HK1133391A1 - Generating an immune response by inducing cd40 and pattern recognition receptors cd40 - Google Patents

Generating an immune response by inducing cd40 and pattern recognition receptors cd40

Info

Publication number
HK1133391A1
HK1133391A1 HK10100140.7A HK10100140A HK1133391A1 HK 1133391 A1 HK1133391 A1 HK 1133391A1 HK 10100140 A HK10100140 A HK 10100140A HK 1133391 A1 HK1133391 A1 HK 1133391A1
Authority
HK
Hong Kong
Prior art keywords
inducing
generating
immune response
pattern recognition
recognition receptors
Prior art date
Application number
HK10100140.7A
Other languages
English (en)
Chinese (zh)
Inventor
David Spencer
Natalia LAPTEVA
Original Assignee
Baylor College Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Medicine filed Critical Baylor College Medicine
Publication of HK1133391A1 publication Critical patent/HK1133391A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK10100140.7A 2006-10-19 2010-01-08 Generating an immune response by inducing cd40 and pattern recognition receptors cd40 HK1133391A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86221106P 2006-10-19 2006-10-19
US89508807P 2007-03-15 2007-03-15
PCT/US2007/081963 WO2008049113A2 (en) 2006-10-19 2007-10-19 Generating an immune response by inducing cd40 and pattern recognition receptors

Publications (1)

Publication Number Publication Date
HK1133391A1 true HK1133391A1 (en) 2010-03-26

Family

ID=39314865

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10100140.7A HK1133391A1 (en) 2006-10-19 2010-01-08 Generating an immune response by inducing cd40 and pattern recognition receptors cd40

Country Status (6)

Country Link
US (5) US8691210B2 (de)
EP (3) EP2076272B1 (de)
AU (3) AU2007310946B2 (de)
CA (2) CA2666667C (de)
HK (1) HK1133391A1 (de)
WO (1) WO2008049113A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8981061B2 (en) 2001-03-20 2015-03-17 Novo Nordisk A/S Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof
ES2543084T3 (es) 2003-02-18 2015-08-14 Baylor College Of Medicine Activación inducida en células dendríticas
CA2666667C (en) 2006-10-19 2023-06-20 Baylor College Of Medicine Generating an immune response by inducing cd40 and pattern recognition receptors
EP2331680B1 (de) 2008-09-22 2017-05-03 Baylor College Of Medicine Verfahren und zusammensetzungen zur erzeugung einer immunreaktion mittels cd40-induktion sowie strukturerkennungsrezeptoradaptern
WO2011130566A2 (en) * 2010-04-16 2011-10-20 Bellicum Pharmaceuticals, Inc. Method for treating solid tumors
US9089520B2 (en) 2010-05-21 2015-07-28 Baylor College Of Medicine Methods for inducing selective apoptosis
US9550830B2 (en) 2012-02-15 2017-01-24 Novo Nordisk A/S Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
EP2814844B1 (de) 2012-02-15 2017-08-02 Novo Nordisk A/S Antikörper, die den auslösenden rezeptor binden und blockieren, der auf myeloid-zellen-1 (trem-1) exprimiert ist
CN104203977A (zh) 2012-02-15 2014-12-10 诺和诺德A/S（股份有限公司） 结合肽聚糖识别蛋白1的抗体
US10093701B2 (en) 2012-09-07 2018-10-09 University Of Miami Fusion proteins for promoting an immune response, nucleic acids encoding same, and methods of making and use thereof
US9434935B2 (en) 2013-03-10 2016-09-06 Bellicum Pharmaceuticals, Inc. Modified caspase polypeptides and uses thereof
JP6541639B2 (ja) * 2013-03-14 2019-07-10 ベリカム ファーマシューティカルズ， インコーポレイテッド Ｔ細胞増殖をコントロールするための方法
ES2791598T3 (es) 2013-06-05 2020-11-05 Bellicum Pharmaceuticals Inc Métodos para inducir apoptosis parcial utilizando polipéptidos de caspasa
CA2937750A1 (en) 2014-02-14 2015-08-20 Bellicum Pharmaceuticals, Inc. Methods for activating t cells using an inducible chimeric polypeptide
CN106536559B (zh) 2014-07-17 2021-04-27 诺和诺德股份有限公司 定点诱变trem-1抗体以降低黏度
EP3189148A4 (de) 2014-09-02 2018-05-02 Bellicum Pharmaceuticals, Inc. Co-stimulierung von chimären antigenrezeptoren durch myd88- und cd40-polypeptide
EP3215522B1 (de) 2014-11-03 2021-12-01 Academisch Ziekenhuis Leiden H.O.D.N. Leids Universitair Medisch Centrum Gegen bob1 gerichtete t-zell-rezeptoren und verwendungen davon
WO2018085533A2 (en) * 2016-11-02 2018-05-11 Apexigen, Inc. Anti-cd40 antibodies in combination and methods of use
EP3621988A1 (de) 2017-05-09 2020-03-18 Bellicum Pharmaceuticals, Inc. Verfahren zur verstärkung oder änderung der signaltransduktion
MX2020004185A (es) * 2017-09-27 2021-01-08 Univ Southern California Nuevas plataformas para coestimulacion, nuevos diseños car y otras mejoras para terapia celular adoptiva.
US20200347148A1 (en) 2017-12-08 2020-11-05 Bellicum Pharmaceuticals, Inc. Methods for enhancing and maintaining car-t cell efficacy
US20200308144A1 (en) 2017-12-20 2020-10-01 Bellicum Pharmaceuticals, Inc. Multimeric piperidine derivatives
KR20200139219A (ko) 2018-04-02 2020-12-11 브리스톨-마이어스 스큅 컴퍼니 항-trem-1 항체 및 이의 용도
WO2021168274A1 (en) 2020-02-21 2021-08-26 Silverback Therapeutics, Inc. Nectin-4 antibody conjugates and uses thereof
TW202216211A (zh) 2020-07-01 2022-05-01 美商希沃爾拜克治療公司 抗asgr1抗體共軛物及其用途

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4514506A (en) 1982-02-23 1985-04-30 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services Method for the identification and purification of human lung tumor-associated antigens (hLTAA) and clinical detection and determination of these antigens
EP0273085A1 (de) 1986-12-29 1988-07-06 IntraCel Corporation Verfahren zur Einführung fremder Nukleinsäuren in eukaryotische Zellen
FR2610631B1 (fr) 1987-02-09 1989-11-24 Pasteur Institut Molecules comportant au moins une sequence peptidique porteuse d'un ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum dans les hepatocytes, et leurs utilisations, notamment pour le diagnostic du paludisme ou dans des compositions de vaccins contre le paludisme
US5869608A (en) 1989-03-17 1999-02-09 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and amino acid sequences of the four variable domains of the major outer membrane proteins of Chlamydia trachomatis
US5550318A (en) 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5484956A (en) 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
US5384253A (en) 1990-12-28 1995-01-24 Dekalb Genetics Corporation Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
GB9105383D0 (en) 1991-03-14 1991-05-01 Immunology Ltd An immunotherapeutic for cervical cancer
DE69233441T2 (de) 1991-04-26 2005-10-13 Osaka Bioscience Institute, Suita Menschliches Zelloberflächen-Antigen codierende DNA
US5780036A (en) 1991-08-26 1998-07-14 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepattis B virus
US5610042A (en) * 1991-10-07 1997-03-11 Ciba-Geigy Corporation Methods for stable transformation of wheat
DE4228457A1 (de) * 1992-08-27 1994-04-28 Beiersdorf Ag Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen
GB9222888D0 (en) 1992-10-30 1992-12-16 British Tech Group Tomography
US5348253A (en) * 1993-02-01 1994-09-20 Gratzer Louis B Blended winglet
US5834266A (en) * 1993-02-12 1998-11-10 President & Fellows Of Harvard College Regulated apoptosis
EP1978095A1 (de) * 1993-02-12 2008-10-08 The Board Of Trustees Of The Leland Stanford Junior University Regulierte Transkription gezielter Gene und anderer biologischer Ereignisse
US5830462A (en) * 1993-02-12 1998-11-03 President & Fellows Of Harvard College Regulated transcription of targeted genes and other biological events
US5869337A (en) * 1993-02-12 1999-02-09 President And Fellows Of Harvard College Regulated transcription of targeted genes and other biological events
US5426027A (en) 1993-05-20 1995-06-20 The Government Of The United States Of America As Represented By The Secretary Nucleic acid probes and methods for detecting Candida DNA cells in blood
US5648226A (en) 1993-07-22 1997-07-15 Ludwig Institute For Cancer Research Isolated peptides derived from tumor rejection antigens, and their use
NZ271774A (en) 1993-08-06 1998-02-26 Cytel Corp Immunogenic peptides from the c-terminus of the mage-1 (melanoma) antigen
US5550214A (en) 1994-02-10 1996-08-27 Brigham And Women's Hospital Isolated antigenic oncogene peptide fragments and uses
US5709995A (en) 1994-03-17 1998-01-20 The Scripps Research Institute Hepatitis C virus-derived peptides capable of inducing cytotoxic T lymphocyte responses
FR2722208B1 (fr) * 1994-07-05 1996-10-04 Inst Nat Sante Rech Med Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique
AU3968595A (en) 1994-10-25 1996-05-15 Board Of Trustees Of The Leland Stanford Junior University Conditional transformation of genetically engineered cells
US5741899A (en) * 1995-02-02 1998-04-21 Cell Genesys, Inc. Chimeric receptors comprising janus kinase for regulating cellular pro liferation
US5600042A (en) 1995-04-27 1997-02-04 Chen; Wu-Chi Process for the production of vinyl chloride
US5840839A (en) 1996-02-09 1998-11-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein
US5853719A (en) * 1996-04-30 1998-12-29 Duke University Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
WO1998001538A1 (en) 1996-07-10 1998-01-15 Immunex Corporation Method of activating dendritic cells
US5955596A (en) * 1996-07-26 1999-09-21 American Cyanamid Company NucA protein of Haemophilus influenzae and the gene encoding that protein
US6046158A (en) * 1996-12-20 2000-04-04 Board Of Regents The University Of Texas Systems Unique dendritic cell-associated C-type lectins, dectin-1 and dectin-2; compositions and uses thereof
US5965242A (en) 1997-02-19 1999-10-12 Eastman Kodak Company Glow-in-the-dark medium and method of making
US6969609B1 (en) * 1998-12-09 2005-11-29 The United States Of America As Represented By The Department Of Health And Human Serivces Recombinant vector expressing multiple costimulatory molecules and uses thereof
US6558951B1 (en) 1999-02-11 2003-05-06 3M Innovative Properties Company Maturation of dendritic cells with immune response modifying compounds
GB9930616D0 (en) * 1999-12-24 2000-02-16 Mathilda & Terence Kennedy Ins Activation and inhibition of the immune system
US20030108527A1 (en) * 1999-12-28 2003-06-12 Tsukasa Seya Maturation-promoting agent for immature dendrtic cells
US7435585B2 (en) * 2000-01-03 2008-10-14 University Of Pennsylvania Auto-stimulating cells and methods for making and using the same
SE0001642D0 (sv) 2000-05-04 2000-05-04 Sahltech Ab Reagent for detection of biomolecules, and use thereof
US20030232055A1 (en) * 2000-07-31 2003-12-18 Ruslan Medzhitov Innate immune system-directed vaccines
AU2001281252A1 (en) * 2000-08-10 2002-02-18 Board Of Regents, The University Of Texas System The tumor suppressor car-1
WO2002036769A2 (en) 2000-10-31 2002-05-10 F. Hoffmann-La Roche Ag Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
AU2002354560A1 (en) * 2001-07-09 2003-01-29 Oklahoma Medical Research Foundation Targeted fusion proteins and methods for the characterization of cellular membrane domains
JP4360906B2 (ja) * 2001-09-14 2009-11-11 サイトス バイオテクノロジー アーゲー ウィルス様粒子によって誘導される免疫応答を高めるための、抗原提示細胞のインビボでの活性化
US20050215472A1 (en) * 2001-10-23 2005-09-29 Psma Development Company, Llc PSMA formulations and uses thereof
US20030082163A1 (en) * 2001-10-26 2003-05-01 Suyu Shu Fused cells, methods of forming same, and therapies utilizing same
AU2003223244A1 (en) * 2002-03-11 2003-09-29 The Johns Hopkins University Molecular switches and methods for making and using the same
ES2543084T3 (es) 2003-02-18 2015-08-14 Baylor College Of Medicine Activación inducida en células dendríticas
WO2007050095A2 (en) * 2004-11-19 2007-05-03 The Trustees Of The University Of Pennsylvania Improved vaccines and methods for using the same
KR100705981B1 (ko) * 2005-10-12 2007-04-10 주식회사 리제론 인간 성장호르몬을 포함하는 탈모방지 또는 발모촉진용조성물
US20100196336A1 (en) * 2006-05-23 2010-08-05 Dongsu Park Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
CA2666667C (en) 2006-10-19 2023-06-20 Baylor College Of Medicine Generating an immune response by inducing cd40 and pattern recognition receptors
EP2224954B1 (de) * 2007-11-07 2014-01-08 Celldex Therapeutics, Inc. Menschliche dendritische und epithelzellen 205 (dec-205) bindende antikörper
CA2717538A1 (en) * 2008-03-03 2009-09-11 Dyax Corp. Metalloproteinase 12 binding proteins
EP2331680B1 (de) * 2008-09-22 2017-05-03 Baylor College Of Medicine Verfahren und zusammensetzungen zur erzeugung einer immunreaktion mittels cd40-induktion sowie strukturerkennungsrezeptoradaptern
WO2011130566A2 (en) 2010-04-16 2011-10-20 Bellicum Pharmaceuticals, Inc. Method for treating solid tumors

Also Published As

Publication number Publication date
EP2465511A3 (de) 2012-10-10
EP2465511B1 (de) 2019-05-22
AU2014202528B2 (en) 2016-09-15
AU2007310946B2 (en) 2014-06-05
CA2666667A1 (en) 2008-04-24
AU2007310946A1 (en) 2008-04-24
EP2076272A4 (de) 2009-09-16
US20240034771A1 (en) 2024-02-01
AU2016273887A1 (en) 2017-01-05
WO2008049113A3 (en) 2009-01-08
US20180201663A1 (en) 2018-07-19
US8691210B2 (en) 2014-04-08
US20110033383A1 (en) 2011-02-10
WO2008049113A2 (en) 2008-04-24
EP2076272B1 (de) 2015-07-29
AU2014202528A1 (en) 2014-05-29
US20210002347A1 (en) 2021-01-07
CA3058450A1 (en) 2008-04-24
US20140287490A1 (en) 2014-09-25
EP2465510B1 (de) 2018-11-28
EP2465511A2 (de) 2012-06-20
EP2076272A2 (de) 2009-07-08
CA2666667C (en) 2023-06-20
EP2465510A3 (de) 2012-10-03
EP2465510A2 (de) 2012-06-20

Similar Documents

Publication Publication Date Title
HK1133391A1 (en) Generating an immune response by inducing cd40 and pattern recognition receptors cd40
EP2331680A4 (de) Verfahren und zusammensetzungen zur erzeugung einer immunreaktion mittels cd40-induktion sowie strukturerkennungsrezeptoradaptern
IL232518A0 (en) A yeast-based vaccine to stimulate an immune response
GB0409799D0 (en) Method of generating improved immune response
IL195475A0 (en) Neuropsychological spatiotemporal pattern recognition
GB0618196D0 (en) An improved mist generating apparatus and method
GB0715073D0 (en) Training apparatus
EP1715377A4 (de) Einrichtung zur erzeugung elektromagnetischer wellen
ZA200703394B (en) Combination approaches for generating immune responses
ZA200810729B (en) Spray device
GB0625617D0 (en) Limb training device
EP2084263A4 (de) Verfahren zur herbeiführung einer kardiomyogenese
EP2165116A4 (de) Unmittelbar ansprechendes dampferzeugungssystem und verfahren
TWI372257B (en) Waveform generating device, waveform generating method and program
EP2066341A4 (de) Verfahren zur auslösung oder einleitung einer immunantwort
EP2114416A4 (de) Verfahren zur auslösung einer immunantwort
EP2257182A4 (de) Verstellbarer dampfinjektor
GB0602136D0 (en) Spray device
GB2444319B (en) Training apparatus
GB0623408D0 (en) Energy generating system
FR2910795B1 (fr) Appareil de cuisson sous pression
GB2436595B (en) Wavecycle generator
TWM299038U (en) Vibrating apparatus
GB2420321B (en) Energy generating apparatus
IL198085A (en) Physical Workout Device

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20191017