
Hong Kong
Prior art keywords
substantially pure
preparing substantially
pure fluorescein
fluorescein
preparing
Prior art date
Application number
HK09111726.9A
Other languages
English (en)
Inventor
Gregory Bydlinski
Gregg Robert Harris
Britt S Scott
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39327263&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1134288(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of HK1134288A1 publication Critical patent/HK1134288A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
HK09111726.9A 2006-12-11 2009-12-14 Process for preparing substantially pure fluorescein HK1134288A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86948806P 2006-12-11 2006-12-11
PCT/US2007/086390 WO2008073764A2 (en) 2006-12-11 2007-12-04 Substantially pure fluorescein

Publications (1)

Publication Number Publication Date
HK1134288A1 true HK1134288A1 (en) 2010-04-23

Family

ID=39327263

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09111726.9A HK1134288A1 (en) 2006-12-11 2009-12-14 Process for preparing substantially pure fluorescein

Country Status (17)

Country Link
US (1) US7982056B2 (xx)
EP (2) EP2114953B1 (xx)
JP (2) JP5384363B2 (xx)
KR (2) KR101571409B1 (xx)
CN (1) CN101605796B (xx)
AR (1) AR064288A1 (xx)
AU (1) AU2007333307B2 (xx)
BR (1) BRPI0720088A2 (xx)
CA (1) CA2671860C (xx)
CL (1) CL2007003593A1 (xx)
ES (1) ES2387925T3 (xx)
HK (1) HK1134288A1 (xx)
MX (1) MX2009005679A (xx)
RU (1) RU2477284C2 (xx)
TW (1) TWI518089B (xx)
WO (1) WO2008073764A2 (xx)
ZA (1) ZA200903447B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009005679A (es) * 2006-12-11 2009-06-08 Alcon Res Ltd Fluoresceina sustancialmente pura.
JP6660399B2 (ja) 2015-03-10 2020-03-11 ローズ テクノロジーズ ブプレノルフィンの酢酸塩及びブプレノルフィンの調製方法
JP2017095453A (ja) * 2015-11-12 2017-06-01 参天製薬株式会社 高純度フルオレセインナトリウム
US10293047B1 (en) 2017-11-15 2019-05-21 Paragon BioTeck, Inc. Fluorescein and benoxinate compositions
CN113461651A (zh) * 2021-08-20 2021-10-01 山东绅联药业有限公司 一种高纯度荧光素的纯化方法
WO2023037158A1 (en) * 2021-09-09 2023-03-16 Macsen Drugs Process for preparation of crystalline fluorescein sodium from diacetylfluorescein or fluorescein
WO2023172587A1 (en) * 2022-03-07 2023-09-14 Opus Life Sciences Llc Fluorescein formulations and kits

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1965842A (en) 1931-11-21 1934-07-10 Nat Aniline & Chem Co Inc Production of hydroxybenzenephthaleins
DD136498A1 (de) * 1978-05-11 1979-07-11 Friedmut Friedrich Verfahren zur herstellung von hochgereinigtem fluorescein fuer injektionszwecke
US5188934A (en) * 1989-11-14 1993-02-23 Applied Biosystems, Inc. 4,7-dichlorofluorescein dyes as molecular probes
US5637733A (en) * 1995-09-27 1997-06-10 Warner-Jenkinson Company, Inc. Syntheses of fluorescein compounds with excess resorcinol as a solvent
US6162931A (en) * 1996-04-12 2000-12-19 Molecular Probes, Inc. Fluorinated xanthene derivatives
DE19923168A1 (de) * 1999-05-20 2000-11-23 Roche Diagnostics Gmbh Neue Fluoreszenzfarbstoffe und ihre Verwendung als Fluoreszenzmarker
FR2846331B1 (fr) * 2002-10-29 2006-11-17 Synth Innove Lab Phtaleines de purete elevee et leur procede de preparation
RU2287007C1 (ru) * 2005-07-28 2006-11-10 Борис Маркович Болотин Бесцветные, растворимые в воде органические люминофоры
MX2009005679A (es) * 2006-12-11 2009-06-08 Alcon Res Ltd Fluoresceina sustancialmente pura.

Also Published As

Publication number Publication date
CN101605796B (zh) 2012-10-03
TW200838864A (en) 2008-10-01
CA2671860A1 (en) 2008-06-19
JP2013241472A (ja) 2013-12-05
EP2114953A2 (en) 2009-11-11
RU2477284C2 (ru) 2013-03-10
US7982056B2 (en) 2011-07-19
RU2009126572A (ru) 2011-01-20
AR064288A1 (es) 2009-03-25
CN101605796A (zh) 2009-12-16
EP2481741A1 (en) 2012-08-01
MX2009005679A (es) 2009-06-08
KR20150013356A (ko) 2015-02-04
WO2008073764A3 (en) 2009-07-30
CA2671860C (en) 2016-07-12
CL2007003593A1 (es) 2008-08-22
AU2007333307B2 (en) 2013-05-23
AU2007333307A1 (en) 2008-06-19
BRPI0720088A2 (pt) 2013-12-24
TWI518089B (zh) 2016-01-21
EP2114953B1 (en) 2012-06-06
WO2008073764A2 (en) 2008-06-19
KR20090086620A (ko) 2009-08-13
KR101571409B1 (ko) 2015-11-24
ES2387925T3 (es) 2012-10-04
JP2010512409A (ja) 2010-04-22
ZA200903447B (en) 2010-08-25
JP5384363B2 (ja) 2014-01-08
US20080176930A1 (en) 2008-07-24

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20181204